1. NIH Funding Opportunities for Economists C-FARE Session AAEA Annual Meeting Montreal July 26, 2003 Rachel A. Nugent, Ph.D. Fogarty International Center National Institutes of Health

2. Overview of Presentation Opening the black box: what is NIH? Opening the black box: what is NIH? Why consider applying for funding at NIH? Why consider applying for funding at NIH? What to do before applying What to do before applying After you apply After you apply Opportunities for economists at NIH Opportunities for economists at NIH Contact me with questions Contact me with questions

4. Why apply for funding at NIH?  New emphasis on social and behavioral research  Increase in inter-disciplinary research  $2.5 billion in behavioral and social science research throughout NIH

5. How NIH grant funding works 80% investigator-initiated proposals 80% investigator-initiated proposals  Three deadlines per year on a revolving basis  Fixed receipt dates: Feb 1, June 1, Oct 1 20% respond to solicitations: PAs and RFAs 20% respond to solicitations: PAs and RFAs Referred to appropriate IC and peer reviewed Referred to appropriate IC and peer reviewed IC determines funding line IC determines funding line

6. Main types of research grants for investigators: R01 - Research Project Grant R01 - Research Project Grant R03 - Small Grant R03 - Small Grant R21 – Planning Grant R21 – Planning Grant K01 – Research Career Development Award K01 – Research Career Development Award

7. Special funding initiatives: RFA: Request for Applications RFA: Request for Applications PA: Program Announcement PA: Program Announcement How NIH asks researchers to consider certain topics or areas How NIH asks researchers to consider certain topics or areas Also how NIH notifies researchers that funding mechanisms (e.g., R03s) are available Also how NIH notifies researchers that funding mechanisms (e.g., R03s) are available

8. RFA versus PA: RFAPA Funds set aside for projects? Yes Usually not Special application deadlines? Yes Usually not How long active? Until deadline 3 years Special review panel? Often Usually not

9. Is it worth the effort? True, NIH is very competitive True, NIH is very competitive Grant applications are demanding Grant applications are demanding Most senior NIH researchers failed initially, but eventually succeeded Most senior NIH researchers failed initially, but eventually succeeded But, you control the science But, you control the science NIH support is generous and prestigious NIH support is generous and prestigious

10. Things to do before applying Identify target IC and relevant program staff Identify target IC and relevant program staff Get advice from program staff about research plan and funding mechanisms Get advice from program staff about research plan and funding mechanisms Review the website for: Review the website for:  Research recently funded  Current RFAs and PAs  Information for applicants

11. CRISP Computer Retrieval of Information on Scientific Projects Database of federally-funded biomedical research  National Institutes of Health (NIH),  Substance Abuse and Mental Health Services (SAMHSA),  Health Resources and Services Administration (HRSA),  Food and Drug Administration (FDA),  Centers for Disease Control and Prevention (CDCP),  Agency for Health Care Research and Quality (AHRQ),  Office of Assistant Secretary of Health (OASH).

12. Use CRISP to:  Search for scientific concepts, emerging trends and techniques  Search for funded grant abstracts  Find NIH institutes interested in your area  Find the NIH study section that reviews applications in your research area

13. http//:www.nih.gov NIH HOMEPAGENIH HOMEPAGE

14. Watch for the GUIDE in a later slide GRANTSPAGEGRANTSPAGE

15. http://crisp.cit.nih.gov CRISPHOME PAGECRISPHOME PAGE

16. CRISPSEARCHCRISPSEARCH

17. CRISPRESULTSCRISPRESULTS

18. CRISPABSTRACTCRISPABSTRACT

19. http://grants.nih.gov/grants/guide/index.htmlhttp://grants.nih.gov/grants/guide/index.html

20. Do more digging Find NIH grantees and ask them for: Find NIH grantees and ask them for:  Successful applications  Successful summary statements  Unsuccessful summary statements  “Summary statement” is the written critique from the peer review, called “pink sheet”

21. Additional preparation (cont.) Work with a researcher who has been through the NIH process Work with a researcher who has been through the NIH process Choose the right topic Choose the right topic  Something you know  Something you are recognized for  Don’t go beyond what you can do

22. Study the “study section” Look up the rosters of recent study sections: Look up the rosters of recent study sections:  Center for Scientific Review www.csr.nih.gov/Committees/rosterindex.asp  IC-specific Divisions of Scientific Review Ascertain what study section will review your proposal Ascertain what study section will review your proposal Talk to the program officer about the study section if you have any concerns Talk to the program officer about the study section if you have any concerns

23. NIH Review System What do the reviewers want to determine? What do the reviewers want to determine?  SCIENTIFIC CREDIBILITY What does the IC want to determine? What does the IC want to determine?  WILL THE WORK HAVE IMPACT AND BE SUCCESSFUL IF FUNDED Who reviews? Who reviews?  Center for Scientific Review  Institutes’ own review panels  Special Emphasis Panel

24. How Does the Application Flow Through the System? Comes into CSR Comes into CSR>65,000 applications per year >500,000,000 pieces of paper pieces of paper

25. Panel-Make Up Scientific Review Administrator (SRA) Scientific Review Administrator (SRA) Chairperson Chairperson Panel Members Panel Members First, second and third reviewers First, second and third reviewers

26. Review, funding decision, and after Wait for your priority score and summary statement Wait for your priority score and summary statement Contact the program officer with questions Contact the program officer with questions If unsuccessful, consider an appeal or reapplication If unsuccessful, consider an appeal or reapplication If successful, fulfill ALL your promises, stay in touch with your program officer If successful, fulfill ALL your promises, stay in touch with your program officer

27. Human Subject Concerns http://ohrp.osophs.dhhs.gov/index.html http://ohrp.osophs.dhhs.gov/index.html http://ohrp.osophs.dhhs.gov/index.html Federal Wide Assurance (FWA) Federal Wide Assurance (FWA) The Federal Policy (Common Rule) for the protection of human subjects at Section 103(a) requires that each institution "engaged" in Federally-supported human subject research file an "Assurance" of protection for human subjects. The requirement to file an Assurance includes both "awardee" and collaborating "performance site" institutions. The Federal Policy (Common Rule) for the protection of human subjects at Section 103(a) requires that each institution "engaged" in Federally-supported human subject research file an "Assurance" of protection for human subjects. The requirement to file an Assurance includes both "awardee" and collaborating "performance site" institutions.

28. What’s inside the black box for economists? National Institute for Child Health and Development National Institute for Child Health and Development National Institute on Aging National Institute on Aging Office of Behavioral and Social Science Research/OD Office of Behavioral and Social Science Research/OD Fogarty International Center Fogarty International Center National Institute on Drug Abuse National Institute on Drug Abuse National Institute on Alcoholism and Alcohol Abuse National Institute on Alcoholism and Alcohol Abuse National Institute of Mental Health National Institute of Mental Health

29. NICHD: Demographic and Behavioral Sciences Branch Economist: Jeff Evans, Ph.D. Economist: Jeff Evans, Ph.D.  Economic Demography  Intergenerational Transactions https://www.nichd.nih.gov/about/cpr/dbs.htm http://www.nichd.nih.gov/about/cpr/dbs/htm#staff

30. NICHD (cont.) Demographer: Rebecca Clark, Ph.D. Demographer: Rebecca Clark, Ph.D.  Population and environment  Immigration  Population movement  Demographic Methods http://grants.nih.gov/grants/guide/pa-files/PA-98-098.html http://grants.nih.gov/grants/guide/pa-files/PA-95-036.html

31. NIA: Behavioral and Social Research Associate Director: Richard Suzman, Ph.D. Associate Director: Richard Suzman, Ph.D.  Individual Behavioral Processes  Population and Social Processes  Demography and Epidemiology  Health and Retirement  Health and Social Institutions http://www.nia.nih.gov/research/extramural/behavior/programs.htm

32. OBSSR: Behavioral and Social Science Research Chief: Virginia Cain, Ph.D. Chief: Virginia Cain, Ph.D.  Methodology and Measurement in Social Science ()  Methodology and Measurement in Social Science ( PA-02-072 ) http://grants1.nih.gov/grants/guide/pa-files/PA-02-072.html  Social and Cultural Dimensions of Health ( PA-02-043) http://grants.nih.gov/grants/guide/pa-files/PA-02-043.html

33. Fogarty International Center, NIH Mission: Promote and support scientific research and training internationally to reduce disparities in global health. “Science for Global Health”

34. Fogarty International Center International Studies in Health and Economic Development (ISHED) International Studies in Health and Economic Development (ISHED) http://grants.nih.gov/grants/guide/rfa-files/RFA-TW-01-001.html Health, environment and economic development (HEED) Health, environment and economic development (HEED) http://grants2.nih.gov/grants/guide/rfa-files/RFA-TW-03-005.html International Research Scientist Development Award (IRSDA) K01 International Research Scientist Development Award (IRSDA) K01 http://grants.nih.gov/grants/guide/pa-files/PAR-02-041.htm

35. International Studies in Health and Economic Development Purpose: R01 research grants to examine and establish the scientific basis for linkages between health and economics; including microeconomic behavior, health systems analysis, health financing, macroeconomic impacts and measures Purpose: R01 research grants to examine and establish the scientific basis for linkages between health and economics; including microeconomic behavior, health systems analysis, health financing, macroeconomic impacts and measures

36. International Studies in Health and Economic Development 11 research grants in FY 2001-2005, 5 full awards and 6 development awards 11 research grants in FY 2001-2005, 5 full awards and 6 development awards Examining links between health and economic outcomes Examining links between health and economic outcomes 4 of the full awards examine impacts of nutrition on cognitive and economic outcomes 4 of the full awards examine impacts of nutrition on cognitive and economic outcomes

37. ISHED (cont.) 3 awards examining impact of HIV/AIDS on economic outcomes 3 awards examining impact of HIV/AIDS on economic outcomes Other studies looking at impacts of iron supplementation, micronutrient deficiency and education intervention on multiple physical and economic pathways Other studies looking at impacts of iron supplementation, micronutrient deficiency and education intervention on multiple physical and economic pathways

38. Health, Environment and Economic Development (HEED) Objective: support interdisciplinary, international research collaborations on the linkages among health, environment, and development in developing countries

39. 3 million children die from environmentally related causes each year.

40. Over 1 million people die each year from work-related diseases and injuries. Over 800 million people in the world are food insecure.

41. 80-90% of diahhreal cases are related to environmental degradation.

42. Children in mega-cities receive 2-8 times WHO guidelines for air pollutants. By 2006, more than 50% of the world’s population will live in urban areas.

43. 2-3.5 billion people in developing countries rely on traditional fuels for cooking and heating.

44. Inappropriate livestock-rearing practices lead to zoonotic disease and antibiotic resistance.

45. Developmental grants in 2003 Developmental grants in 2003 Full research grants in 2005-6 Full research grants in 2005-6 Strong research capacity building Strong research capacity building Policy relevance and dissemination plans Policy relevance and dissemination plans Evaluation of impacts Evaluation of impacts Program Highlights Health, Environment and Economic Development (HEED)

46.   Health & Environmental Impacts of a Major Pipeline Project in Chad   Ecological Approach to Malaria Control in Brazil   Reducing SO2 Emissions in Taiyuan, China   Air Quality, Respiratory Health and Industrial Zoning in Delhi HEED Topics Health, Environment and Economic Development (HEED)

47.   Factors Associated with the Use of Pesticides in southern Africa   Water Privatization Policies and Health in Chile   Impact of Leishmaniasis on HEED in Tunisia HEED Topics Health, Environment and Economic Development (HEED)

48. Career Development Award – K01 Open to U.S. post-docs and junior faculty Open to U.S. post-docs and junior faculty Four years of salary support to develop global health research career Four years of salary support to develop global health research career Develop a mentored training and research plan Develop a mentored training and research plan Exs: Evaluation of Progresa program, economic impact of AIDS funerals, transmission of SFV through bushmeat Exs: Evaluation of Progresa program, economic impact of AIDS funerals, transmission of SFV through bushmeat

49. g r o w i n g Issue: Obesity NIH Task Force formed in April 2003 to design obesity research agenda NIH Task Force formed in April 2003 to design obesity research agenda Issue will receive substantial funding Issue will receive substantial funding Trans-NIH and cross-disciplinary Trans-NIH and cross-disciplinary

50. Building a Framework for Organizing and Coordinating Obesity Research Activities Identification of genetic, behavioral and environmental factors causing obesity Identification of genetic, behavioral and environmental factors causing obesity Understanding pathogenesis of obesity and its comorbidities Understanding pathogenesis of obesity and its comorbidities Prevention and treatment of obesity Prevention and treatment of obesity Policy, health services, economics, translation to practice Policy, health services, economics, translation to practice Enabling technologies Enabling technologies Development of multi-disciplinary research teams Development of multi-disciplinary research teams

51. NIH Obesity Research Outcome Goals (Draft 6/03) Use knowledge of regulation of energy storage and food intake to develop new therapeutic modalities (including drugs, surgery, and other technologies) to complement lifestyle interventions Use knowledge of mechanisms whereby obesity increases risk for co-morbidities to develop potential therapeutic approaches for ameliorating these conditions independent of weight loss Evaluate the effectiveness and assure translation of strategies to maintain healthy weight in children and adults through behavior (activity, diet) change which can be applied in a home, school, or workplace environment

52. Some Sources of Information on NIH Grant Writing http://www.niaid.nih.gov/ncn/grants/default.htmhttp://www.nigms.nih.gov/funding/tips.htmlhttp://www.niddk.nih.gov/fund/grants_process/grantwriting.htmhttp://deainfo.nci.nih.gov/EXTRA/EXTDOCS/gntapp.htmhttp://www.drugabuse.gov/Funding/Grantapps.htmlhttp://www.nigms.nih.gov/funding/tips.htmlhttp://grants.nih.gov/grants/guide/notice-files/not97-010.html

53. Feel free to contact:  Program officer: Dr. Rachel Nugent  nugentra@mail.nih.gov  301-496-8733  For further information: http://www.nih.gov/fic/programs/econ.html