26. If current trends continue, 250 million children alive today will die from tobacco-related disease. In China alone, about 50 million youth will eventually be killed by tobacco.

27. Tobacco deaths WHO World Health Report 1999.

29. 4 Stages of the Tobacco Epidemic Sub- Saharan Africa China Japan Southeast Asia Latin America North Africa Eastern Europe Southern Europe Western Europe, UK USA Canada Australia Countries in each stage Adapted from: Lopez AD, Collishaw NE, Piha T. A descriptive model of the cigarette epidemic in developed countries. Tobacco Control, 1994, 3:242-247. STAGE 1 STAGE 2 STAGE 3 STAGE 4

30. International tobacco control has few resources Less than $100 million per year is spent on international tobacco control, excluding the US, Canada and Australia. This year, nearly $2 billion will be spent in the US alone.

33. It’s a Small, Small (separate) World Technology and Economics

34. Americans On Line

35. Rapid Changes in Physician Computing Those physicians saying:

36. Genetics Nanotechnology Smart Drugs Promising Areas of Research

37. Comparative Health Care Expenditures $ per capita

38. Female and Male Life Expectancy at Birth

39. What is and What Could be Future Opportunities

40. “How cancer develops is no longer a mystery.” Robert A. Weinberg Scientific American, September 1996 Understanding Cancer

41. Today's Trend in Gaps and Bottlenecks What is Knowable Narrowing Widening Known What could be

42. Gaps and Bottlenecks Science Impact Knowable vs. Known "Doable" "Done" Implementation Discovery Lives Saved Gap between what is known and what is knowable Gap between what is vs. what could be

43. Access Prevention & Prompt Quality Patient & family Protection State-of-the-Art of Life preferences at Care and Follow-up end of life. Prevention Saving Lives Reducing Suffering The Gap Optimum

44. Fight, Fight Talk, Talk Fight, Fight Talk, Talk Three approaches

48. Approach and Framework of the Report… Discovery, Research and Training Translation of Science into New Modalities Access to Quality Care Delivery of Quality Cancer Prevention & Care

50. Never doubt that a small group of people can change the world. Indeed, it’s the only thing that ever has. Margaret Mead

52. Review Questions (developed by Supercourse Team) Describe “how the world dies today”, using examples of both chronic and infectious disease List three cancers that have been controlled in Western world by controlling infectious agent that causes them. Describe cancers that have been on the rise due to the adoption of western lifestyle. What is the leading cause of preventable disease and death?