1. OCULAR ONCOLOGY MICHAEL E GIBLIN FRANZCO

2. OSSN Ocular surface squamous neoplasia Encompasses conjunctival/corneal intraepithelial neoplasia (CIN) Squamous conjunctival dysplasia Carcinoma in situ Invasive squamous cell carcinoma (SCC)

3. Squamous cell carcinoma Extensive Ill defined edges Vascularised Corneal involvement

4. Conjunctival melanoma Primary aquired conjunctival melanosis (PAM) Preexisting conjunctival naevus De novo

5. PAM Primary acquired conjunctival melanosis Biopsy if: Growth Nodule formation Vascularity

6. De novo conjunctival melanoma

7. Rx Conjunctival SCC / Melanoma Excision / cryotherapy to cut conjunctival margin Topical Mitomycin C Episcleral plaque radiotherapy if recurrence

8. Iris melanoma

9. Congenital hypertrophy of the retinal pigment epithelium (CHRPE)

10. Choroidal neovascularisation: high myopia (Fuch’s spot)

11. Choroidal haemangioma

12. Melanocytic tumours of the posterior uvea Naevus Melanoma

13. Drusen Fibrous metaplasia of RPE Choroidal naevus

14. Uveal melanoma treatment Observation Tumours < 2mm thick

15. Symptoms Thickness > 2mm Orange pigment (lipofuscin) Growth Subretinal fluid Peripapillary location

16. Uveal melanoma treatment Observation Transpupillary laser thermotherapy (TTT) Posterior pole Thickness < 3.5mm

18. Uveal melanoma treatment Observation TTT Local resection Anterior to equator Base < 10mm

19. Uveal melanoma treatment Observation TTT Local resection Radioactive plaque therapy Thickness < 8mm Base <15mm

20. Ruthenium 106 Iodine 125

23. Uveal melanoma treatment Observation TTT Local resection Radioactive plaque therapy Proton beam/helium ion irradiation Gamma knife therapy

24. Uveal melanoma treatment Observation TTT Local resection Radioactive plaque therapy Proton beam/helium ion irradiation Gamma knife therapy Enucleation Base > 15mm

25. Metastatic tumours Breast / lung carcinoma Amelanotic Multifocal Choroidal Treat only if sight affected

26. Amelanotic Multifocal Choroidal Posterior to equator

28. M AG ICMI KETHE MEDICI NEMAN