1. HOW DOES BLOOD CLOT ROSHNI KULKARNI MD Professor, Department of Pediatrics & Human Development, Michigan State University USHA M REDDY MD Visiting Scholar, MSU Multimedia, Graphics, Webpage Consultant BRUCE L EVATT MD Director, Hematologic Disease Branch Center for Disease Control (CDC )

2. HEMOSTASIS How does blood clot –Hemostasis overviewHemostasis overview –Platelet activationPlatelet activation –Extrinsic pathwayExtrinsic pathway –Intrinsic pathwayIntrinsic pathway –Tissue factor pathwayTissue factor pathway Platelet –Platelet ProductionPlatelet Production –Platelet MembranePlatelet Membrane –Platelet BodyPlatelet Body –Platelet GranulesPlatelet Granules –Platelet role in HemostasisPlatelet role in Hemostasis

3. HOW DOES BLOOD CLOT - OVERVIEW

4. PLATELET ACTIVATION

5. EXTRINSIC PATHWAY

6. INTRINSIC PATHWAY

7. TISSUE FACTOR PATHWAY

8. PLATELET

9. PLATELET PRODUCTION

10. THE PLATELET MEMBRANE

11. THE PLATELET BODY

12. THE PLATELET GRANULES

13. THE PLATELET ROLE IN HEMOSTASIS

14. END