1. Reports due Th 10/21 or M 10/25 Today: Patents

2. Funding idea could ease ‘Valley of Death’ Early funding for technology may increase success rates The Daily Texan Sept 15, 2010

3. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 UT’s new chief commercialization officer inherited a commercialization operation that faces lackluster intellectual property revenue and a competitive period between patenting and commercialization that consumes many technologies before they even launch into the market.

4. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 But Richard Miller, a former biotech entrepreneur from Silicon Valley, said he has a new idea for UT — the University should fund researchers while they look for license partners in the early stages of development and ensure that venture capitalists get involved in UT research.

5. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 In the 2010 fiscal year, which ended Aug. 31, UT researchers submitted about 180 inventions to the Office of Technology Commercialization, which then filed about 300 patents. This year, 32 of those patents attained third-party licenses

6. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 Most patents in the office come from pharmaceuticals, physical and life sciences, computer and nanosciences, and engineering — for example, Toyota funded research on a car- crash predicting mechanism invented by computer science professor Risto Miikkulainen.

7. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 UT's intellectual property revenue has risen steadily since 2003. UT spent $640 million on research in fiscal year 2010, the University accumulated only about $14 million in revenue. In 2008, the U. of Utah invested more than $270 million in research and generated $26 million in patent revenue, U. Wisconsin earned $56 million UT invested more than $520 million and generated $11 million

8. Funding idea could ease ‘Valley of Death’ The Daily Texan Sept 15, 2010 Craig Heim, licensing manager at the Wisconsin Alumni Research Foundation, the University of Wisconsin at Madison’s commercialization arm, said, “Large companies have slashed their research and development budgets and are interested in more mature, developed technologies.”

9. versus What is the purpose of public research? Basic Research Technology Factory

10. Can you own an idea?

11. Would you share your idea if others will profit from it?

12. Can you own an idea? Would you share your idea if others will profit from it? Would you accept someone else taking credit for your idea(s)?

13. Patents give 20 year monopoly for inventor www.uspto.gov

14. Three types of U.S. patents: 1) Utility patents may be granted to anyone who invents or discovers any new and useful process, machine, article of manufacture, or composition of matter, or any new and useful improvement thereof; 2) Design patents may be granted to anyone who invents a new, original, and ornamental design for an article of manufacture; and 3) Plant patents may be granted to anyone who invents or discovers and asexually reproduces any distinct and new variety of plant. www.uspto.gov

15. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Patentable inventions must be: Useful New or Novel –Non-obvious

16. The patent application must include sufficient information for someone “practiced in the art” to apply the patent.

17. http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7,445,235.PN.&OS=PN/7,445,235&RS=PN/7,445,235 United States Patent number 7,445,235 by Makabe et al. issued on November 4, 2008

18. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Patents give right to exclude others from making, selling, and/or using the invention. Patents are considered personal property and may be sold, licensed, etc.

19. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Patents must be filed within 1 year of initial disclosure. In the U.S. a patent can be nullified if another can prove prior invention.

20. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Patent application may take from 1-5+ years Only registered patent attorneys or agents may represent a patent holder to the patent office.

21. Who owns your data?

22. UT Employers generally own their employees data.

23. Employers often receive a royalty-free license to a patent. Funding agencies also often have rights to patent licenses.

24. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. As public funding levels decrease, there is pressure on public institutions (universities and researchers) to seek alternate sources of funding. Patenting discoveries provides a possible revenue source.

25. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Does patenting of DNA sequencing impede research or increase research by adding a profit motive?

26. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. Protection of intellectual property was guaranteed in the U.S. Constitution (1787). The 1980 U.S. Supreme Court ruling (Diamond v. Chakrabarty) allowed patents for nonhuman life forms if there was human intervention in their creation.

27. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. A 1998 patent application for human-animal chimera cells was rejected on the grounds of being immoral and too human. For more info see: http://www.pbs.org/newshour/bb/science/july- dec05/chimeras_newman-ext.html

28. Scientific Integrity: an Introductory Text with Cases, 2nd ed. (2000) Marcina, F. L. ASM Press, Washington, D.C. A 1998 patent application for human-animal chimera cells was rejected on the grounds of being immoral and too human. Many patents have been issued with cells containing human genes. How much human DNA makes a human?

29. Examples of current patents: Atryn- antithrombin produced in transgenic goats (in milk) has anti-clotting properties

30. Examples of current patents: Atryn- antithrombin produced in transgenic goats (in milk) has anti-clotting properties Evolutec has patents on proteins in tick saliva for use as anti-inflammatory

31. Examples of current patents: Atryn- antithrombin produced in transgenic goats (in milk) has anti-clotting properties Evolutec has patents on proteins in tick saliva for use as anti-inflammator GTG in Australia has patents on non-coding human DNA for detecting risk of various diseases

32. Neem, say the women, helps babies sleep, keeps flies away, is a cosmetic, a disinfectant and a pesticide. Its leaves make good cattle fodder, its twigs are good for teeth and gums. It is used, they say, for snake bites, malaria, hysteria, high blood pressure, pain relief, skin diseases and a host of other ailments. Over 70 U.S. patents for use of Indian neem tree

33. Neem, say the women, helps babies sleep, keeps flies away, is a cosmetic, a disinfectant and a pesticide. Its leaves make good cattle fodder, its twigs are good for teeth and gums. It is used, they say, for snake bites, malaria, hysteria, high blood pressure, pain relief, skin diseases and a host of other ailments. Over 70 U.S. patents for use of Indian neem tree One was rejected due to previous use in indigenous Indian culture

34. Concerns of developing nations vs. industrialized countries Bioprospecting

35. U.S. patent issued on cell line developed from indigenous 21 year old from New Guinea. Possible use in treating leukemia, NIH researchers listed as inventors.

36. Reports due Th 10/21 or M 10/25 Next: Who are you? http://www.thehouseoftorment.com