1. Magnetic applications of nanocellulose
Nikorn Laocharoen (465454)
26 Feb 2015
Nanotechnology in Forest Biomaterials

2. What is the magnetic of nanocellulose?
What is magnet?
Material or object that produces a magnetic field by itself
Magnetic field is invisible
Element: Fe, Co, Ni
What is the magnetic of nanocellulose?
Combination of magnetic nanoparticle and nanocellulose
Resulting in improved properties; mechanical strength, more flexible, and
Magnetic, Thermal property
Emulsion, Impregnation
Grafting, Composite etc.
Nano cellulose
Magnetic particle

3. Application Fields Medical/ Biotechnology Tumor/ Cancer Drug Delivery
Nano emulsion
Magnetic hybrid cellulose
aerogels
Magnetic nanopaper
Nano composites
Films for packaging
Rubber
Nanofiber

4. Application in medical treatment
Inhibit growth of tumor cell
Hard core (inner) CoFe2O4
Soft shell (outer) MnFe2O4
Magnetic nanoparticles
Magnetic Fluid Hyperthermia (MFH):
Magnetic nanoparticles are injected into the tumor
Apply the external magnetic field
Magnetic thermal induction by nanoparticles
Tumor regression is observed
Superior to conventional anticancer drug

5. Application in medical/ biotechnology
Drug and Biomolecules delivery:
Engineered nanoparticles
Commercialized level
How to obtain?
Iron oxide Size < 100 nm
Surface functionalization to magnetic
nanoparticles
Directly adsorption of drug onto the surface
Surface coating (Inorganic; silica, gold)
for biocompatibility
Functionalized with DNA carrier
Magnetically triggered release of drugs and
biomolecules

6. Application in Colloid and Interface
compaction
Features:
Tunable and strong mechanical property
Used as templates for making lightweight
porous magnetic aerogels
Then, compact such aerogels to form
magnetic nanopaper
Advantages:
Lightweight
Porous (98%) with high surface area
Flexible
Absorb large amount of water
Apply in microfluidic devices and electronic
actuators

7. Ferrite Rubber Composite
Application in Nano composites
Magnetic self standing films
Advantages:
Anti-counterfeit in security
documents
Magnetic ink
Coating
Micro-patterning
CNC–inorganic (Barium
Ferrite) dispersion and then
removal of water via filtration
(light brown color)
Put in magnet and use magnetic
field viewer to distinguish
Composite material in natural rubber
Advantages:
Low weight (than ceramic)
Resistance to corrosion
Highly flexible
Ease of machining and forming
Ferrite powder
Ferrite Rubber Composite
(FRC)
Composite material in nanofiber
Advantages:
Improved mechanical strength
Strong interaction with water (owing to
The presence of CNC)
Biocompatible (may apply as fluid
Hyperthermia)
Electrospinned PVA fiber
composite with magnetic
CNC-inorganic

8. Conclusion Magnetic application illustrates broad range of utilization
High impact on well-being life of humankind in the future (tumor/cancer therapy)
Many of the magnetic application are still in research and development phase

9. Personal perspective on this topic
Long term investigation from utilizing magnetic nanocellulose in human
Recycling aspects of some composite materials (is it easily recycled
or reused)
Take the advantages of magnetic feature for heavy metal seperation (i.e. water treatment)
Possibility for scale up production (cost of large scale production, market demand)

10. References:
Bonini M., Berti D., Baglioni P., Nanostructures for magnetically triggered release of drugs and biomolecules. Current Opinion in Colloid & Interface Science. 18, p.459–467.
Jordan A., Scholz R., Wust P., FaK hling H., Felix R., Magnetic fuid hyperthermia (MFH): Cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles. Journal of Magnetism and Magnetic Materials. 201, p
Lee J., Jang J., Choi J., Ho Moon S., Noh S., Kim J., Kim J., Kim I., In Park K., Cheon J., Exchange-coupled magnetic nanoparticles for efficient heat induction. Nature Nanotechnology. 6, p
Makleda, M.H., Matsuib T., Tsudab H., Mabuchib H., El-Mansya M.K., Moriib K., Magnetic and dynamic mechanical properties of barium ferrite–natural rubber composites. Journal of Materials Processing Technology. 160, p.229–233.
Olsson R.T., Azizi Samir M.A.S., Salazar-Alvarez G., Belova L., Ström V., Berglund L.A., Ikkala O., Nogue J.and Gedd U.W., Making flexible magnetic aerogels and stiff magnetic nanopaper using cellulose nanofibrils as templates. Nature nanotechnology. 5, p
Ridi F., Bonini M., Baglioni P., Magneto-responsive nanocomposites: Preparation and integration of magnetic nanoparticles into films, capsules, and gels. Advances in Colloid and Interface Science. 207, p.3-13.