1. Originally presented to: 2005 BIRN Executive Committee Meeting January 25, 2005 Breckenridge, Colorado BIRN-GCRC 2004 Integration Efforts

2. 2004 Chronology of Events  NCRR Integration Interests  GCRC – “Working Group” Formation; 30 Centers (GCRCs & Imaging Cores) Planning; teleconference calls Online survey

3. GCRC Working Group  Brigham & Women’s (BGH)  Duke  Mass General (MGH)  Ohio State  Stanford  UCLA  UCSD  U of Iowa  U of Minnesota  U of N. Carolina  U of N. Mexico  Wash. St. Louis  Cal. Inst. Tech.  U of CO - Pediatric  UCLA – Harbor  Northwestern  U of Maryland  U of Connecticut  Vanderbilt  UC – Irvine  Yale  UT – San Antonio  U of Miami  U of Michigan  Mt. Sinai  North Shore Long Island  U of Pittsburgh  Medical College of WI  Cleveland Clinic

4. Next  BIRN 2004 All-Hands Meeting in Boston ~ 15 Participating GCRCs Good information exchange Pilot project discussion 11 Potential projects at 6 Centers

5. Next  BIRN-GCRC Integration Team Members  Elaine Collier – NCRR/NIH  Bob DiLaura – GCRC  Jorge Jovicich - BIRN  Jessica Turner - BIRN  Vicky Rowley - BIRN Developed pilot project selection criteria to benefit BIRN & GCRC Narrow list of possible projects to 5

6. Selection Criteria  Write-up clarity; quality?  Human organ?  Imaging modality?  BIRN collaboration at site?  Mutual benefits to GCRC and BIRN?  Generalizable outside of that GCRC site?  Applicable to GCRC research?  Feasibility with current resources?  Can it be done within one year (i.e., pilot)?  Can it be presented by the 2005 meeting?  Is it repetitious with another project?  Is it good science; add value to research?

7. “Big Picture” Going Forward BIRN GCRC Timeline January 2005 Pilot Phase AHM Phase 1 review, evaluation and decision point *GCRC annual meeting progress report due 4/28/05 Planning Phase BIRN network/ tools available & used in GCRC studies Rollout

8. Q1-2 in 2005+  What?  When?  Where?  How?  Who? Leadership; legwork; oversight; project management; resources; etc.