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Modified over 5 years ago
Principles of Immunology Tumor Immunology 4/25/06
Word/Terms List AFP Benign Carcinoma CEA Leukemia Lymphoma Malignant Metastasis Neoplasm Oncogene Sarcoma Transformation TSTA
Tumor Immunology Benign vs. malignant tumors Types of neoplasms Carcinomas Leukemias/lymphomas Sarcomas
Cell Transformation Characteristics Nutritional changes Lack of contact inhibition Immortality
Chemicals and Cancer Mitogens Mutagens Carcinogens
Genes and Cancer Oncogenes Proto-oncogenes
Tumor-specific Transplantation Antigens Origin of TSTAs Point mutations Expressed by germ line cells Expressed by specific cell types Over expressed Post translation changes Viral oncogenes
Oncofetal Antigens Alpha fetoprotein (AFP) Carcinoembryonic antigen (CEA)
Tumors of the Immune System Leukemias ALL AML CLL CML Lymphomas
Tumors and Viruses Hepatitis B Human papilloma virus(HPV) Epstein Barr Virus
Tumors and Evasion of the Immune System Low immunogenicity Modulation by antibodies Tumor secreted suppressors
Immune Response to Tumors Cells NK CTLs Macrophages Cytokines Interferon TNF
Immunotherapy Against Tumors ADCC Toxin conjugation Radionuclide conjugation
Evading Immune Responses and Tumor Immunology
Immunology in Head and Neck Cancer Stephanie Cordes, MD Christopher Rassekh, MD February 11, 1998.
Immunological aspect of tumor
Immunity to tumors Tumor antigens
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