1. Tobacco - Inside the Body ©Photographs courtesy of Manchester University Pathology Department

2. Human female chromosome map (XX). Alcohol and nicotine addiction may be in the genes

3. There is accumulation of carbon (smoke) within the walls of these air sacs in the lungs. This makes the air sacs inelastic and it is difficult for air to get out of the lungs (Emphysema)

4. Clubbing of the fingers is a common condition which may indicate cancers, liver diseases and lung disease

5. Clubbed fingers - a sign of heart disease

6. Focal dust emphysema is commonest in cigarette smokers and coal miners.The black colour in this lung is due to cigarette smoke

7. Cells lining the bronchus- here there are no microscopic hairs needed to move dirt and dust out of the lungs- they have been destroyed by the nicotine

8. Cells lining the wind pipes, the large nuclei are in cancer cells spreading through the lungs

9. Lung tissue blackened by smoke and showing large spaces that cause emphysema

10. Emphysema- these large spaces are due to the breakdown of the air sacs in the lungs

11. Lungs: The picture on the left is of emphysema (large air sacs) and the picture on the right is of normal lung – the picture on the left was came from a smoker.

12. The air sacs in the centre of the lung tissue in the picture have broken down. The black dots are smoke particles lodged in the tissues- this condition is emphysema. (28)

13. Cancer of the bronchus that has spread into the lungs

14. A blue colouration occurs when blood circulation is poor such as heart failure and circulation damaged caused by cigarettes

15. Most amputations in the United Kingdom are a direct result of smoking

16. This man is a heavy smoker (see nicotine stained fingers) and has led to vascular disease which has resulted in a blood clot on one of his fingers on his right hand

17. Damaged toes due to poor blood circulation- will lead to amputation

18. Amputated fingers- a result of damage to blood vessels due to smoking

19. Franks sign - an ear lobe crease thought to be indicative of heart problems, a possible sign of a smoking related disease

20. Franks sign- ear lobe crease a sign of heart disease

21. Fluid collecting in the tissues, note the dent where somebody has pressed on top of the hand- a sign of heart failure – probable cause - smoking

22. Heart:This slice is also through the heart (compare it to the next slide) The left side is towards the right of the image as you look at it, and shows a white area of in the heart wall. This is tissue, which has died due to lack of blood supply

23. Heart: The left ventricle is towards the left of the screen, and shows enormous thickening of the wall, particularly in relation to the small cavity. The heart is almost twice the size it should be, as it has had to work much harder than normal.

24. Expansion of finger ends- associated with chronic breathing and heart problems, again problems associated with smoking

25. Expansion of finger ends- associated with chronic breathing and heart problems

26. Cancer of oesophagus- this is where the oesophagus meets the stomach

27. Cancer of the kidney- the cancer growth is the white tissue

28. Bladder cancer - the bladder is a hollow bag for storing urine- here it is cut open showing a large cancerous growth inside

29. Cancer of the pancreas

30. Stomach ulcers (dark brown) - alcohol and smoking are factors

31. Stomach ulcers (dark brown)- alcohol and smoking are factors. The stomach is cut open.