1. Pharmaceutical Dosage Modules Power Point Presentation

2. Instructions
Be sure to work through the problems before attempting to watch the lecture tapes.
After working through the problems as much as you can, watch the tapes for the necessary steps needed to solve the problems correctly.
Remember practice makes perfect when working dosage problems

3. Good Luck with the Modules!!!

4. Dr. R. R. Espinosa, R.Ph., Pharm. D.
Pharmacology Dosage Modules I-V

5. Dosage Modules Module #1 Dimensional Analysis
Module #2 Basic Dosage Calculations
Module #3 Reconstitution
Module #4 Basic IV Dosage Calculations
Module #5 Advanced Intravenous Calculations

6. Pharmaceutical Dosage Module 1 : Dimensional Analysis

7. Dimensional Analysis
Given Quantity: the beginning point of the problem
Conversion Factors- Equivalents necessary to convert between systems of measurement and to allow unwanted units to be cancelled from the problem

8. Dimensional Analysis
Unit Path: the series of conversions necessary to achieve the Wanted Quantity
Wanted Quantity: the answer to the problem

9. Converting Within and Between Systems of Measurement

10. System of Measurement Household: tsp, gtt, T, c Apothecary: gr, dr, oz
Metric: ml, mg, g, l

11. Conversion Problems 350 mg =_______g 0.016 g =_______mg
0.16 kg =_______lb
8 mg = _______gr
0.07 mg =______mcg
500 ml = _______L
45 gr = _______mg

12. Conversion Problems issgr =_________g xx drams =_____ml
75 ml =________oz
vss oz =_______ml
9 g =__________gr
102 lb =_______kg
3 tsp =________ml

13. Conversions problems 3 ml =_________Minims 4 drams =______oz
iv gr =_________mg
25 L = ______ml
1/300 gr =______mg
200ml =________tsp
6 tsp =_________T

14. Answers to problems Not covered on lecture tape
4drams=0.67oz
4 gr=240mg
25L=25000ml
200ml=40tsp
6tsp=2T

15. Pharmaceutical Dosage Module 2: Basic Dosage Calculations

16. Dosage Calculations
The doctor orders a patient to receive Daypro 1200mg q am and pm. The stock supply is 600mg/tab. How many tablets will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

18. Dosage Calculations
The doctor orders a patient to receive Daypro 1200mg q am and pm. The stock supply is 600mg/tab. How many tablets will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

19. Dosage calculations
A patient is to receive Doxycycline 5 gr po qid for infection. The stock supply is 100mg/caps. How many capsules will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

21. Dosage calculations
A patient is to receive Doxycycline 5 gr po qid for infection. The stock supply is 100mg/caps. How many capsules will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

22. Dosage Calculations
Patient is to receive 0.5 g of Zocor q hs for cholesterol. The stock supply is 20mg/tab. How many tablets will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

24. Dosage Calculations
MD orders the client to have 1/8 gr of Estratab qod. The stock supply is 1.25 mg tablet. How many tablets will the patient receive for the correct dose?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

26. Dosage Calculations
Patient is to receive 70 mg IM stat of Solu-Medrol. The stock supply is 125mg/2ml. How many ml’s is the patient going to receive for the correct dose?
Given Quantity -Dose on Hand
Wanted Quantity -Answer

27. Dosage Calculations
Dr orders Trimox 0.5 g q 6 h for infection. The stock supply is 250mg/5ml. The total volume is 100ml. How many ml’s will the patient receive for the correct dose? How may teaspoonfuls will the patient receive for each dose?
Given Quantity -Dose on Hand
Wanted Quantity Answer

29. Dosage Calculations Given Quantity -Dose on Hand
Patient is to receive Atropine 0.2mg Sub Q stat, then 0.15 mg every 6 hours as needed. The stock supply is 400mcg/ml. How many ml’s will the patient receive for the first dose? How many ml’s will the patient receive on each subsequent dose?
Given Quantity -Dose on Hand
Wanted Quantity -Answer

30. Dosage Calculations -Given Quantity -Dose on Hand
Patient is to receive Gentamicin ¼ gr IV q 4 h for infection. The stock supply is 15mg/ml. How many ml’s will the patient receive for the correct dose? How often is this medication given? What is the route of administration?
-Given Quantity -Dose on Hand
-Wanted Quantity -Answer

31. Pharmaceutical Dosage Module 3: Reconstitution

32. Reconstitution
The doctor orders Ancef 750mg IM q 8 h. The stock supply is a 1.0 g vial of powdered Ancef. Directions say to reconstitute with 2.5 ml of water to produce a total volume of 3 ml.
How many ml’s will you give to the patient for the correct dose?
How many mg’s will the patient receive for the correct dose in 24 hours(1 day)?
How many grams will the patient receive in 24 hours?

33. Reconstitution
The doctor orders Ancef 750mg IM q 8 h. The stock supply is a 1.0 g vial of powdered Ancef. Directions say to reconstitute with 2.5 ml of water to produce a total volume of 3 ml.
How many ml’s will you give to the patient for the correct dose?
How many mg’s will the patient receive for the correct dose in 24 hours(1 day)?
How many grams will the patient receive in 24 hours?

34. Reconstitution
Patient is to receive 3 g of Ampicillin to be added to a 1000ml D-5-W IV q 8 h. The stock supply is a 10,000mg Ampicillin vial. Directions say to reconstitute with 9.8 ml of NS to yield 500mg/ml.
How many ml’s of Ampicillin will you add to the IV bag for the correct dose?

35. Reconstitution
Patient is to receive 3 g of Ampicillin to be added to a 1000ml D-5-W IV q 8 h. The stock supply is a 10,000mg Ampicillin vial. Directions say to reconstitute with 9.8 ml of NS to yield 500mg/ml.
How many ml’s of Ampicillin will you add to the IV bag for the correct dose?

36. Reconstitution
Patient is to receive Nafcillin 5 gr IM q 6 hours for infection. The stock supply is a 2 g vial. The directions say to add 6.6 ml of sterile water to yield 250mg/ml. The total volume in the vial is 8ml.
How many ml’s will the patient receive for the correct dose?
How often is the patient receiving the medication?

37. Reconstitution
Suprax 0.4g po q d for 12 days is order for a patient for infection. The stock supply is a 2 g bottled powder. The directions says to reconstitute with 69 ml of water. This will provide 100mg/ml.
How many ml’s will the patient receive for one dose?
What would be the total ml’s for the entire dose?

38. Reconstitution
Client is to receive Cephalexin 2 g IV qid for infection. The stock supply is a 2 gram vial. Directions say to add 5ml of sterile water for injection, this will yield a concentration of 160mg/ml.
How may ml’s will the patient receive for the correct dose?
How often is the patient to receive this dose?

39. Reconstitution
MD orders Timentin 8 gr IV tid. Timentin is available in a 3.1g powder. Directions say to use 13 ml of sterile water for injection. The concentration will be approximately 200mg/ml.
How many ml’s will be administered for the correct dose?

40. Pharmaceutical Dosage Module 4: Basic IV Dosage Calculations

41. Calculating Intravenous Flow Rates
Electronic
vs.
Manual Infusion Devise

42. Electronic IV flow rate pump delivers volume in ml/hr
Nurses responsibility to program the pump
Amount of fluid/over period of time

43. Manual IV flow rate must be determined in gtts/min
Nurses responsibility to count the number of drips that drop in a minute into the drip chamber
The IV tubing provides the drop factor, which is calibrated in drops/ml

44. Basic IV Calculations
A client on an infusion pump is to receive an antibiotic in 50 ml 0.9% NS over 30 minutes. What is the flow rate in ml per hour?
Given Quantity
Wanted Quantity
Answer

45. Medication involving Intravenous pump
A client on an infusion pump is to receive 500ml of R/L in 12 hours. What is the flow rate in ml per hour?
Given Quantity
Wanted Quantity
Answer

46. Medication involving Intravenous pump
The doctor orders 100ml of D-5-W to infuse in 20 minutes q 4 hours. What is the flow rate in ml/hr?
Given Quantity
Wanted Quantity
Answer

47. Medication Problem Involving a Drop Factor
The doctor orders 150 ml of D5W to be infused over 45 minutes q 4 hours. The drop factor is 20 gtts per ml. What is the flow rate in drops per minute?
Given Quantity
Wanted Quantity
Drop factor
Answer

48. Basic IV Calculations
The doctor orders 250 ml of D-5-W IV q 3 hours. The drop factor is 20 gtts/ml. What is the flow rate in gtts/min? What is the flow rate in ml/hr?
Given Quantity
Wanted Quantity
Drop Factor
Answer

49. Pharmaceutical Dosage Module 5: Advanced Intravenous Calculations

50. The MD orders 10,000 units of Penicillin to be added to the IVPB of 100ml of NS to infuse in 45 minutes every 6 hours. Stock supply is a vial containing 2,000,000 units of Penicillin. Directions says to reconstitute with 9.8 ml to yield a 10 ml total volume. The drop factor for the IVPB is 15 gtts/ml.
How many ml’s of penicillin will you add to the IVPB for the correct dose?
What is flow rate in gtts per min for the IVPB?
What is the flow rate in ml per hour?

51. What is the flow rate in gtts per min for the IVPB?
The MD orders 10,000 units of Penicillin to be added to the IVPB of 100ml of NS to infuse in 45 minutes every 6 hours. The stock supply is a vial containing 2,000,000 units of Penicillin. Directions says to reconstitute with 9.8 ml to yield a 10 ml total volume. The drop factor for the IVPB is 15 gtts/ml.
How many ml’s of penicillin will you add to the IVPB for the correct dose?
What is the flow rate in gtts per min for the IVPB?
What is the flow rate in ml per hour?

52. Advanced Intravenous Calculations
Dopamine 2mcg/kg/min is order for a patient. The pharmacy sends an IV bag labeled: Dopamine 400mg/ 250 ml D5W. The client weighs 150 lbs.
-What is the flow rate in ml’s per hour?
Given Quantity -Dose on Hand
Wanted Quantity -Answer

53. Advanced Intravenous Calculations
MD orders Nipride 3mcg/kg/min. The pharmacy sends a bag labeled: Nipride 50mg/ 250 ml of NS. The drop factor is 15 gtts/ml. The patient weighs 110 lbs.
-Calculate the ml/hr to set the IV pump? What is the flow rate in gtts/min?
Given Quantity -Dose on Hand
Wanted Quantity -Answer

54. Advanced Intravenous Calculations
Dobutamine 500mg in 250 ml D5W to infuse at 10mcg/kg/min. The client weighs 250 lbs.
-What is the flow rate in ml/hr? What is the flow rate in drops/minute with a drop factor of 60 gtts/ml?
Given Quantity -Dose on Hand
Wanted Quantity -Answer

55. Conclusion
I hope this has helped you achieve yours goals of understanding different types of dosage calculations that you will encounter in this class and on into your careers.
Good Luck, Allied Health Science Faculty