1. Trend of PCB Use in Japan Total 58,000t Amount of PCB use (t)

2. PCB product use in Japan Ar-1242 1248 1254 1260 1969-1971 KC-300 400 500 600

3. KC300 KC400 KC500 KC600 Japan Homologue pattern reflects product use

4. Daily variation of PCDD/Fs and PCBs in ambient air

8. Daily variation of Dioxin Concentration

9. Time trend of PCB levels in ambient air (log scale)

10. Time trend of PCBs concentration in ambient air (pg/m 3 ) Time trend of PCBs concentration in ambient air (ng/m 3 ) (pg/m 3 ) (ng/m 3 ) Ambient air

11. PCB 使用量 (t) PCB 濃度 (ng/m 3 )

12. PCB levels and Homologue profiles in Environmental samples

13. PCB levels (2002, 環境省 ) Air Sediment Water Biota 0.01-1ng/m 3 0.1-10ng/L 0.05-800ng/g-dry0.1-800ng/g-wet

14. HCB & PCB levels (2002, 環境省 ) Air Sediment Water Biota 0.01-1ng/m 3 0.1-10ng/L 0.05-800ng/g-dry0.1-800ng/g-wet 0.1-5ng/m 3 0.01-1ng/L 0.01-1ng/g0.01-10ng/g HCB PCB

15. PCB の同族体分布 （平均組成）

16. Air Water Bird Fish Shellfish Sediment 大気 水質 魚 貝類 底質 鳥

17. Air Water Bird 0 5 10 15 20 25 30 35 40 45 50 abundance(%) Human blood Breast milk

18. Homologue profiles of PCB in sealant and air Sealant （ Low-Cl) Sealant （ High-Cl) Room air

19. Source estimation KC300 KC400 KC500 KC600 Sediment A Sediment B Ship paint N.C.P. Insulator capacitor

20. PCB の異性体分析

21. Matsumura et al, J. Env. Chem. (2002) GC/MS-SIM chromatogram of TrCB (HT8-PCB) PCB product 13 C-TrCB

22. Matsumura et al, J. Env. Chem. (2002) GC/MS-SIM chromatogram of PeCB (HT8-PCB) 13 C-PeCB PCB product

23. Congener profiles of PCBs in environmental samples

24. Congener profiles of PCBs(Di-, Tri-) in environmental samples

25. Congener profiles of TrCB,TeCB in human and combustion sample (A)

26. PCB congeners predominant in human samples (TrCB, TeCB) PCB product Combustion Breast milk Combustion PCB product Breast milk

27. Congener profiles of TrCB,TeCB in combustion sample (B)

28. (stack gas) TrCB TeCB #68 #51 #47 24-26 24-24 24-35

29. Congener profiles of PCBs in environmental and human samples

30. Congener profiles of PCBs(Hexa-) in environmental and human samples

31. Congener profiles of PCBs(Hepta-) in environmental and human samples

32. ＃ 28 ＃ 31 ＃ 74 ＃ 80 ＃ 99 ＃ 118 ＃ 153 ＃ 138 ＃ 163/ ＃ 164 ＃ 187 ＃ 180 ＃ 170 Tri-CBs Tetra-CBs Penta-CBs Hexa-CBs Hepta-CBs Chromatogram of PCB in human blood （ 3~7Cl ） Hirai et al, (2003) Organohalogen compounds #187 #180 #153 #138 #74 #99 #118 #28 245-2345 245-245 245-234 245-34 245-2356 245-4 245-24 24-4

33. Isomer distribution (P 7 CB, Port Island in June,2001) KC300-600 Sea Water Mussel Intensity #174 #180 #170

34. Isomer distribution (O 8 CB, Port Island in June, 2001) KC300-600 Sea Water Mussel Intensity #202#201 #196 #203#194#195 #199

35. Congener profiles of PCBs in environmental and human samples

36. PCB 製品 ヒト #74 #66 245-4 24-34 #99 #101 245-24 245-25 #146 #149 245-235 245-236 PCB 製品 ー > 環境（大気、水質、 底質） ー > 生物（貝、魚、 鳥） ー > ヒト

37. Congener profiles of PCBs in human samples (pooled blood)

38. (n=24) CongenersMean ± 2S.D. Existence Ratio* (BZ#)(ng /g-lipid)(%) #153 28.0 ± 22.3 #18014.9 ± 16.611.8 #13810.4 ± 9.28.3 #1878.3 ± 8.56.6 #1186.9 ± 5.95.5 #163,1646.4 ± 6.25.1 #994.7 ± 4.23.8 #744.6 ± 2.63.6 #1464.1 ± 3.73.3 #1703.8 ± 4.13.0 #1562.8 ± 3.02.3 Sum75.6 * Mean is compare to total PCBs level Levels of the predominant PCB congeners in human blood Hirai et al, (2003) Organohalogen compounds 245-2345 2345-234 245-245 245-234 245-4 245-24 245-34 245-2356 245-235 2345-34 22.3 34.1 42.4 49.0 54.5 59.6 63.4 67.0 70.3 73.3 75.6 cumulative (%)

39. human milk/adipose tissue #74 (2,4,4',5-) #99 (2,2',4,4',5-) #118 (2,3',4,4',5-) #153 (2,2',4,4',5,5'-) #138 (2,2',3,4,4',5'-) #187 (2,2',3,4',5,5',6-) PCB congeners predominant in human samples

40. transformer and capacitor : 370,000 stabilizer for Flu. lamp : 2,400,000 non carbon paper : 644,000 kg waste sludge : 117,000 kg waste : 105,000,000 kg other equipments : 33,000 waste PCB etc : PCB waste stock

41. transformer and capacitor : 370,000 stabilizer for Flu. lamp : 2,400,000 non carbon paper : 644,000 kg waste sludge : 117,000 kg waste : 105,000,000 kg other equipments : 33,000 waste PCB etc :

42. PCB waste stock transformer and capacitor : 370,000 stabilizer for Flu. lamp : 2,400,000 non carbon paper : 644,000 kg waste sludge : 117,000 kg waste : 105,000,000 kg other equipments : 33,000 waste PCB etc :

43. Congener profiles of PCB in human sample

44. 1973 2000 PCB congener composition in human breast milk #187 #180 #153 #138 #74 #99 #118 #187 #180 #153 #138 #74 #99 #118

45. Salmon Breast milk PCB congener composition in human breast milk PCB congener composition in salmon #187 #180 #153#138 #66 #101 #118 #187 #180 #153 #138 #74 #99 #118