Download presentation
Presentation is loading. Please wait.
1
From gene to protein DNAPhenotype RNA ReplicationTranscription *Transcription Translation *Translation *Gene The flow of information: 1. Storage 2. Replication 3. Expression DNA as the Genetic Material Protein 2. Replication
2
Review nucleotide structure:
3
Structural analysis of DNA
4
DNA Replication and Synthesis Complementarity ”It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism … “ Mode of DNA Replication Semiconservative
5
*Overview: DNA replication *Complementarity determines which nucleotide will be added *Chain elongation in a 5’-to-3’ direction
6
Initiation *Primase *Strands must separate Helicases SSBPs DNA gyrase *Two strands of a double helix are antiparallel Continuous DNA synthesis = leading Discontinuous DNA synthesis = lagging
7
A large team of enzymes carry out DNA replication: Helicases SSBPs DNA gyrase Elongation: Association of polymerase Sliding clamp Primase DNA synthesis (DNA pol) Primer removal and replacement (DNA pol) Ligase closes the gaps
8
The Molecular Basis of Heredity
9
The Flow of Genetic Information in the Cell
10
The Genetic Code
Similar presentations
© 2024 SlidePlayer.com Inc.
All rights reserved.