1. Elective Open Repair of Abdominal Aortic Aneurysms (AAA): A Systematic Review of Risk Factors for AAA Associated Morbidity and Mortality Outubro 2007 Turma 5 - 1º ano Mestrado Integrado em Medicina, FMUP

2. Outline AAA definition Major risk factors for AAA Open repair surgery Postoperative complications Study development

3. Abdominal Aortic Aneurysm The abdominal aorta is located below the renal arteries, but above the iliacs arteries AAA is an abnormal widening of artery, more than 1.5 times its diameter

4. Abdominal Aortic Aneurysm The abdominal aorta is located below the renal arteries, but above the iliacs arteries AAA is an abnormal widening of artery, more than 1.5 times its diameter

5. Risk Factors Smoking Family history of AAA Chronic obstructive pulmonary disease Previous vascular surgery Hypertension Atherosclerosis Age>50 y.o. and male gender

6. Open Repair Surgery Invasive surgery procedure with insertion of a prosthetic tube-like graft Two types: –Transperitoneal –Left retroperitoneal

7. Postoperative Complications Cardiac events Haemorrhage Pulmonary insufficiency Renal failure Gastrointestinal ischemia and/or dysfunction Erectile dysfunction Graft infection

8. Study Development

9. Articles Search Query: Abdominal Aortic Aneurysm Open Repair Mortality Risk factors (("mortality"[Subheading] OR "mortality"[MeSH Terms] OR mortality[Text Word]) AND ("abdominal aortic aneurysm"[Text Word] OR "aortic aneurysm, abdominal"[MeSH Terms] OR aaa[Text Word]) AND elective[All Fields] AND open[All Fields]) AND ((("wound healing"[TIAB] NOT Medline[SB]) OR "wound healing"[MeSH Terms] OR repair[Text Word]) OR ("surgery"[Subheading] OR "operative surgical procedures"[Text Word] OR "surgical procedures, operative"[MeSH Terms] OR "surgery"[MeSH Terms] OR surgery[Text Word])) NOT endovascular[All Fields]

10. Inclusion/Exclusion Criteria Articles contemplating emergency open AAA repair Other languages than English, French, Spanish or Portuguese Other types of articles such as reviews, letter to editor or comments; …

11. Data extraction and statistical analysis Review of all included studies Extract all important data Start analysis