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Tena Trbojević Mentor: A. Žmegač Horvat

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Presentation on theme: "Tena Trbojević Mentor: A. Žmegač Horvat"— Presentation transcript:

1 Tena Trbojević Mentor: A. Žmegač Horvat
Rheumatoid arthritis Tena Trbojević Mentor: A. Žmegač Horvat

2 Rheumatoid arthritis chronic diesease inflammatory disease
(inflammation of joint lining) autoimmune disease (immune reaction against joint tissues - synovial membrane)

3 Rheumatoid arthritis causes pain, swelling, stiffness, loss of function in the joints generally occurs in a symmetrical pattern may also attack tissue in the skin, lungs, eyes, and blood vessels

4 Rheumatoid arthritis small joints of hands and feet affected first, larger joints later

5 Rheumatoid arthritis begins during the most productive years (30 – 60)
occurs much more frequently in women than in men (w:m=3:1)

6 Rheumatoid arthritis specific agent or agents are not yet known infectious agents, such as viruses and bacteria, may trigger RA in people with an inherited tendency to develop the disease

7 Rheumatoid arthritis synovitis fibrous ankylosis bony ankylosis

8 Rheumatoid arthritis

9 Rheumatoid arthritis - symptoms:
Around the joints warmth redness swelling pain limitations in joint motion General sickness tiredness fever

10 Rheumatoid arthritis can be difficult to diagnose in its early stages
Patient history - questions about the intensity of pain symptoms - frequency of symptoms - what makes the pain better or worse RTG, MRI, arthrography, arthroscopy Blood test (RF, CRP, SE) RF→ Waaler- Rose test 1:32=normal 1:64≤ pathological

11 Rheumatoid arthritis Treatments can: relieve pain reduce swelling
slow down or help prevent joint damage increase ability to function improve sense of well-being

12 Rheumatoid arthritis – treatment options:
exercise medication stress reduction DMARDs (disease-modifying anti-rheumatic drugs): methotrexate, leflunomide, sulfasalazine, cyclosporine corticosteroids : cortisone, hydrocortisone, prednisone in some cases - surgery (joint replacement and tendon reconstruction - two types of surgery available to patients with severe joint damage )

13 Rheumatoid arthritis research efforts: focused on developing drugs that can reduce inflammation and slow or stop the disease with few side effects; investigators trying to identify the infectious agents and understand how they work → new therapies scientists are also examining why rheumatoid arthritis often improves during pregnancy

14 Rheumatoid arthritis

15 References:

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