1. By Matthew Morgan, Andrew Lomanto, Taylor Stauffer http://www.kiwifamilies.co.nz/T opics/Support+Groups/Illness/ Cystic+Fibrosis.html

2. What is Cystic Fibrosis -A hereditary disorder -Makes glands secrete a sticky mucus which clods the pancreas, liver, and intestines. -Infection of the lungs http://www.nlm.nih.gov/medlineplus/ency/imagepages/18135.htm

3. Cystic Fibrosis Inheritance Both parents can carry the gene Occurs right after birth Child has 25% chance of getting Cystic Fibrosis if both parents are heterozygous carriers and 50% of being a carrier Abnormal recessive gene Both parents need to be carriers in order for the off spring to inherit Cystic Fibrosis

4. Cystic Fibrosis Inheritance Punnet Square http://www.csupomona.edu/~biology/bio110/inherit/genes.html

5. Cystic Fibrosis Frequency 1/25 of all Caucasians carry this disease http://www.greatstrides.com.au/images/ nebulisertreatment.jpg http://breathe4tomorrow.org/wp- content/uploads/2008/12/alexus.jpg

6. Symptoms and Effects - Very salty skin - Frequent coughing - Wheezing - Impaired growth (due to lack of nutrition) - Greasy feces SymptomsEffects -Because of sticky mucus, the pancreas is clogged, which impairs digestive enzyme flow to intestines, which minimizes the patient, potential to digest food and harvest nutrients -Sticky mucus also creates a layer around the lungs makes it harder for patient to breath, especially during cardio activates -Average life expectancy of persons with Cystic Fibrosis: about 30 years http://www.exposay.com/wee man-the-world-premiere-of- jackass-number- two/p/4630/65/

7. How is it Diagnosed? Usually discovered in early childhood Simple procedure, where the patient is tested for excessive levels of sodium chloride in their sweat http://www.baynews9.com/article/news/2011/ january/192524/New-hope-for-people-living- with-cystic-fibrosis

8. How is this Disease Treated? It is possible to extract the pancreas, to overcome the lack of digestive enzyme flow Daily back slapping is in order, because it helps break up the mucus. Gene Therapy- It is possible to inject a normal, healthier gene into the patient. This therapy has had high hopes from scientists, but has shown no positive results yet. Currently, there are a few known antibiotics that have proven to increase one’s life expectancy

9. Is There a Cure? There is no known cure, but scientists everywhere are striving to produce one for this disease. There is a foundation for this disease, which raises money for aid to the current patients, and for finding a cure in the near future

10. SMaRT Therapy A type of gene therapy, which takes advantage of the need to remove introns. This makes a functional mrna, so genes will continue to reduce possibility of the patient’s child getting the disease

11. Works Consulted “About Cystic Fibrosis.” Cystic Fibrosis Foundation. Cystic Fibrosis Foundation, n.d. Web. 28 Jan. 2011.. “Cystic Fibrosis.” Encyclopedia of Genetics. Ed. Don P. Dawson. Vol. 1. Pasadena, CA: Salem Press Inc., 2004. 195-198. Print. “Cystic Fibrosis.” Genetic Science Learning Center. Learn Genetics, 28 Jan. 2011. Web. 28 Jan. 2011.. Jacoby, David R., and Robert M. Youngson. “Cystic Fibrosis.” Encyclopedia of Famliy Health. Ed. Joyce Tavolacci. Vol. 4. Tarrytown, NY: Marshall Cavendish, 2005. 448. Print. “What is Cystic Fibrosis.” TOBI. TOBI, 2011. Web. 28 Jan. 2011..