2. for the PRITE

3. is proud to present And Now Here Is The Host... Insert Name Here

4. The categories for today’s Jeopardy on Substance Use will be:

5. Opioids

6. Stimulants

7. Alcohol Use Disorder

8. Criterion A

9. Substance Induced disorders

10. 100 200 300 800 700 500 800 Opioids Alcohol Use Disorders Substance Induced Disorders 100 700 500 700 400 800 600 100 900 300 500 800 Subst Use Disorders Criterion A 100 900 500 400 300 200 300 400 600 800 200 300 600 200 500 400 700 600 200 400 700 600 Stimulants

11. Row 1, Col 1 Opioids can be detected thru a urine drug test for this many hours after administration of the opioid What is 12-36 hours?

12. 1,2 This type of liver disease may occur in up to 90% of persons who inject opioids What is hepatitis C?

13. 1,3 HIV, hepatitis, tuberculosis, and this cardiac related condition are serious medical problems for IV opiate users What is bacterial endocarditis?

14. 1,4 This physical sign of opiate withdrawal is also “seen” in hallucinogen intoxication and stimulant intoxication What is pupil dilation?

15. 1,5 Opioid intoxication may be diagnosed by administering this opioid antagonist challenge What is naloxone (narcan)?

16. 1,6 These two symptoms are associated with more severe opiate withdrawal and are often not seen in routine clinical practice What is piloerection & fever?

17. 1,7 Suboxone is a combination of these two medications What is naloxone (narcan) & buprenorphine?

18. 1,8 Yawning, insomnia, dizziness, diarrhea This one is not part of opiate withdrawal What is lightneadedness? Withdrawal: dysphoria, N/V, muscle aches, lacrimation/rhinorrhea, pupil dilation/piloerection, fever, sweating,

19. 1,9 Signs of opioid intoxication are pupil constriction, drowsiness/coma, impaired attention or memory, and this What is slurred speech?

20. 2,1 This can differentiate PCP intoxication & stimulant intoxication from each other What is a urine drug test? (Clinical picture is similar though rotary nystagmus may be seen in PCP intoxication but not stimulant)

21. 2,2 Cocaine users often use sedative substances--most often this substance--to reduce insomnia, nervousness, and other unpleasant side effects What is alcohol?

22. 2,3 Amphetamine type stimulant users often use sedative substances-- most often this substance--to reduce insomnia, nervousness, and other unpleasant side effects What is marijuana?

23. 2,4 This sign is often present and is a reliable measure of stimulant withdrawal What is a bradycardia?

24. 2,5 Bipolar disorder, schizophrenia, other substance use disorders, and this personality disorder in particular are risk factors for stimulant use disorder What is antisocial personality disorder?

25. 2,6 This type of sample can be used to detect use of a stimulant up to 90 days after the use What is a hair sample

26. 2,7 These two forms of cocaine administration have the most rapid onset of action What is inhalation and injection?

27. 2,8 A speedball is the combination of cocaine and this drug What is heroin?

28. 2,9 Cocaine increases the levels of glutamate and this neurotransmitter What is dopamine?

29. 3,1 In terms of operant conditioning, the alcohol induced buzz/high is this; also tolerance results in the lack of this What is positive reinforcement?

30. 3,2 In terms of operant conditioning, consuming alcohol to stave off alcohol withdrawal symptoms results in this What is negative reinforcement?

31. 3,3 Most substance induced disorders resolve within this amount of time after the cessation of acute withdrawal, the cessation of severe intoxication, or the use of the substance. What is 1 month? (Most improve within days to weeks of abstinence)

32. 3,4 The prevalence of alcohol use disorder in this sex is twice as much as the other What is males? Males ~12%, Females ~5%

33. 3,5 For an individual who has a close relative (parent) with an alcohol use disorder, their risk is this many times higher than normal What are 3-4 times?

34. 3,6 Alcohol metabolizing enzyme genetic polymorphisms result in flushing, palpitations, & possibly more severe reactions in individuals of this race when they consume alcohol What is Asians? Japanese, Chinese, and Koreans are at lower risk for Alcohol Use Disorders

35. 3,7 Elevations in these two lab test results are sensitive indicators of ongoing heavy drinking and can be used to monitor abstinence What is gamma-glutamyltransferase (GGT) and carbohydrate- deficient transferrin (CDT)?

36. 3,8 While elevation of GGT, CDT, and this test indicates a history of heavy drinking, GGT & CDT test may also be useful in detecting a relapse to heavy drinking, but this test is not What is mean corpuscular volume (MCV)? Not useful for monitoring due to long half life of RBC’s

37. 3,9 The patients with bipolar disorder, schizophrenia, & this personality disorder have a markedly high rate of co-morbid alcohol use disorder What is Antisocial Personality Disorder?

38. 4,1 Substance use disorder pts, especially those with severe disorder, have an underlying change in this which persists even beyond detoxification What is brain circuitry?

39. 4,2 Impaired control, Social impairment, Risky use, or Pharmacological criteria Continued use despite persistent or recurring interpersonal problems What is social impairment?

40. 4,3 Impaired control, Social impairment, Risky use, or Pharmacological criteria A desire to cut down or unsuccessful attempts decrease or stop use refers to this Criterion A What is impaired control?

41. 4,4 Impaired control, Social impairment, Risky use, or Pharmacological criteria Pharmacological criteria refers to “putting up” with these two phenomenon What is tolerance & withdrawal?

42. 4,5 Impaired control, Social impairment, Risky use, or Pharmacological criteria Taking the substance in larger amounts or over a longer time period than intended refers to this Criterion A What is impaired control?

43. 4,6 Impaired control, Social impairment, Risky use, or Pharmacological criteria Use in physically hazardous situations or continued use despite knowledge the substance is causing or worsening a medical problem is called this What is risky use?.

44. 4,7 Impaired control, Social impairment, Risky use, or Pharmacological criteria Spending a great deal of time obtaining, using, or recovering from the substance use refers to this Criterion A What is impaired control?

45. 4,8 Impaired control, Social impairment, Risky use, or Pharmacological criteria Failure to fulfill major obligations at work, home, or school refers to this Criterion A What is social impairment

46. 4,9 Impaired control, Social impairment, Risky use, or Pharmacological criteria Craving refers to this Criterion A What is impaired control?

47. 5,1 Caffeine intoxication may induce a sleep disorder or this type of substance induced disorder What is anxiety?

48. 5,2 Marijuana intoxication may induce anxiety disorders, sleep disorders, and this type of substance induced disorder What is Psychotic disorder?

49. 5,3 The hallucinogen phencyclidine may induce psychotic disorders, anxiety disorders, delirium, & this type of substance induced disorders What are mood disorders? (both bipolar & depressive)

50. 5,4 Opioid intoxication may induce sleep disorders, sexual dysfunction, delirium, & this type of substance induced disorder What is depressive disorders?

51. 5,5 Opioid intoxication will not, but opioid withdrawal may induce this type of substance disorder What are anxiety?

52. 5,6 Alcohol & sedative/hypnotic intoxication may both induce the same type of substance disorders except sedative/hypnotic intoxication will NOT induce this What is anxiety? Psychotic, Bipolar, Depressive, Sleep, Sexual Dysfunction, Delirium, Neurocognitive disorders

53. 5,7 Intoxication, but not withdrawal, of stimulants such as cocaine may induce sexual dysfunction, delirium & this type of substance induced disorder What are psychotic disorders?

54. 5,8 Intoxication & withdrawal of stimulants such as cocaine may induce, anxiety, OCD, sleep, & this type of substance induced disorder What is mood? (both bipolar & depressive)

55. 5,9 Inhalants and this type of substance do not cause a withdrawal What is hallucinogens?