1. Division of AIDS, Behavioral and Population Sciences Risk, Prevention and Health Behavior IRG August, 2014 Reorganization/Realignment of RPHB Addictive Behavior Study Sections

2.  In 2010, the Risk, Prevention and Intervention for Addictions Study Section (RPIA) began to receive over 150 applications per round. An “Overflow” panel (RPIA- N) was set up, and has been in operation for the past 4 years. RPIA and RPIA-N have each been reviewing around 60-80 applications every round consistently  Use of RPIA-N as an overflow panel (with own percentile base) results in less transparency to investigators  Identical expertise and scoring behavior are expected for the two panels, but this has proven difficult to maintain  Continuation of RPIA-N is unsustainable – a second addictive behavior study section needs to be chartered Background and Rationale

3.  Understanding Addictive Behavior (Understanding)  What is it?  Preventing and Treating Addictive Behavior (Intervening)  What can we do about it? Proposal for Two Addictive Behavior Study Sections by Content Division

4.  Risk factors predicting onset, development, progression of addictions (longitudinal)  Prevalence, nature (survey, secondary analysis)  Characteristics (group comparison)  Effects of drugs and addictive behaviors (lab studies of drug effects, cognition, etc.)  Effects of society and policies on addictive behaviors (e.g., effects of marijuana legalization on drug use initiation)  Development/testing of tools/methods for understanding addictive behaviors Understanding

5.  Testing prevention interventions (clinical trials; e.g., RCT, adaptive designs)  Testing treatment interventions (clinical trials; e.g., RCT, adaptive designs)  Testing intervention delivery methods  Evaluating implementation or marketing of interventions (health services)  Evaluating regulatory policy as an intervention (e.g., smoking bans)  Development and preliminary testing of interventions (pilot) Intervening

6.  Historical data (past four rounds), in terms of number of applications, support the rationale to establish two study sections by content division: Understanding vs. Intervening  Reliability test by independent coders resulted in 93% agreement on the division of applications Analysis of RPIA/RPIA-N Applications: Distribution of Applications by Proposed Content Division

7.  Applications submitted to NIDA are evenly distributed across the two content areas  There is a critical mass of NIAAA applications in “Understanding” and a critical mass of NCI applications in “Intervening” Analysis of RPIA/RPIA-N Applications: Content Division and Funding ICs

8. Lisa Marsch, Ph.D. (Former RPIA Member) Associate Professor Dartmouth Psychiatric Research Center Christi Patten, Ph.D. (Current RPIA Chair) Professor Department of Psychiatry and Psychology, Mayo Clinic Steven Schinke, Ph.D. (Former RPIA Chair) D’Elbert and Selma Kennan Professor School of Social Work, Columbia University Robert Schnoll, Ph.D. (Former RPIA Chair) Associate Professor Department of Psychiatry, University of Pennsylvania Eric Strain, M.D. (Current RPIA-N Chair) Professor Department of Psychiatry, Johns Hopkins University School of Medicine Leading Scientists In Addictive Behavior Research Karyl Swartz, Ph.D. Director, DABP, CSR Weijia Ni, Ph.D Chief, RPHB, DABP, CSR Kristen Prentice, Ph.D. SRO, RPIA-N Miriam Mintzer, Ph.D. SRO, RPIA CSR Staff Redonna Chandler, Ph.D. Acting Director, DESPR, NIDA Joseph Frascella, Ph.D. Director, DCNBR, NIDA Elizabeth Ginexi, Ph.D. Program Director, TCRB, BRP, NCI Michael Hilton, Ph.D. Associate Director, DEPR, NIAAA William Klein, Ph.D. Associate Director, BRP, NCI Ivan Montoya, M.D., M.P.H. Deputy Director, DPMCDA, NIDA NIH/IC Program Staff Working Group Participants

9.  Two WG meetings: April 9, 2014 and July 30, 2014  Stakeholders from NIH Institutes and Scientific Community participated (See List)  Advantages of the proposal for the two study sections :  More transparency  More consistency and equity  Greater likelihood of specific expertise  Less competition for reviewers  Minor edits to specific content division areas  Unanimous support for process and proposal Working Group Discussion Summary

10.  August 2014: Guidelines developed for the two study sections: “Understanding”  Addiction Risks and Mechanisms (ARM); “Intervening”  Interventions to Prevent and Treat Addictions (IPTA).  September 2014: Approved by CSR Senior Staff  October 2014: Present to CSR Advisory Council  January 2015: Submit slates of both study sections for approval  February 2015: Public Announcement of Committees for June/July submission  October 2015: First review meetings of both study sections  Post-implementation: Regular monitoring will be conducted and guidelines adjusted as needed Next steps