1. Successful Grant Submissions at VUMC Beth Berman Administrative Officer of Research Department of Medicine Division of Clinical Pharmacology beth.berman@vanderbilt.edu

2. CLIN PHARM MAJOR SOURCES OF FUNDING:  9 P or U grants (P01s, P60, U01s, U19, U54)  22 R01 or equivalent grants  32 Other (AHA, DOD, NASA, Foundation and Non- Federal) awards  4 K Career Development grants  2 T32 grants  1 K12 Institutional grant  1 VPSD award

3. FEDERAL FUNDING SOURCES National Institutes of Health – http://grants.nih.gov/grants/oer.htm http://grants.nih.gov/grants/oer.htm – Search by Institute Center (IC) Agency, grant mechanism, or research topic Department of Defense/eBRAP – https://ebrap.org/eBRAP/public/Program.htm https://ebrap.org/eBRAP/public/Program.htm – Search by Research Program Opportunities National Science Foundation – http://www.nsf.gov/funding/ http://www.nsf.gov/funding/ – Search by Program Area

4. NON-FEDERAL FUNDING SOURCES proposalCentral – https://proposalcentral.altum.com/ https://proposalcentral.altum.com/ – Search by Sponsor or Program American Heart Association/ grants@heart – http://my.americanheart.org/professional/Research/FundingOpportunities/Funding- Opportunities_UCM_316909_SubHomePage.jsp http://my.americanheart.org/professional/Research/FundingOpportunities/Funding- Opportunities_UCM_316909_SubHomePage.jsp Doris Duke Charitable Foundation – http://www.ddcf.org/Grants/Funding-Opportunities-and-Competitions/ http://www.ddcf.org/Grants/Funding-Opportunities-and-Competitions/ American Diabetes Association – http://professional.diabetes.org/HomeResearchGrantsAndFunding.aspx?hsid=2 http://professional.diabetes.org/HomeResearchGrantsAndFunding.aspx?hsid=2 JDRF – http://jdrf.org/grant-center/grant-opportunities-and-deadlines/ http://jdrf.org/grant-center/grant-opportunities-and-deadlines/ Pivot/ VUMC (formerly FINDGrants) – http://pivot.cos.com/funding_main http://pivot.cos.com/funding_main

5. SELECT YOUR GRANT MECHANISM Grad Students/Post Doc Fellows – Grants available to promote careers in research – Provide salary stipends, travel, lab supplies, etc. – Examples: NIH: F31, F32, T32, Diversity Supplement on Mentor’s Parent Grant AHA: Pre/Postdoctoral Fellowships Susan G. Komen: Postdoctoral Fellowships for Basic/Translational and Clinical Research Areas

6. SELECT YOUR GRANT MECHANISM Junior Faculty – Grants available to promote research independence – Provide salary, travel, and research support, etc. – Examples: NIH: K Career Development Awards Doris Duke: Scientist Development Award VUMC: CTSA KL2, BIRCWH K12, & VPSD

7. SELECT YOUR GRANT MECHANISM Established Faculty – Grants available to support research discoveries – Various levels of funding to support research lab salaries, travel, and other expenses, etc. – Examples: NIH: R03/R21/R01; U01; & P01 DOD: BCRP Innovator Award; LCRP Idea Development Award Foundation Leducq: Transatlantic Networks of Excellence Industry Companies: Baxter, Bristol Myers Squibb, Forest

8. LEARN YOUR FUNDING CYCLES NIH offers 3 funding cycles Activity CodeProgram DescriptionCycle ICycle IICycle III P SeriesProgram Project Grants and Center Grants 1/255/259/25 R01 (New) U01 (New) Research Grants Cooperative Agreements 2/56/510/5 R01 (Renewal/Resub) U01 (Renewal/Resub) Research Grants Cooperative Agreements 3/57/511/5 R21/R03Small Research Grants2/166/1610/16 R21/R03 (Renewal/Resub)Small Research Grants3/167/1611/16 K Series (New)Research Career Development2/126/1210/12 K Series (Renewal/Resub)Research Career Development3/127/1211/12 F Series (All)Individual NRSA4/88/812/8 F31 (All)Individual NRSA (Diversity)4/138/1312/13

9. LEARN YOUR FUNDING CYCLES Non-federal sponsors deadlines vary depending on their funding availability – Check research funding pages often – Sign up for funding alerts/newsletters

10. PREPARE YOUR TEAM Select your scientific key personnel (including consultants) well in advance – Regularly meet to discuss collaborations – Collect updated biosketches Notify your grants manager of future submissions 2-3 months before deadline

11. PREPARE YOUR GRANT NARRATIVES Internal routing starts 10 business days before deadline Any proposal will need the following for internal approval: – Title (Final) – Key Personnel (Final) – Abstract /Relevance Statement (Draft) – Budget (Final) – Budget Justification (Final) – Facilities/Equipment (Draft) Info for Your Grants Admin:  Letters of Support – Y/N  Subcontracts – Y/N  Appendix – Y/N  Animals – Y/N  Human Subjects – Y/N Extra items needed for routing:  Billing Rate # from Starbrite  Planned Enrollment Form  Inclusion Enrollment Form

12. ROUTING YOUR SUBCONTRACTS Grant Proposals Complete Face Page/ LOI Detailed Budget Budget for Entire Proposed Period of Support Budget Justification Scope of Work Biosketch – All Key Personnel Resources Checklist Progress Reports Complete Face Page/ LOI Detailed Budget Budget Justification Scope of Work Other Support for Key Personnel All Personnel Report Checklist

13. ROUTING YOUR GRANT APPLICATION Internal approvals are collected in Coeus PI and Key Personnel are required to submit their Conflict of Interest and/or PI Assurance forms in PEER (proposal will not be approved to submit until this is completed) PI continues to work on science; except no changes to Budget, Key Personnel, or Enrollment Tables

14. SUBMITTING YOUR GRANT APPLICATION Finalize your grant narratives and send to your grants admin OSP prefers for PI to submit 3 days before deadline – Ensures plenty of time to fix any errors Review final documents with your grants admin before you submit Review final submission – NIH via eRA Commons (48 hours prior to deadline) – DOD via eBRAP (see program announcement for cut off date)

15. TIMELINE REVIEW PIGrants AdminAction PreparationSelect collaborators and funding cycle; notify your grants admin Create budget with PI and collect internal routing documents 1-3 months prior to deadline Internal RoutingProvide: Title Key Personnel Abstract /Relevance Budget Budget Justification Facilities/Equipment Prepare Coeus shell for proposal, upload internal routing documents, and finalize the budget 10 days to 1 month prior to deadline Finalizing ProposalSign offs in PEER, finish all grant narratives and send to grants admin Update PIs on what is needed to finalize proposal and work with OSP to get internal approval 10 days to 3 days prior to deadline SubmissionPI sits with grants admin to review all documents and submit proposal Review all document formatting, submit with PI, and verify submission 1 - 3 days prior to deadline

16. COMMON PITFALLS Missing narratives – Cover letter – Letters of support Wrong salary/fringe in budget Missing key personnel Missing eRA Commons username PI not affiliated to VUMC in eRA Commons Narratives over the page limits Using special symbols Research strategy figures are incorrect

17. QUESTIONS?