1. These slides were sponsored by Janssen and developed in conjunction with the BRS CKD Strategy Group, following an advisory board that was organised by Janssen. Bedrock Healthcare Communications provided editorial support to members of the advisory board in developing the slides. Janssen reviewed the content for technical accuracy. The content is intended for a UK healthcare professional audience only. JOB CODE PHGB/VOK/0914/0018i Date of preparation: January 2015 SECTION J Sources of further information and reading list

2. Objectives and background for this learning resource Introduction: This learning resource has been developed as part of a medical education initiative supported by Janssen. The content of this slide kit has been developed by an advisory board of renal physicians, GPs and specialist nurses. The panel of experts includes members of the British Renal Society Chronic Kidney Disease (CKD) Strategy Group. Bedrock Healthcare, a medical communications agency, has provided editorial support in developing the content; Janssen has reviewed the content for technical accuracy. Educational objectives: To provide clear and applicable clinical guidance on chronic kidney disease (CKD) in people with type 2 diabetes to primary care healthcare professionals To advise primary healthcare professionals on what people with diabetes need to know about their own condition with relation to CKD Usability objectives: To provide essential, relevant and up to date information in concise presentations To enable primary healthcare professionals to locate, select and use the content of the learning resource, as appropriate to their needs To enable secondary care experts in CKD to refer their primary care colleagues to the resource 1

3. Contents overview This learning resource comprises the following 10 sections (A-E): 2 Section A Introduction and overview of chronic kidney disease (CKD) in people with diabetes Section B Long-term impact of diabetes and the importance of optimal management of the condition Section C Pathophysiology of diabetic nephropathy & risk factors for the development of CKD Section D Appropriate monitoring for complications of diabetes in primary care – CKD as one of these complications Section EPrevention of diabetic kidney disease

4. Contents overview (cont.) This learning resource comprises the following 10 sections (F-J): 3 Section F Optimal management of diabetic kidney disease: hypertension and glycaemia Section G How to involve people with diabetes and CKD in their own care – what information must they have to manage their own condition effectively Section H What does the future hold for a person with well-managed diabetes and CKD? Section I What do the guidelines say and what do they mean in terms of the day-to-day management of CKD in people with diabetes? Section JSources of further information and reading list

5. Section J – key learning objective Direction to sources of further information on CKD in people with type 2 diabetes 4

6. Relevant guidelines KDIGO Guidelines 2012 http://www.kdigo.org/clinical_practice_guidelines/pdf/CKD/KDIGO_2012_CKD_GL.pdf http://www.kdigo.org/clinical_practice_guidelines/pdf/CKD/KDIGO_2012_CKD_GL.pdf NICE Type 2 Diabetes Guidelines (CG87 issued 2009, modified July 2014) http://www.nice.org.uk/guidance/cg87 http://www.nice.org.uk/guidance/cg87 NICE CKD Guidelines (CG182 issued July 2014) http://www.nice.org.uk/Guidance/CG182 http://www.nice.org.uk/Guidance/CG182 NICE: Acute Kidney Injury Guidelines 2013 http://guidance.nice.org.uk/CG/Wave24/10/Consultation/Latest http://guidance.nice.org.uk/CG/Wave24/10/Consultation/Latest UK Renal Association CKD Guidelines 2011 http://www.renal.org/docs/default-source/guidelines- resources/Detection_Monitoring_and_Care_of_Patients_with_CKD_- _Final_Version_28_February_2011.pdf?sfvrsn=0 http://www.renal.org/docs/default-source/guidelines- resources/Detection_Monitoring_and_Care_of_Patients_with_CKD_- _Final_Version_28_February_2011.pdf?sfvrsn=0 Management of hyperglycaemia in type 2 diabetes, 2015: A patient centred approach: Update to a Position Statement of the ADA and the EASD http://care.diabetesjournals.org/content/38/1/140.full.pdf 5 All websites last accessed on 14.1.15

7. Printed resources Understanding Chronic Kidney Disease – a guide for the non specialist: Robert Lewis, 2012, MK Publishing Oxford handbook of Renal Nursing: A Mahon, K Jenkins, L Burnapp, 2013, Oxford University Press Renal Nursing (4 th edition): N Thomas, 2014, John Wiley & Sons Ltd 6

8. Useful online resources Chronic Kidney Disease – A Guide for Primary Care www.ckdonline.org www.ckdonline.org British Renal Society CKD Strategy Group http://www.britishrenal.org/CKD-Forum.aspx http://www.britishrenal.org/CKD-Forum.aspx Renal Association http://www.renal.org http://www.renal.org Blood Pressure Association http://www.bpassoc.org.uk http://www.bpassoc.org.uk National Kidney Federation http://www.kidney.org.uk http://www.kidney.org.uk Primary Care Diabetes Society http://www.pcdsociety.org http://www.pcdsociety.org Diabetes UK professional site http://www.diabetes.org.uk/Professionals/ http://www.diabetes.org.uk/Professionals/ Janssen Diabetes Forum http://www.janssendiabetes.co.uk http://www.janssendiabetes.co.uk 7 All websites last accessed on 14.1.15

9. Section J – summary Our understanding of diabetic kidney disease and its management is evolving It is important to stay up-to-date to ensure your patients receive optimum treatment 8