1. Malaria By: Keri Gregory

2. What is Malaria??? Malaria is an infectious disease that is cause by a protozoan parasite.

3. Plasmodium Plasmodium is the name of the parasite that causes the disease Malaria. Plasmodium is the name of the parasite that causes the disease Malaria. The plasmodium parasite feeds off of red blood cells contents. Causing the red blood cell to eventually burst. The plasmodium parasite feeds off of red blood cells contents. Causing the red blood cell to eventually burst. The plasmodium parasite enters the human though the bite of a Anopheles mosquito. The plasmodium parasite enters the human though the bite of a Anopheles mosquito. After the plasmodium parasite finishes its cycle in the human it can infect other mosquitoes that bite the infected human. After the plasmodium parasite finishes its cycle in the human it can infect other mosquitoes that bite the infected human.

4. Symptoms of Malaria Fever Fever Chills Chills Headache Headache Sweats Sweats Fatigue Fatigue Nausea and vomiting Nausea and vomiting

5. Life Cycle of Malaria

6. Stages of Malaria Stage 1: Anopheles mosquito inoculates sporozoites into the human host. Stage 1: Anopheles mosquito inoculates sporozoites into the human host. Stage 2: The sporozoites then infect liver cells of the host and mature into schizonts. Stage 2: The sporozoites then infect liver cells of the host and mature into schizonts. Stage 3: The schizonts rupture and release merozoites. Stage 3: The schizonts rupture and release merozoites. Stage 4: Merozoites travel through the blood stream to infect red blood cells. Stage 4: Merozoites travel through the blood stream to infect red blood cells.

7. Stages of Malaria Stage 5: In the red blood cells, the ring stage trophozoites mature into schizonts, which rupture releasing merozoites. Stage 5: In the red blood cells, the ring stage trophozoites mature into schizonts, which rupture releasing merozoites. Stage 6: Some parasites differentiate into sexual erythrocytic stages (gametocytes). Stage 6: Some parasites differentiate into sexual erythrocytic stages (gametocytes). Stage 7: Blood stage parasites are responsible for the clinical manifestations of the disease. Stage 7: Blood stage parasites are responsible for the clinical manifestations of the disease. Stage 8: The gametocytes are then ingested by an Anopheles mosquito as it feeds on the infected host. Stage 8: The gametocytes are then ingested by an Anopheles mosquito as it feeds on the infected host.

8. Stages of Malaria Stage 9: The parasites’ multiply in the mosquito which is known as the sporogonic cycle. Stage 9: The parasites’ multiply in the mosquito which is known as the sporogonic cycle. Stage 10: While in the mosquito's stomach, the microgametes penetrate the macrogametes generating zygotes. Stage 10: While in the mosquito's stomach, the microgametes penetrate the macrogametes generating zygotes. Stage 11: The zygotes in turn become motile and elongated which invade the midgut wall of the mosquito where they develop into oocysts. Stage 11: The zygotes in turn become motile and elongated which invade the midgut wall of the mosquito where they develop into oocysts. Stage 12: The oocysts grow, rupture, and release sporozoites, which make their way to the mosquito's salivary glands and then inoculation of the sporozoites into a new human host. Stage 12: The oocysts grow, rupture, and release sporozoites, which make their way to the mosquito's salivary glands and then inoculation of the sporozoites into a new human host.

9. Websites http://www.medterms.com/script/main/art.a sp?articlekey=4255 http://www.medterms.com/script/main/art.a sp?articlekey=4255 http://en.wikipedia.org/wiki/Malaria http://www.webmd.com/a-to-z- guides/malaria-symptoms http://www.webmd.com/a-to-z- guides/malaria-symptoms http://www.dpd.cdc.gov/dpdx/HTML/Malaria. htm http://www.dpd.cdc.gov/dpdx/HTML/Malaria. htm