2. Generic nameTherapeutic dose range RisperidoneAcute mania: usual dose 2-6mg/day OlanzapineAcute mania: 5-20mg/day Maintenance: continue at dose used for acute episode Quetiapine( Seroquel)Acute mania: usual dose 200- 800mg/day Titrated to average of 600mg/day ZiprasidoneAcute mania: 80-160mg/day SSRIs/tricyclicsAcute bipolar depression: equivalent doses to those used in treating major depression

3. Generic nameTherapeutic dose range LithiumAcute mania: 400-1200 mg/ day Maintenance : reduce dose to maintain blood level within therapeutic range (0.6-0.8mmol/L) Lamotrigine*Acute bipolar depression: 100- 400mg/day titrated upwards slowly CarbamazepineAcute mania: 400-1200mg/day, titrated gradually Maintenance: 200-400mg/day Sodium valproateAcute mania: can consider rapid titration Maintenance: usually 1000- 2000mg/day, divided doses, titrated gradually