1. N5 Biology Cell Biology subunit 3 DNA and Making New Cells

2. Making New Cells simple cell division diagram nucleus membrane

3. Specieschromosome complement Number of matching pairs human46 fruit fly8 snail54 cabbage18 23 4 27 9

4. centomere chromatids Duplicated chromosome

5. Stages of Mitosis Click here for mitosis animation http://www.cellsalive.com/mitosis.htmhttp://www.cellsalive.com/mitosis.htm

6. Click here for Time lapse film of mitosis (1.30 mins) http://www.bbc.co.uk/learningzone/clips/cell-division-by- mitosis/4189.html http://www.bbc.co.uk/learningzone/clips/cell-division-by- mitosis/4189.html More Mitosis Animations Click here for you Tube video (10 mins) http://www.youtube.com/watch?feature=player_emb edded&v=L0k-enzoeOM#! http://www.youtube.com/watch?feature=player_emb edded&v=L0k-enzoeOM#!

7. When the chromosomes become visible they appear as double threads called chromatids joined by a centromere. Structures in the cell called centrioles migrate to opposite ends of the cell - the ‘north and south poles’. The membrane round the nucleus disintegrates and the chromosomes line up along the equator – in between the north and south poles. Spindle fibres from the centrioles attach to the centromere of each chromosome. The spindle fibres shorten and pull the chromatids apart. One chromatid from each pair moves to the north pole and the other one moves to the south pole. Two new nuclei form when the nuclear membrane forms round each set of chromatids – now called chromosomes. The cell then divides in two Stages of Mitosis text from pupil booklet

8. Looking at Dividing Cells You may see some cells under the microscope like some of the cells below

9. Looking at Dividing Cells

10. Cell production Click here for film showing how new skin cells are grown (3.09 mins) http://www.bbc.co.uk/learningzone/clips/growing-new-skin-cells/111.html http://www.bbc.co.uk/learningzone/clips/growing-new-skin-cells/111.html Click here to see a Youtube film of AsepticTechniques while transferring culture medium from a bottle to an agar plate (only watch from start to 6 mins) http://www.youtube.com/watch?v=gQvZ4opDcno&feature=player_embedde d http://www.youtube.com/watch?v=gQvZ4opDcno&feature=player_embedde d

11. Aseptic Technique technique reason heat glassware in an autoclave (pressure cooker) to 121 o C wash hands before and after experiment hold lid over open petri dish flame innoculating loop lids held onto inoculated petri dishes with tape surfaces disinfected before and after experiment sterilise equipment kill microbes on work area prevent entry of unwanted microbes destroy unwanted microbes on wire prevent entry OR exit of microbes from agar remove microorganisms from skin

12. DNA and Genes A determines an organisms characteristics. Genes are found on. Chromosomes are found in the of all cells. Chromosomes are threadlike structures made from. DNAnucleichromosomes gene chromosomes nuclei DNA

13. weak hydrogen bond deoxyribose sugar double stranded DNA nucleotide base phosphate strong chemical bond DNA Structure

14. Click here for website with template and instructions for origami DNA model http://www.dnai.org/teacherguide/guide.html Finished product should look like this

15. DNA discovery Click here for Youtube video http://www.youtube.com/watch?v=7yE3Z5f- 7i0&feature=player_embedded#! DNA: The secret of life, a programme about the race to uncover the structure of DNA. Contains interviews from the scientists involved in the discovery (53mins) Click here for DNA Timeline Activity http://www.dnai.org/teacherguide/guide.html http://www.dnai.org/teacherguide/guide.html