1. Chapter 24: Development

2. Chapter 24.1: Embryonic Period

3. First Week of Development -Fertilization -Can occur during a 3-day window -Early Embryonic Development -Rapid cell division -Development of inner cell mass and trophoblast -Blastocyst implants into uterine wall

4. Frontal plane 1. Fertilization (occurs within uterine tube 12–24 hours after ovulation) 2. Cleavage (first cleavage completed about 30 hours after fertilization) 3. Morula (3–4 days after fertilization) 4. Blastocyst (4 1 / 2 –5 days after fertilization) Uterine cavity 5. Implantation (occurs about 6 days after fertilization) Uterus Endometrium Myometrium Ovulation Ovary Frontal section through uterus, uterine tube, and ovary

5. Second Week of Development -Trophoblast penetrates uterine wall and continues to grow -Human chorionic gonadotropin (hCG) sustains progesterone and estrogen secretion -Inner cell mass develops into amniotic cavity and yolk sac -Extraembryonic mesoderm begins placenta formation Amniotic cavity Formation of yolk sac Extraembryonic mesoderm

6. Third Week of Development -Gastrulation: formation of three primary germ layers -Ectoderm -Mesoderm -Endoderm -Mesodermal cells develop into notochord -Neural tube becomes brain and spinal cord

7. Third Week of Development Umbilical vein Umbilical arteries Maternal blood Amniotic cavity Embryo Yolk sac

8. Fourth-Eighth Weeks -All major organs and body systems begin to develop -Embryo triples in size and becomes three- dimensional (embryonic folding) 20-day embryo 24-day embryo 32-day embryo 44-day embryo 52-day embryo

9. Chapter 24.2-Fetal Period

10. Fetal Development -Very few new structures appear and rate of body growth is very fast -Fetus is less vulnerable to drugs, radiation, and microbes 10-week fetus 13-week fetus 26-week fetus