Presentation on theme: "Wake-up 1.A woman carrying hemophilia marries a man who is a hemophiliac. What percentage of their children will have hemophilia? 1.Cross a man heterozygous."— Presentation transcript:
Wake-up 1.A woman carrying hemophilia marries a man who is a hemophiliac. What percentage of their children will have hemophilia? 1.Cross a man heterozygous B with a woman who is a purebred for A. What blood types will their children have?
Wake-up 1.How would you recognize an individual with Trisomy 16? 2.What would be the notation for a female with Trisomy 16? 3.Explain the difference between autosomes and sex chromosomes.
Human Genetic Disorders and Pedigrees Christopherson
Human Genetics: Karyotypes 46 TOTAL 23 homologous pairs 46 TOTAL 23 homologous pairs
Sex Chromosomes 2 sex chromosomes Typical Female = XX Typical Male = XY
Autosomes Autosomes: Any chromosome that’s not a sex chromosome 44 Autosomes 22 pairs of Autosomes
Recessive Disorder Caused by 2 recessive alleles
Albinism Defect of melanin production that results in little or no color in the skin, hair, and eyes
How does it happen? How does it happen? Affected Genotype: aa
Cystic Fibrosis Disease that causes the body to produce unusually thick, sticky mucus that: Clogs the lungs and leads to lung infections Obstructs the pancreas Stops natural enzymes from helping the body break down and absorb food
How does it happen? How does it happen? Affected Genotype: HH or Hh
Sex-Linked Disorder Linked to sex chromosomes Recessive Disorders – caused by recessive alleles
Color Blindness Inability to see colors in the normal way
How does it happen? Affected Genotypes: X b X b X b Y
Hemophilia Inability of the blood to clot properly
How does it happen? Affected Genotypes: X h X h X h Y
Wake-up 1.A parent has a genotype Bb. What alleles can this parent give their children? 1.A woman carrying colorblindness marries a normal male. What are the chances of producing a colorblind child? 2.How many alleles do you get from your parents (Dad and Mom)?
What is a Pedigree??? Diagram showing a family tree and patterns of inheritance.