1. Medical Histology Laboratory Stephen Ernst, Ph.D. Integumentary System

2. Epidermis Dermis Hypodermis Sweat Glands Tendon Skeletal Muscle Blood Vessels Slide 112 Skin FAT

3. Dermal Papillae Epidermal Ridges Reticular Dermis Papillary Dermis Components Of Dermis Components Of Dermis St. Basale (B) St. Spinosum (S) St. Granulosum (G) St. Corneum (C) Components of Epidermis Components of Epidermis C C G G S S B B Nerve Blood Vessels CT NOTE: Presence of nuclei here is abnormal Meissner’s Corpuscle in papilla Meissner’s Corpuscle in papilla Basement Membrane

4. Dermal Papilla Meissner’s Corpuscle Meissner’s Corpuscle Slide 180: Meissner’s Corpuscle Flattened Schwann Cell Laminae encasing nerve fiber endings Flattened Schwann Cell Laminae encasing nerve fiber endings

5. Dermis Hypodermis Nerve Fasicles Secretory Portions SecretoryDucts Sweat Glands Blood Vessels Myoepithelial Processes Myoepithelial Nuclei

6. Pacinian Corpuscle Pacinian Corpuscle (multilayered capsule surrounding central nerve fiber) (multilayered capsule surrounding central nerve fiber) Slide 180: finger tip Epidermis Dermis Hypodermis

7. Slide 108: finger tip Dermis Hypodermis Pacinian Corpuscles

8. Slide 42 Mesentery Pacinian Corpuscle Pacinian Corpuscle Nerve

9. Melanocytes Melanin granules 105-1 Thin Skin 105-2

10. External Root Sheath Sebaceous Gland (Holocrine Secretion) Sebaceous Gland (Holocrine Secretion) Eccrine Sweat Glands Arrector Pili muscle Hair Bulb Connective Tissue (Dermal) Papilla Hair Shaft Canal Hair Shaft Canal 107 Hair Follicle ? ?

11. Slide 109-1 Apocrine Glands Myoepithelial Cell Processes Myoepithelial Cells

12. Apical Secretory Granules Apical Secretory Granules Apocrine Glands Slide 104-2

13. Slide 109-2 Apocrine Sweat Glands (PAS Stain for glycoproteins, mucins, etc.) Secretory Granules Myoepithelial Cells Basement Membrane

14. Slide 265 Nipple and Areola Lactiferous Ducts Sebaceous Glands Smooth Muscle Fasicles Duct opening to surface Duct opening to surface

15. Slide 259: Inactive Mammary Gland Interlobular Connective Tissue Interlobular Connective Tissue Intralobular Connective Tissue Intralobular Connective Tissue Ducts Ductal Cells lining lumen Ductal Cells lining lumen 2nd layer of Myoepithelial Cells 2nd layer of Myoepithelial Cells

16. Slide 258: Active Mammary Gland Interlobular CT Interlobular CT Excretory Duct Excretory Duct Secretory Alveoli in Glandular Lobules Secretory Alveoli in Glandular Lobules (Ductal plus Myoepithelial Cells) (Ductal plus Myoepithelial Cells)