1. #hfeaconference2014 26 February 2014 Anthony Rutherford Multiple Births Stakeholder Group member 100% committed to 10% Still One at a Time

2. Where it all started…

3. Year by year… ‘Year’ 1: Jan 2009 – end March 2010: 24% Year 2: April 2010 – end March 2011: 20% ‘Year’ 3: April 2011- end September 2012: 15% Year 4: October 2012 – end September 2013: 10%

4. Multiple Births Stakeholder Group

5. Multiple Births Stakeholder Group continued Good progress, but we’re not quite there yet 100% committed to the policy Work together to share best practice Continue to educate patients, public & commissioners HFEA continues to take regulatory action with non-compliant clinics

6. Workshop overview Overview of national trends and sector progress Hannah Verdin, Interim Head of Policy & Communications, HFEA Key factors of a successful strategy Andrew Riddle, Medical Director & Person Responsible, Nuffield Health Woking Hospital (Surrey IVF) Discussion Have we got patients on board? Valerie Peddie, Honorary Research Fellow, Aberdeen Maternity Hospital Discussion

7. #hfeaconference2014 26 February 2014 Hannah Verdin Interim Head of Policy and Communications, HFEA Overview of national trends & sector progress

8. Overview of national trends

9. Pregnancy rates eSET vs DET: Year 4

10. Preg. rates blastocyst eSET vs. DET: Year 4

11. Focus on blastocyst transfer

12. Multiple birth rate continues to decrease Overall pregnancy and live birth rates remain steady eSET rate & blastocyst rate continue to rapidly increase Multiple pregnancy rates following DET slightly reduced, although still high: 23-40% depending on age & stage of embryo Any cause for concern? Slight increase in proportion of double blastocyst transfers Moving on to individual centre performance... Key trends

13. Year 3 centre performance: funnel plot Multiple live birth rate by live birth, for all IVF, ICSI and FET cycles For period: Apr 2011 – Sep 2012 (as of 09/01/14) at 15% Number of births

14. Year 4 centre performance: funnel plot Multiple live birth rate by live birth, for all IVF, ICSI and FET cycles For period: Oct 2012 – Sep 2013 (as of 09/01/14) at 10% Number of births

15. Next steps Continue to convene Multiple Births Stakeholder Group: sharing best practice Continue to update One at a Time website: educating patients, public & commissioners Relevant wider work: CAFC and website review, dataset review, corporate strategy, communications & information for commissioners Continue to work with you and monitor performance

16. Thank you. #hfeaconference2014