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Digestive System
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introduction
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Overview Gastrointestinal Tract (GI Tract) – from mouth to anus
Accessory organs – teeth, tongue, salivary glands, liver, gallbladder, pancrea s
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Functions Ingestion Secretion – H20, enzymes, acid, buffers
Mixing and propulsion – peristalsis Digestion – mechanical and chemical breakdown Absorption Defecation
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structures
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Mouth, Pharynx & Esophagus
Mouth includes teeth, tongue, salivary glands Pharynx – throat; swallowing reflex Esophagus – muscular tube; transports food to the stomach; some absorption
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Stomach J-shaped enlargement of the GI tract Gastric Juice:
Mucus Pepsinogen HCl Intrinsic factor Chyme: thick liquid of gastric juice and food
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Stomach 4 Layers of stomach wall Mucosa Secretory Cells
Rugae – folds of stomach wall Columnar epithelium – secretes mucus Secretory Cells Mucus cells Parietal Cells – HCl and Intrinsic factor (vit. B12 absorption) Chief cells – secrete pepsinogen G cells – secrete gastrin
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Stomach Muscularis 3 layers of muscle Serous Membrane
Forms the greater omentum and mesentery
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Small Intestine 3 sections: duodenum, jejunum, ileum
Most of digestion and absorption takes place here Absorptive cells in the microvilli Absorption of sugars, amino acids, H2O, lipids, vitamins Digestive enzymes come from pancreas and small intestine
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Small Intestine Digestive enzymes: Maltase, sucrase, lactase Lipase
Absorption: Simple sugars, amino acids, ions, H2O, lipids, and vitamins
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Large Intestine 1st section at opening of ileum – cecum; appendix attached 4 regions: ascending, transverse, descending, and sigmoid colon Final stage of digestion (work of bacteria) Absorption of H2O, vitamins Chyme → feces → defecation (elimination)
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Pancreas Pancreatic juice: H2O, salts, HCO3-, enzymes Enzymes:
Amylase; breaks down starches Trypsin; breaks down proteins (inactive form) Lipase; breaks down fats
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Liver & Gallbladder Bile: emulsifies large lipid globules; stored in gallbladder Functions: Carbohydrate metabolism – blood glucose levels Lipid metabolism – cholesterol production, etc. Protein metabolism – ATP production, converting ammonia into urea, plasma protein production
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Liver & Gallbladder Functions (continued)
Processes drugs and hormones; detox center Stores minerals and vitamins Activates vitamin D
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