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Tucker et al. 2006. Am J Clinical Nutrition Femur Bone Mineral Density Bell et al. 1977 J of Nutrition High Phosporus Diet Vs. Control Diet Population Survey (~2,500 people) Questionnaire with X-RAY for BMD
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How does high Phosphorus = Lower BMD? Phosphate (PO 4 3-) Ca 2+ or Mg 2+ or Na + & PO 4 3- H + or 2H + & PO 4 3- 50% 40% Ca 2+ PTH released Bone breaks down releasing Ca2+ Kidney reabsorbs Ca2+ Intestines uptake more Ca2+ In Plasma
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Hydroxyapatite (Ca 5 (PO 4 ) 3 (OH) = Storage of Calcium in Bone Bone Resorption Hydrochloric Acid = Dissolve Mineral Acid Proteases (Enzymes) = Digest Bone Matrix Protiens (Collagen, etc) Bone Structure
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