1. Improving Clinical Research across the UK – Who, Why, How? Matthew Hallsworth, Communications Programme Manager Marianne Miles, Patient and Public Involvement Lead Wednesday 6th September 2006

2. Who? - UKCRC A partnership of organisations working together to re-engineer the environment for clinical research in the UK –A new way of working –A forum for leadership –An opportunity

4. Why?

5. How? NHS Infrastructure (Exp Med, Networks, IT systems) Research Workforce Regulatory and Governance environment Coordinating Research Funding NHS Incentives

6. Public Awareness and Patient & Public Involvement are key themes Awareness –Generic information resources –Educational resources on clinical research Involvement –‘The Exchange’ –The evidence base

7. Who? - UKCRN Aim to provide a world-class health service infra- structure to support clinical research To make the NHS the best place in the world to do clinical research A managed set of Clinical Research Networks to facilitate studies (including prevention, diagnosis, treatment, care)

8. Targeted research funding, initially: Cancer Dementias and Neurodegenerative Diseases Diabetes Medicines for Children Mental Health Stroke Primary Care UKCRN to cover all aspects of disease and clinical need: ‘Comprehensive UKCRN’ – April 2007

9. How - key UKCRN areas: Trials and Trials Units Support Regulatory & Governance Primary Care Industry Experimental Medicine Patient and Public Involvement (PPI) Information Systems Training and Education

10. Why PPI? To positively influence/increase public awareness around clinical research To enhance overall quality and relevance of UK clinical research

11. How? Experience: cancer, and mental health E.g. - identifying important and relevant research - asking the right questions in the best way - helping researchers to design their projects - helping to develop accessible information - joining a research advisory group - helping to interpret research results - helping to promote good research Support for ALL involved Opportunity: coordination, ↑ profile, improved clinical studies leading to patient benefits

12. Matthew HallsworthMarianne Miles Communications Programme Manager Patient and Public Involvement Lead UK Clinical Research Collaboration (UKCRC) UK Clinical Research Network (UKCRN) 20 Park Crescent UKCRN Coordinating Centre LondonArthington House, Cookridge Hospital, W1B 1ALHospital Lane, Leeds LS16 6QB T: +44(0)20 7670 5389T: +44(0)113 392 4398 Stephenson House, 158-160 North Gower Street, 4th Floor, London NW1 2ND T: +44(0)20 7670 4871 Email: matthew.hallsworth@ukcrc.org Email: m.miles@ukcrn.org.uk Website: www.ukcrc.org Website: www.ukcrn.org.uk