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Figure The citric acid cycle in context.

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Presentation on theme: "Figure The citric acid cycle in context."— Presentation transcript:

1 Figure 11.01 The citric acid cycle in context.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure The citric acid cycle in context.

2 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Figure Structor of the E2 core of the pyruvate dehydrogenase complex from B. stearothermophilus.

3 Figure 11.03 Thiamine pyrophosphate (TPP).
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Thiamine pyrophosphate (TPP).

4 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Figure Lipoamide.

5 Figure 11.05 Flavin adenine dinucleotide (FAD).
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Flavin adenine dinucleotide (FAD).

6 Figure 11.06 Reactions of the pyruvate dehydrogenase complex.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Reactions of the pyruvate dehydrogenase complex.

7 Figure 11.07 Reactions of the citric acid cycle.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Reactions of the citric acid cycle.

8 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Citrate synthase

9 Figure 11.08 Conformational changes in citrate synthase from chicken.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Conformational changes in citrate synthase from chicken.

10 Figure 11.09 The citrate synthase reaction.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure The citrate synthase reaction.

11 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Aconitase

12 Isocitrate dehydrogenase
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Isocitrate dehydrogenase

13 α-Ketoglutarate dehydrogenase
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. α-Ketoglutarate dehydrogenase

14 Figure 11.10 Fates of carbon atoms in the citric acid cycle.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Fates of carbon atoms in the citric acid cycle.

15 Figure 11.11 The succinyl-CoA synthetase reaction.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure The succinyl-CoA synthetase reaction.

16 Figure 11.12 Substrate binding in succinyl-CoA synthetase.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Substrate binding in succinyl-CoA synthetase.

17 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Fumurase

18 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Malate dehydrogenase

19 Figure 11.13 Regulation of the citric acid cycle.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Regulation of the citric acid cycle.

20 Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc.
Figure Citric acid cycle intermediates as biosynthetic precursors.

21 Figure 11.17 The citrate transport system.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure The citrate transport system.

22 Figure 11.18 Anaplerotic reactions of the citric acid cycle.
Essential Biochemistry by Pratt & Cornely, © 2004 John Wiley & Sons, Inc. Figure Anaplerotic reactions of the citric acid cycle.


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