1. 2003-2004 Hematopoiesis Pharmacology Review 28 August 2015 7:22 AM

2. Abciximab Antiplatelet Anti-GPIIb/IIIa receptor antibody

3. Acetaminophen Analgesic, Antipyretic

4. Adalimumab TNF inhibitor Anti-TNF antibody Used in rheumatoid arthritis

5. Alemtuzumab Antineoplastic Anti-CD52 antibody

6. Allopurinol Antigout Antineoplastic (supporting agent) Folic acid analogue Xanthine oxidase inhibitor

7. Aminocaproic acid (EACA) Procoagulant Inhibitor of plasminogen activation (decreases fibrinolysis)

8. Aminoglutethimide Antineoplastic Immunosuppressive Glucocorticoid antagonist Aromatase inhibitor (decreases steroid synthesis)

9. Angiostatin Antineoplastic Angiogenesis inhibitor

10. Anistreplase Thrombolytic Streptokinase + plasminogen

11. Anti-thymocyte globulin Immunosuppressive Anti-T cell antibody

12. Aprotinin Procoagulant Fibrinolytic inhibitor Serine protease inhibitor (“serpin”) Streptokinase inhibitor

13. Argatroban Anticoagulant Direct thrombin inhibitor

14. L-asparaginase Antineoplastic Protein synthesis inhibitor

15. Aspirin (Acetylsalicylic acid, ASA) NSAID (acetylsalicylate) Analgesic, Anti-inflammatory Antipyretic, Antiplatelet Irreversible cyclooxygenase inhibitor

16. Azathioprine Immunosuppressive Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP)

17. Basiliximab Immunosuppressive Anti-CD25 (interleukin 2 receptor) Organ transplant (antirejection)

18. Betamethasone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation

19. Bivalirudin Anticoagulant Direct thrombin inhibitor

20. Bortezomib Antineoplastic Proteosome inhibitor

21. Bradykinin Inflammatory mediator Plasma, hypotension, pain

22. C3a, C5a Inflammatory mediators Anaphylatoxins Low molecular weight complement cleavage products

23. Celecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

24. Cetirizine Antihistamine H 1 antagonist Non-sedating

25. Chlorpheniramine Classical antihistamine H 1 antagonist

26. Clopidogrel Antiplatelet ADP receptor antagonist

27. Cobalamin (cyanocobalamin, hydroxocobalamin) Vitamin Treatment for vitamin B12 deficiency

28. Cortisol (Hydrocortisone) Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid

29. Cyclosporine Immunosuppressive Antineoplastic Binds cyclophilin Inhibits calcineurin

30. Cytarabine (AraC) Antineoplastic Antimetabolite

31. Daclizumab Immunosuppressive Anti-CD25 (interleukin 2 receptor) antibody Organ transplant (anti-rejection)

32. Dalteparin Anticoagulant LMW Heparin ATIII activator

33. Desmopressin acetate Synthetic analogue of arginine vasopressin Used in treatment of bleeding disorders

34. Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Antiemetic Anti-inflammatory steroid Not by inhalation

35. Diflunisal NSAID Analgesic, Anti-inflammatory Antipyretic Cyclooxygenase inhibitor

36. Diphenhydramine Classical antihistamine Antiemetic H 1 antagonist

37. Dipyridamole Antiplatelet Phosphodiesterase inhibitor (increases cAMP)

38. Drotrecogin alfa (Activated Protein C) Anticoagulant Many actions Treatment for septic shock

39. Edrecolomab Antineoplastic Anti-17-1A antibody

40. Enoxaparin Anticoagulant LMW Heparin ATIII activator

41. Eptifibatide Antiplatelet GPIIb/IIIa antagonist

42. Erythropoietin (EPO) Cytokine Primary regulator of RBC synthesis

43. Etanercept TNF inhibitor Tumor necrosis factor receptor + F c portion of IgG Used in rheumatoid arthritis

44. Fexofenadine Antihistamine H 1 antagonist Non-sedating

45. 5-Fluorouracil Antineoplastic Antimetabolite Thymidylate synthase inhibitor

46. Folic acid Vitamin Treatment for folic acid deficiency

47. Gefitinib Antineoplastic Miscellaneous Tyrosine kinase inhibitor

48. Gemcitabine Antineoplastic Antimetabolite

49. Gemtuzumab Antineoplastic Anti-CD33 antibody

50. Heparin Anticoagulant ATIII activator

51. Hirudin Anticoagulant Direct thrombin inhibitor (DTI)

52. Histamine Inflammatory mediator Stored in mast cells and basophils

53. Hydrocortisone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid

54. 4-Hydroxycoumarin Oral anticoagulant Vitamin K synthesis inhibitor

55. Hydroxyurea Antineoplastic Miscellaneous Ribonucleotide reductase inhibitor

56. Hydroxyzine Classical antihistamine H 1 antagonist

57. Ibritumomab Antineoplastic Anti-CD20 antibody

58. Ibuprofen NSAID Analgesic, Anti-inflammatory Antipyretic Reversible cyclooxygenase inhibitor

59. Imatinib Antineoplastic Miscellaneous Tyrosine kinase inhibitor

60. Indomethacin NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor Tocolytic Uterine relaxant

61. Infliximab TNF inhibitor Anti-TNF monoclonal antibody Treatment of IBD

62. Interferon alpha Antiviral for hepatitis Antineoplastic Cytokine Anti-angiogenesis

63. Interleukin 2 Cytokine Antineoplastic

64. Interleukin 11 Cytokine Antineoplastic (supporting agent)

65. Interleukin 12 Cytokine Antineoplastic (supporting agent)

66. Kallidin Inflammatory mediator Plasma, hypotension, pain

67. Ketoprofen NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

68. Lepirudin Anticoagulant Direct thrombin inhibitor (DTI)

69. Leucovorin Antineoplastic (supporting agent) Folic acid analogue (used in methotrexate rescue)

70. Leukotriene B 4 (LTB 4 ) Inflammatory mediator Lipoxygenase product of arachidonate metabolism Chemotactic

71. Leukotrienes C 4, D 4, E 4 (LTC 4, LTD 4, LTE 4 ) Inflammatory mediators Cysteinyl leukotrienes Peptidyl leukotrienes SRS-A Lipoxygenase products of arachidonate metabolism

72. Loratidine Antihistamine H 1 antagonist Non-sedating

73. Meclofenamate NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

74. 6-Mercaptopurine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

75. Methotrexate Immunosuppressive Antineoplastic Folic acid antagonist Dihydrofolate reductase inhibitor

76. Methylprednisolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Not by inhalation

77. Montelukast Leukotriene inhibitor LTR1 and LTD4 antagonist Asthma treatment

78. Muromonab-CD3 Immunosuppressive Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)

79. Mycophenolate Immunosuppressive Inhibits inosine monophosphate dehydrogenase activity

80. Naproxen NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

81. Non-steroidal Anti-inflammatory Drugs (NSAIDs) Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitors

82. Omalizumab Anti-asthma Anti-IgE antibody

83. Palivizumab Antiviral Monoclonal antibody against the surface of respiratory syncytial virus

84. Pentostatin Antineoplastic Miscellaneous Enzyme inhibitor (blocks purine synthesis)

85. Phytonadione Vitamin K Warfarin antagonist

86. Piroxicam NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

87. Platelet Activating Factor (PAF) Inflammatory mediator Lipid Hypotensive

88. Prednisone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory Not by inhalation

89. Promethazine Classical antihistamine Antipsychotic Antiemetic H 1 antagonist

90. Prostaglandin D 2 (PGD 2 ) Bronchoconstrictor Cyclooxygenase product of arachidonate metabolism

91. Prostaglandin E 2 (PGE 2 ) Dinoprostone (Dinoprost) Oxytocic prostaglandin Inflammatory mediator Cyclooxygenase product of arachidonate metabolism Uterine stimulant Cervical ripener

92. Prostaglandin F 2 (PGF 2 ) Inflammatory mediator Cyclooxygenase product of arachidonate metabolism

93. Prostaglandin I 2 (PGI 2 ) Inflammatory mediator Inhibits platelet aggregation Cyclooxygenase product of arachidonate metabolism Prostacyclin

94. Protamine Sulfate Heparin antagonist

95. Rituxumab Antineoplastic Anti-CD20 antibody

96. Rofecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

97. Sargramostim (GM-CSF) Colony stimulating factor WBC (granulocyte and macrophage) stimulant

98. Sirolimus Immunosuppressive Binds FKBP, inhibits mTOR (mammalian kinase target of rapamycin) & cell cycle progression Rapamycin

99. Streptokinase Thrombolytic

100. Sulindac NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

101. Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

102. Thalidomide Antineoplastic Leprosy treatment Anti-angiogenic Anti-TNF 

103. 6-Thioguanine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

104. Thromboxane A 2 (TXA 2 ) Autacoid Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

105. Ticlopidine Antiplatelet ADP receptor antagonist

106. Tissue plasminogen activators Thrombolytics alteplase, reteplase, tenecteplase

107. Tositumomab Antineoplastic Anti-CD20 antibody

108. Trastuzumab Antineoplastic Anti-HER2 antibody

109. Tripelennamine Classical antihistamine H 1 antagonist

110. Tumor necrosis factor  Cytokine Antineoplastic

111. Urokinase Thrombolytic

112. Warfarin Anticoagulant Vitamin K synthesis inhibitor

113. Zafirlukast Leukotriene inhibitor LTR 1 and LTD 4 antagonist Asthma treatment

114. Zileuton Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma