1. Homework 12 Welcome to the HIV cost calculator A tool to assist in answering the question "Why not test everyone?"

2. Assignment Questions 1)Compare two different testing strategies. For each, list the sensitivity, specificity, false positive, false negative, positive predictive value, and total cost in both a high and low prevalence setting. Is the cost of the more expensive one justifiable? Which strategy would you recommend under what circumstances? 2)In 2002, the US Congress spent $143,800,000.00 on the CDC Global AIDS program. How inexpensive would your screening test have to be (with a sensitivity of 99.9% and specificity of 99.9%) to be able to screen the population of Uganda (25,632,794) which has a prevalence of 5% and not be over budget for the entire CDC Global AIDS program? Go to cost calculator part AGo to cost calculator part BGo to references

3. Go to cost calculator part BGo to referencesGo to assignments questions

4. Go to assignment questions Go to cost calculator part A Go to references

5. Sensitivity and Specificity references online Abbott HIVAG-1 Monoclonal ELISA http://www.phppo.cdc.gov/mpep/pdf/p24/9806p24a.pdf Serum Western Blot http://www.musc.edu/dc/icrebm/sensitivity.html Urine ELISA http://hivinsite.ucsf.edu/InSite?page=kb-03-01-02#S8X Urine Western Blot http://www.fda.gov/cber/label/hiv1cam052898Lb.pdf Oraquick http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5146a5.htm HIV DNA PCR http://www.retroconference.org/2001/posters/243.pdf Home Access http://www.fda.gov/cber/PMAsumm/P950002S.pdf HIV CHEK http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Search&DB=PubMed Discreet http://www.aidshivtest.com/ Health Diagnostics http://www.health-diagnostics.net/store/hi.php?lang=en Go to cost calculator part AGo to cost calculator part BGo to assignment questions