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L-Measure: a software tool for the analysis of neuronal morphology… …and its application to hippocampal pyramidal cells.

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Presentation on theme: "L-Measure: a software tool for the analysis of neuronal morphology… …and its application to hippocampal pyramidal cells."— Presentation transcript:

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2 L-Measure: a software tool for the analysis of neuronal morphology… …and its application to hippocampal pyramidal cells.

3 L-MEASURE: MORPHOMETRIC ANALYSIS OF NEURONAL TREES Why dendritic morphology? The study of dendritic morphology is a key to correlate neuronal structure, activity, and function. Sridevi Polavaram*, Ruggero Scorcioni, Giorgio A. Ascoli: Krasnow Institute for Advanced Studies Bifurcation angle … Branch length Real dendrite http://www.krasnow.gmu.edu/ascoli/CNG/ George Mason University

4 L-MEASURE: MORPHOMETRIC ANALYSIS OF NEURONAL TREES Sridevi Polavaram*, Ruggero Scorcioni, Giorgio A. Ascoli: Krasnow Institute for Advanced Studies George Mason University spolavar@gmu.edu http://www.krasnow.gmu.edu/ascoli/CNG/ Sample Output

5 Quantitative morphometry of reconstructed hippocampal pyramidal cells: Differences between anatomical subregions and reconstruction laboratories. Ruggero Scorcioni 1 (rscorcio@gmu.edu), MT Lazarewicz 2, GA Ascoli 1rscorcio@gmu.edu 1 :George Mason University 2 : University of Pennsylvania

6 http://www.krasnow.gmu.edu/ascoli/CNG/ CA3 CA1 CA3 CA1 rscorcio@gmu.edu


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