1. Dermatophytosis Cutaneous mycosis Dermatomycosis Yeast Saprophytes
Systemic mycosis
Dermatophytes
Dermatophytosis

2. Dermatophytosis
Definition
Greek
English
Persian
Dermatophytes

3. Dermatophytosis Dermatophyte Sexual Asexual Trichophyton Microsporum
Arthroderma
Asexual
Macroconidia
Trichophyton
Microsporum
Epidermophyton

4. Dermatophytosis Trichophyton Microsporum Epidermophyton Cylinder
Spindle
Epidermophyton
Club

5. Dermatophytosis Trichophyton Microsporum Epidermophyton
T.rubrum, T.mentagrophytes, T.violaseum, T.schoenleinii, T.verrucosum
Microsporum
M.canis, M.gypseum
Epidermophyton
E.floccosum

6. Dermatophytosis Geophilic Zoophilic Anthropophilic M.gypseum
M.canis, T.verrucosum
Anthropophilic
T.rubrum, T.violaseum, T.schoenleinii E.floccosum

7. Dermatophytosis Tinea capitis Tinea barbae Tinea cruris Tinea pedis
Tinea mannum
Tinea corporis
Tinea unguium

8. Tinea capitis Definition Trichophyton & Microsporum
Clinical manifestation
Crust
Krion
Scatulum
Age
Genus
Ectothrix, Endothrix, Favus

9. Ectothrix Outside Krion Cuticle Gray patch Age Genus After maturation
M.canis, M.audouinii, T.verrucosum, T.mentagrophytes

10. M.canis Zoophilic Dog & cat Yellow Microconidia Few Macroconidia
Thick wall
Knob

11. M.gypseum
Geophilic
Favus( may be)
Red
Don't have knob

12. Endothrix Inside Cuticle Black dot, bald patch Age Genus
After maturation
Anthropophilic
T.violaceum, T.sudanense, T.tonsuranse

13. Favus Hyphae (Air canal) lustreless scatulum Age Genus
After maturation
Cheesy or mouse judder
T.schoenlinii

14. T.schoenleinii
Anthropophilic
Favic chandelier

15. Differential diagnosis
Alopecia
Trichotillomania

16. Laboratory diagnosis Sampling Culture Direct Sesser Scc(2)
Ectothrix, Endothrix, Favus

17. Dermatophytosis
Tinea capitis

18. Dermatophytosis
Tinea capitis

19. Dermatophytosis
Tinea capitis

20. Dermatophytosis
Tinea capitis

21. Dermatophytosis
Tinea capitis

22. Dermatophytosis
Tinea capitis

23. Dermatophytosis
Tinea capitis

24. Dermatophytosis
Tinea capitis

25. Dermatophytosis
Tinea capitis

26. Dermatophytosis
Tinea capitis

27. Dermatophytosis
Tinea capitis

28. Dermatophytosis
Tinea capitis

29. Dermatophytosis
Tinea capitis

30. Dermatophytosis
Tinea capitis

32. Tinea barbae Definition Genus Age Beard & mustache Zoophilic
T.verrucosum, T.mentagrophytes

33. T.Verrucosum
Zoophilic
Cow & cattle
37°
Chlamydioconidia

34. Tinea barbae Clinical manifestation Circular Scaling Vesicle
Ectothrix, Endothrix, Favus

35. Dermatophytosis
Tinea barbae

36. Dermatophytosis
Tinea barbae

37. Dermatophytosis
Tinea barbae

38. Tinea barbae
Differential diagnosis
Alopecia
Laboratory diagnosis

39. Tinea cruris Definition Sever itch With tinea pedis Ecology Male
Anthropophilic
E.floccosum, T.mentagrophytes, T.rubrum

40. E.floccosum Anthropophilic Do not have microconidia Macroconidia
2-4 or 3-5 cells
E.stoackdaleae

41. Tinea cruris Clinical manifestation Maculae Red Vesicle Erythematic
Itch
Don't involve pubis

42. Dermatophytosis
Tinea cruris

43. Dermatophytosis
Tinea cruris

44. Dermatophytosis
Tinea cruris

45. Dermatophytosis
Tinea cruris

47. Tinea pedis
Athlet ́s foot
Age
Shoes, warm, moisture
T.M, T.R, E.F

48. Tinea pedis Clinical manifestation Chronic intertrigenous
Chronic papulosquamous hyperkeratotic
Vesicular or sub acute
Acute ulcerative

49. Tinea pedis Chronic intertrigenous Common type White scale
Between 5,4 & 4,3
Itch

50. Dermatophytosis
Tinea pedis

51. Dermatophytosis
Tinea pedis

52. Dermatophytosis
Tinea pedis

53. Tinea pedis Chronic papulosquamous hyperkeratotic T.rubrum
Moccasin foot
Scaling

54. Dermatophytosis
Tinea pedis

55. Dermatophytosis
Tinea pedis

56. Tinea pedis
Vesicular or sub acute
T.M, T.R
Id reaction
Dermatophytid

57. Dermatophytosis
Tinea pedis

58. Dermatophytosis
Tinea pedis

59. Dermatophytosis
Tinea pedis

60. Dermatophytosis
Tinea pedis

61. Dermatophytosis
Tinea pedis

62. Tinea pedis
Acute ulcerative
Bacteria
Treatment is difficult

64. Tinea mannum
Definition
Position
Clinical manifestation
Agents

65. T.mentagrophytes 4 strain Interdigital is anthropophilic
Erinaci is zoophilic (-)
Hair penetration
DW ml
10% yeast extract D
Horse hair
25° to 4 week

66. T.mentagrophytes
Hyphae
Spiral or coil
Macroconidia
Club

67. T.rubrum
Anthropopilic
CMA
Urease
Hair
Sorbitol

68. Tinea corporis Definition Trichophyton Microsporum Body reaction
Contagious
Direct & indirect
Annular
Center & margin
Vesicle
T.M, T.V

69. Dermatophytosis
Tinea corporis

70. Dermatophytosis
Tinea corporis

71. Dermatophytosis
Tinea corporis

72. Tinea corporis Tinea imbricata T.concentricum Anthropophilic
Clinical manifestation
Genetic
Ecology

73. Tinea imbricata

74. Tinea imbricata

75. Laboratory diagnosis Tinea cruris, pedis, mannum & corporis Sampling
Direct
Culture

77. Tinea unguium Definition Onychomycosis Yeast Saprophytes
scopulariopsis

78. Tinea unguium
Leukonychia mycotica
invasive

79. Dermatophytosis
Tinea unguium

80. Dermatophytosis
Tinea unguium

81. Dermatophytosis
Tinea unguium

82. Dermatophytosis
Tinea unguium

83. Dermatophytosis
Tinea unguium

84. Dermatophytosis
Tinea unguium

85. Dermatophytosis
Tinea unguium

86. Dermatophytosis
Onychomycosis

87. Dermatophytosis
Onychomycosis

89. Dermatophytosis
Treatment
Griseofulvine
Terbinafin

90. Factors involved Regional Individual Heat Humidity Local Systemic
Hyperhydrosis
Local steroid
Systemic
Immunosuppression
Corticosteroid

91. Antigens
Complex structure
Cell wall Antigen
Enzymes

92. Cell wall Antigen
Chitin
Glucan
Mannoprotein
Galactomannan

93. Enzymes Keratinase Elastase Collagenase Proteinase Metalloproteinase
Serine proteinase

94. Immune system
Skin
Unsaturated transferin
α2 macroglobulin

95. Skin
Physical & chemical barrier
Innate immunity
Low humidity UV
Flora

96. skin Keratinization & Epidermal Proliferation Antifungal agent
Increase turn over
Shedding
Antifungal agent
Saturated fatty acid

97. Immune system Unsaturated transferin α2 macroglobulin Free iron
e chain transport
Krebs cycle
α2 macroglobulin
Keratinase inhibition

98. The inflammatory response
Reverse relationship
Inflammatory & chronic
Anthropophilic
Inflammation low
Infection permanent
Zoophilic & geophilic
Inflammation sever
Infection self limitation

99. The inflammatory response
Dermatophyte → complement → chemo tactic
alternative C5a
Neutrophile Activation
Myeloproxidase
Oxidative
Hydrogen peroxide
Super oxide
Defensin
Nonoxidative
Catepsin
Lactoferin

100. Humeral immunity
Types of Ab
IgG, IgM, IgA & IgE
Nonprotective

101. Cell mediated immunity
Deficiency in CMI
Permanent infection
Recurrent infection

102. Regulation Of Immune Response
Mannan
Immune inhibitor
Blocking of monocyte receptors
In vitro
Inhibition of lymphoblast production
Inhibition of lymphocyte proliferation

103. Immunization
T.verrucosum
LFT-130
Drug therapy