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LIPID METABOLISM
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HYDROLYSIS
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ADIPOSE TISSUE 90% of adipose tissue is tryglycerides It supplies energy. Insulation. Provides minor physical protection Cholestrol storage
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GLYCEROL GLUCOSE PYRUVATE GLYCOLYSIS
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FATTY ACIDS Activation of Fatty Acid
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-OXIDATION Blue box = carbon Red box = acetyl CoA
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-OXIDATION 1.Activation by addition Coenzyme-A 2. carbon oxidized from CH 2 to C=O (ketone) 3.Molecule split into acetyl CoA and Fatty acid 2 carbons shorter 4.Another Coenzyme-A added to shortened Fatty acid
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Each cycle produces 1 acetyl-CoA –18 carbon fatty acid would give 9 acetyl-CoA Cycles required is # of carbons/2 – 1 –18 carbon fatty acid would require 8 cycles Amount of energy from Fatty Acid depends on length of carbon chain –18 carbon fatty acid would 120 ATP
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LIPOGENESIS Making triglycerides from glycerol and fatty acids Anabolic process Fatty acids made linking 2 carbon acetyl groups (from acetyl CoA) to growing chain Most Fatty acids have an even number of carbons
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ESSENTAIL FATTY ACIDS Those needed by the body, but not synthesized within the body in adequate amounts. Found in fish and some plants
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GLUCOSE TRIGLYCERIDES PYRUVATE GLYCEROL ACETYL-CoA glycolysis gluconeogenesis -oxidation lipogensis
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