1. The following pages provide supplemental information about the programs of studies in chemistry

2. Programs of Studies in Chemistry Specialist Programs Chemistry Specialist Biological Chemistry Specialist Chemical Physics Specialist Environmental Chemistry Specialist Materials Chemistry Specialist Synthetic and Catalytic Chemistry Specialist Major/Minor Programs Chemistry Major Chemistry Minor Environmental Chemistry Minor Nanoscience Minor

3. Chemistry Specialist

4. Broad coverage in core areas of chemistry plus introductory courses in mathematics and physics. Flexible requirements in 3rd and 4th Year course requirements allows students to tailor their course choices. Suitable for professional work in any area of chemistry and for entry into graduate school.

5. Chemistry Specialist Covers research areas not covered by other specialty programs: Organic and Inorganic Synthesis Organometallic Chemistry & Catalysis Medicinal & Pharmaceutical Chemistry Analytical Chemistry Molecular Devices

6. Chemistry Specialist: Requirements Consult: Associate Chair, Undergraduate Studies This specialist program requires completion of 14 Full Courses, including the following courses: First Year: CHM151Y (strongly recommended) or CHM138H/139H MAT135Yor MAT137Y PHY(131H, 132H) or PHY(151H, 152H)

7. Chemistry Specialist: Requirements Physical - CHM326H or CHM328H Experimental Physical - CHM327H Further 300/400-level course equivalents in CHM/MAT/another science, including at least three of: Analytical - CHM317H Inorganic - CHM338H Organic - CHM343H Biomolecular - CHM379H Analytical Environmental – CHM410H Introduction to Research – CHM499Y, and at least three 400-level CHM full course equivalents 3rd / 4th Year: Analytical - CHM217H Physical - CHM225Y or (CHM220H min grade B and CHM221H) Inorganic - CHM238Y Organic - CHM249H (strongly recommended) or CHM247H Calculus II - MAT235Y or MAT237Y Biochemistry – BCH210H Second Year:

8. Specialist in Biological Chemistry What is it? The study of the chemistry of biological systems. Nature at the atomic and molecular level. CO 2 + H 2 0 HCO 3 - + H + BiochemistryBiological Chemistry CellPathwayBiomoleculeAtoms For example: Biological catalysis, biosynthesis, protein switching, receptors, carbohydrate chemistry, genetic regulation, bioinorganic chemistry, chemical genetics, signaling, transport

9. Why? Understand how nature works at the molecular level. Manipulate biomolecules to design new systems. What next? Graduate school - chemistry, biochemistry, biophysics, pharmacy Professional schools – medicine, law, dentistry, pharmacy, business Biotech Industry Pharmaceutical Industry Academics - Universities, primary and secondary education Government labs, public policy Science journalism Consulting How? Cellular biology, molecular biology,genetics, protein chemistry, spectroscopy, analytical chemistry, structural biology, biochemistry, organic synthesis, biophysics Specialist in Biological Chemistry

10. 1st Year BIO(120H, 130H), CHM151Y/(138H/139H), MAT135Y/137Y, PHY(131H,132H)/(151H,152H) 2 nd Year BIO250Y/(240H, 241H)Cellular and Molecular Biology CHM225Y/(220H, 221H)Introduction to Physical Chemistry CHM238YIntroduction to Inorganic Chemistry CHM249H Organic Chemistry BCH210HIntroductory Biochemistry CHM217H Introduction to Analytical Chemistry Plus half credit MAT/CSC/STA course 3 rd Year CHM347H Organic Chemistry of Biological Compounds CHM348H Organic Reaction Mechanisms CHM379H Techniques in Biological Chemistry 4 th Year CHM437H Bio-Inorganic Chemistry CHM447H Bio-Organic CHM479H Biological Chemistry Specialist in Biological Chemistry

11. CHM325H – Materials Chemistry CHM342H – Modern Organic Synthesis CHM343H – Organic Synthesis Laboratory CHM338H – Intermediate Inorganic Chemistry PHC320H – Medicinal Chemistry CHM440H – Synthesis of Modern Pharmaceutical Agents CHM441H – Applications of Spectroscopy to Organic Structure Determination CHM443H – Physical Organic Chemistry CHM499Y – Introduction to Research in Chemistry CHM310H – Environmental Chemistry CHM317H – Introduction to Instrumental Methods of Analysis BCH304H – Cell Dynamics & Interactions CHM417H – Laboratory Instrumentation CHM443H – Physical Organic Chemistry CHM499Y – Introduction to Research in Chemistry BCH425H – Structural Biology: Principles & Practice CSB450H – Plant Proteomics & Metabolomics medicinal/pharmaceutical chemistry: bioanalytical chemistry: Specialist in Biological Chemistry And maybe…… Or….

12. Ron Kluger - Enzyme-coenzyme catalysis mechanisms - Protein modification, hemoglobin Andrew Woolley- Photo-control of peptide and protein conformations - Fluorescent studies on membrane channel formation Jumi Shin- Directed evolution and design of DNA-binding proteins Deborah Zamble- Bioinorganic chemistry - Metalloenzyme biosynthesis, metal homeostasis Mark Nitz- Fluorescent methods to study sulfated carbohydrates - Chemoenzymatic synthesis Specialist in Biological Chemistry

13. Chemical Physics Specialist What is chemical physics? Chemical Physics can be characterized as the quest to lay bare the underlying basic explanations of the structure and dynamics of molecular and bulk-matter systems, in terms of the interactions of atoms and molecules. The subject matter covers vast territory, including: Explaining the behavior of polymers, fluids and solids, self-assembly of complex systems. Dynamics of simple and complex systems. Study of biophysical systems: enzyme catalysis, protein structure and dynamics, molecular motors, energy transduction, packing of DNA. Properties of nanoscale systems. Molecular collisions and scattering theory, coherent quantum processes, non-linear chemical dynamics, chemical processes at surfaces. The quantum structure of molecules, photochemistry, heterogeneous kinetics and reaction dynamics. Interactions of light and matter, control of chemical processes, new laser technologies

14. Why study chemical physics? Because it is fun!(No, really!) Examples: Model pattern formation in heterogeneous kinetics:

15. Why study chemical physics? Because it is fun!(No, really!) Examples: Use: Understanding chemical waves in cardiac tissue.

16. Why study chemical physics? Because it is fun!(No, really!) Examples: Chemistry of molecular recognition in enzymes.

17. Why study chemical physics? Because it is fun!(No, really!) Examples: Molecular dynamics of membranes (bilayers).

18. Why study chemical physics? Because it is fun!(No, really!) Examples: Building new laser systems.

19. Possible career options: 1. Academia. 2. Government research labs. 3. Industrial research labs. Photonics & laser industry Pure research Drug design in pharmaceutical industry 3. Scientific software developer. Why study chemical physics?

20. What comprises the program? It includes key courses in physical chemistry and certain areas of physics (including electromagnetism and classical mechanics) and allows students to take additional courses in either physics or chemistry depending on their primary interest. Who is suited for the chemical physics program? The Chemical Physics Program is appropriate for students whose interests lie in the interdisciplinary area between chemistry and physics. Students of the program typically pursue graduate degrees in chemical physics or certain areas of physics. Consult: Professor S. Whittington, Department of Chemistry

21. Enrolment in this program requires completion of four courses; no minimum GPA required. Specialist Program: 14 full courses or their equivalent, including at least 1.5 400-series courses. First Year: Intro. Chem ( CHM 151Y or CHM 138H +139H ) Calculus (MAT 137Y/157Y) Intro. Physics. (PHY 131H, 132H) or (PHY 151H, 152H) Chemical Physics Program: then

22. Chemical Physics: Course Requirements Higher Years: Introduction to Physical Chemistry (CHM 225) Linear Algebra (MAT223 or 240) Calculus II (MAT 235 or 237) Intro. to Ordinary Differential Equations (MAT 244) Electricity and Magnetism (PHY 250) Oscillations and Waves (PHY 2544) Complex Variables (MAT 334) Classical Mechanics (PHY 354) Electromagnetic Theory (PHY 350) Differential Equations (APM 346) Application of Quantum Mechanics (CHM423) Two full course equivalents from Intro. Anal. Chem. (CHM 217H), Intro. Org. Chem. (CHM238), Org. Chem. II (CHM 247/249), Environmental Chem. (CHM310), Instrumental Methods (CHM 317), Intermed. Inorg. Chem. (CHM 338), Org. Reaction Mech. (CHM 348), Atmospheric Chem. (CHM415). Further 400-series half-courses in CHM/PHY to make a total of 14 full courses

23. Environmental Chemistry What is it? Study of chemical changes in the environment arising from humankind’s activities Issues? Air pollution, climate change, organic pollutants, soil contamination, water quality How? Analysis of contaminant levels (analytical) Kinetics and mechanism studies (physical, organic) With whom?Toxicologists, atmospheric scientists, oceanographers, geologists, ecologists, statisticians, epidemiologists, … Where? In the lab Everywhere else – e.g. the Arctic, Lake Ontario, Environment Canada field stations, … Afterwards? Academics, government labs, environmental consulting, emerging technologies for energy, public advocacy, public policy, education

24. Environmental Chemistry at UofT - Focus on the development of a strong chemistry background - Take specialist degrees in either Chemistry or Environmental Chemistry - Second year courses: CHM217H – Analytical Chemistry CHM225Y/(220H, 221H) – Physical Chemistry CHM238Y – Inorganic Chemistry CHM249H – Organic Chemistry ENV235Y – Physics and Chemistry of the Earth - In later years: CHM310H – Environmental Chemistry CHM410H – Analytical Environmental Chemistry CHM415H – Atmospheric Chemistry plus a number of other CHM and ENV courses - Get involved in research at St. George: Jon Abbatt (studies of atmospheric particulates), Jamie Donaldson (atmospheric physical chemistry), Scott Mabury (fate of organic pollutants), Jennifer Murphy (field studies of air pollutants)

25. Materials science is the study of the structure, properties, and applications of all types of materials including metals, ceramics, glasses and polymers. Examples of materials with advanced properties: amorphous metals liquid crystals semiconductors nanostructured materials photonic crystals high critical temperature superconductors biomaterials high strength polymers composite materials polymers for tissue engineering materials for drug delivery Materials Science A Collaborative Program between the Faculty of Arts & Science and the Faculty of Applied Science & Engineering

26. Materials science is an interdisciplinary program drawing on the basic sciences of chemistry, physics, polymers, metallurgy and ceramics. The tools of investigation of material structure include electron microscopy x-ray diffraction Auger emission spectroscopy x-ray photoelectron spectroscopy FT-IR spectroscopy Transmission and Scanning Electron Microscopy Confocal Fluorescent Microscopy Materials Science Interdisciplinary Program

27. Coordinators: Professor Eugenia Kumacheva, Department of Chemistry Lash Miller Building, Room 627 Professor Glenn Hibbard, Department of Metallurgy and Materials Science Wallberg Building, Room 140 Enrolment in this program requires completion of four courses no minimum GPA required. Materials Science Program Course requirements

28. Materials Science Course requirements Specialist program: 14 full courses or their equivalent, including at least one 400-series course Students follow one of two streams: Materials Chemistry or Materials Science and Engineering First Year: BIO(120H, 130H), CHM 151Y/(138H, 139H); MAT 135Y/137Y; PHY (131H, 132H)/(151H, 152H) Second Year: MSE 101H; CHM 225Y/(220H, 221H), 238Y, 247H/249H; MSE219H, 235H Third and Fourth Years: 1.CHM 325H, 327H, 338H, 343H/348H, 426H, 434H 2.At least two of the following: MSE 316H, 318H, (342H, 343H), 351H 3.At least two of the following: MSE 430H, 440H, 459H, 461H, 550H Materials Chemistry Stream: CHM 499Y: Introduction to Chemistry Research Materials Science and Engineering Stream: MSE 498Y; Design & Research project

29. Synthetic and Catalytic Chemistry Specialist Program Broad coverage in core areas of chemistry in 1st and 2nd Years plus introductory courses in mathematics, physics and biochemistry. 3rd and 4th Year course requirements focussed on the areas of synthesis and catalysis in organic and inorganic chemistry. Suitable for professional work in chemistry and for entry into graduate school.

30. Synthetic and Catalytic Chemistry Specialist Program Catalysis is revolutionizing the science, technology and art of chemical synthesis. Modern synthetic methods allow for the formation of many classes of molecules, in a manner that quite simply would not have been possible twenty, or even ten, years ago. For example, newly approved pharmaceuticals are not only being increasingly synthesized in bulk using catalytic reactions, but their discovery is often facilitated using catalysis at the earliest stages of the research and development programs. Moreover, there is an increasing need for the development of new methods and catalysts that can be applied toward more efficient, cheaper and environmentally friendly syntheses than are possible with existing technologies. These advances represent a mere fraction of the possibilities for innovation and discovery in this field that will surely emerge in the future.

31. Synthetic and Catalytic Chemistry Specialist Program In the first and second years the program requirements are the same as for the chemistry specialist program. This specialist program requires completion of 14.0 Full Course Equivalents, including the following required courses. First Year: CHM151Y (strongly recommended) or CHM138H + 139H MAT135Yor MAT137Y PHY (131H1, 132H1) or (151H1, 152H1) Inorganic - CHM238Y Organic - CHM249H (strongly recommended) or CHM247H Analytical - CHM217H Physical - CHM225Y or (CHM220H min grade B & CHM221H) Calculus II - MAT235Y or MAT237Y Biochemistry - BCH210H Second Year:

32. Synthetic and Catalytic Chemistry Specialist Program CHM 432H Organometallic Chemistry CHM 440H Synthesis of Modern Pharmaceutical Agents CHM 441H Spectroscopic Analysis in Organic Chemistry CHM 443H Physical Organic Chemistry 3rd Year: 4th Year: CHM 317H Introduction to Instrumental Analysis CHM 338H Intermediate Inorganic Chemistry CHM 342H Modern Organic Synthesis CHM 343H Organic Synthesis Techniques CHM 347H Organic Chemistry of Biological Compounds CHM 348H Organic Reaction Mechanisms Research Experience: CHM 398H Independent Experiential Project or CHM 499Y Introduction to Chemistry Research

33. Synthetic and Catalytic Chemistry Specialist Program PLUS a further 0.5 or 1.0 Credits from the following 3rd & 4th Year Chemistry Courses to make a total of 14.0 Credits: CHM 325H Introduction to Inorganic and Polymer Materials Chemistry CHM 328H Modern Physical Chemistry CHM 379H Biomolecular Chemistry CHM 416H Separation Science CHM421H Chemical Kinetics and Dynamics CHM 434H Advanced Materials Chemistry CHM 437H Bio-inorganic Chemistry CHM 447H Bio-organic Chemistry CHM 479H Biological Chemistry Consult: Professor Rob Batey, Dept. of Chemistry

34. Synthetic and Catalytic Chemistry Specialist Program This program is quite distinct from the other Chemistry Specialist programs. The required courses provide students with a laboratory intensive learning experience, and include a requirement for upper level independent research. Such synthetically trained students are in high demand in the pharmaceutical, biotechnology, crop protection, materials and related discovery intensive sectors. For example, the training obtained in the area of synthesis and catalysis is considered to be the ideal preparation for entry into medicinal and process chemistry departments in pharma/biotech companies. Career opportunities

35. Major / Minor Programs The major and minor programs in Chemistry are intended for those students who wish to take some chemistry courses, but who do not wish to follow one of the specialist programs. The major program requires completion of 8 full courses or their equivalent, while the minor requires only 4 full courses. For more information, contact the Undergraduate Office, Lash Miller Rm 151.

36. Chemistry Major Course requirements First Year: CHM 151Y/(138H, 139H; MAT 135Y/137Y Second Year: At least two of CHM 217H, 220H/225Y, 238Y, 247H/249H (CHM249H strongly recommended) Third Year: At least two of CHM 317H, 327H, 338H, 343H, 348H), 379H Fourth Year:Further 200/300/400-level CHM courses to make a total of seven CHM full course equivalents (CHM 299Y excluded) Eight full courses or their equivalent, including at least one CHM half-course equivalent at the 400 level.

37. Chemistry Minor First Year: CHM 151Y/(138H, 139H) Second Year: At least one of CHM 217H, 220H/225Y, 238Y, 247H/249H (CHM249H strongly recommended) Third Year: At least one of CHM 317H, 327H, 338H, 343H, 348H, 379H Fourth Year:Further 200/300/400-level CHM courses to make a total of four CHM full course equivalents (CHM 299Y excluded) Four full courses or their equivalent, including at least one CHM full-course equivalent at the 300+ level.

38. Environmental Chemistry Minor 1.CHM 151Y/(138H, 139H) 2.One full course equivalent from CHM 217H, (220H, 221H)/225Y, 238Y, 247H/249H 3.ENV 235Y 4.Any two of CHM310H, 317H, 410H, 415H Four full courses or their equivalent, including at least one full- course equivalent at the 300+ level.

39. Nanoscience Minor This physical science-based minor program represents a unique opportunity to study chemistry and physics in a different cultural environment. Students take core subjects at the first-year level in Toronto and spend the spring semester of their second or third year at the National University of Singapore, where they are enrolled in lecture courses and undertake a faculty-supervised research project. Four full courses or their equivalent, including at least one full-course equivalent at the 300+ level. 1.CHM 151Y/139H, PHY (131H,132H)/(151H,152H) 2.NUS 227H, 228H, 328H, 398H* 3.Further CHM courses to make a total of four CHM full course equivalents *NUS courses must be taken at the National University of Singapore during either the spring semester of second year studies or the spring semester of third year studies. Consult: Dr. Andy Dicks, Dept. of Chemistry

41. B.Sc. in Chemistry leads to numerous career paths Career Opportunities

42. Undergraduate Office At some time in your undergraduate career you will certainly need some advice from someone who is knowledgeable about your major field of interest. The staff at the Department will be pleased to discuss your program with you and to give advice on course selection. If you have questions, come to or contact the Undergraduate Office: Lash Miller Building, Room 151 416-978-6033 undergrd@chem.utoronto.ca