1. 2003-2004 Antibiotics Review 10 August 2015 6:39 AM

2. Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

3. Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation

4. Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking

5. Amphotericin B Antifungal Polyene antibiotic Binds to ergosterol and alters permeability Systemic

6. Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

7. Aztreonam New  lactam antibiotic Monobactam

8. Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a  lactam, Inhibits dephosphorylation of bactoprenol

9. Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation

10. Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

11. Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation Oral

12. Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

13. Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4 th generation CSF penetration

14. Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

15. Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation

16. Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation

17. Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

18. Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation CSF penetration

19. Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

20. Cephalosporins Antibiotics  lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

21. Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

22. Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation

23. Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

24. Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

25. Clavulanic acid  -lactamase inhibitor Combined with antibacterials

26. Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections

27. Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

28. Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide

29. Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy

30. Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

31. Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

32. Ethambutol Antibiotic Major drug for tuberculosis

33. Ethionamide Antibiotic Secondary drug for tuberculosis

34. Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase

35. Gentamicin Aminoglycoside antibiotic bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

36. Imipenem/Cilastatin New  lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem

37. Isoniazid Antibiotic Inhibits biosynthesis of mycolic acids Major drug for tuberculosis

38. Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit

39. Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome

40. Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

41. Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

42. Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

43. Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

44. Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical

45. Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

46. Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

47. Nystatin Antifungal Polyene antibiotic Binds to ergosterol & alters permeability Topical

48. Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

49. Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

50. Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug

51. Penicillins  lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

52. Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking

53. Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking

54. Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

55. Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal

56. Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking

57. Pyrazinamide Antibiotic Major drug for tuberculosis

58. Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB

59. Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

60. Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome

61. Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

62. Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

63. Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor

64. Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

65. Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

66. Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase

67. Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

68. Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

69. Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

70. Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase

71. Trimetrexate Antibiotic Folic acid antagonist Treatment for Pneumocystis carinii

72. Vancomycin Antibiotic Inhibits cell wall synthesis Not a  lactam