1. Drugs for Diabetes Mellitus
ESAT 4001

2. Diabetes
Type I
Type II

3. Management of Diabetes
Glucose monitoring
Diet and Exercise

4. Insulin Administration
Synthesized from recombinant DNA
Absorption rate tied to injection site
Recommended that injection site remain same day to day
Controls insulin reactions
Avoid injecting into exercising muscles
Abdomen works well in exercising population

5. Insulin Storage and Inspection
Room temperature
Refrigerated after opened and not in use
Visually inspect prior to use
Clumping, frosting, precipitation, or color changes may = loss of potency

6. Insulin Injection Devices
Syringe
Insulin pump
Prefilled insulin pen

7. Insulin Types Rapid-acting Short-acting Intermediate-acting
Long-acting

8. Insulin Types and Actions

9. Adverse Effects Hypoglycemia Diabetic Ketoacidosis Lipohypertrophy
Lipoatrophy
Local skin reaction

10. Oral Antidiabetic Agents
Type II diabetes
Exercise and diet changes first
Used if lifestyle modifications fail

11. Oral Antidiabetic Agents