Presentation is loading. Please wait.

Presentation is loading. Please wait.

Mortality benefit from reduction in sodium consumption 1 Hypertension affects one-third of the US population, of which less than half have their blood.

Similar presentations


Presentation on theme: "Mortality benefit from reduction in sodium consumption 1 Hypertension affects one-third of the US population, of which less than half have their blood."— Presentation transcript:

1 Mortality benefit from reduction in sodium consumption 1 Hypertension affects one-third of the US population, of which less than half have their blood pressure under control. Studies have demonstrated a positive association between high sodium intake and elevated blood pressure. Less than 12% of adults meet the recommended amount of sodium intake (less than 1500 mg/d): the daily sodium intake in the US has averaged 3600 mg/d over the last 20 years. (80% coming from processed and commercially prepared foods) 1. Coxson PG, Cook NR, Joffres M, et al. Mortality benefits from US population-wide reduction in sodium consumption: projections from 3 modeling approaches. Hypertension. 2013;61:564-570.

2 Collaborative modeling of the effect of population-wide sodium intake reduction on health Effects of a sodium reduction intervention on cardiovascular disease (CVD) were estimated based on the results of the extended follow-up of a randomized clinical trial with sodium restriction intervention. 1 Three scenarios regarding salt restriction were studied: -Scenario A: gradual uniform reduction of salt absorption achieving 40% reduction within 10 years. -Scenario B: immediate 40% reduction in sodium consumption sustained for 10 years. -Scenario C: immediate reduction to 1500 mg/d (recommended level) sustained for 10 years. 1. Cook NR, Cutler JA, Obarzanek E. et al. Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP). BMJ. 2007;334:885-888.

3 Ten-year estimate of cardiovascular disease for each scenario Projected deaths with current sodium consumption95% Confidence interval CHD deaths3800 Stroke deaths821 Major CVD deaths4600 Total deaths15 000 Total person-years of life1 567 000 Death prevented and life-years added Scenario A CHD deaths38314-697 Stroke deaths833-150 Major CVD deaths51619-939 Total deaths50519-917 Total person-years of life added181767-3361 Scenario B CHD deaths67126-1185 Stroke deaths1456-256 Major CVD deaths90435-1597 Total deaths87434-1543 Total person-years of life added4445173-7841 Scenario C CHD deaths90937-1540 Stroke deaths1908-324 Major CVD deaths121549-2062 Total deaths117448-1992 Total person-years of life added5970243-10 119 CHD, coronary heart disease; CVD, cardiovascular disease Current lifestyle Expected effect of the different strategies of salt consumption reduction

4 Percent change in mortality and cardiovascular events over 10 years CHD, coronary heart disease; CVD, cardiovascular disease

5 Conclusion This study suggests a substantial benefit for the US population from drastic reduction of salt consumption, Although scenarios B and C are the most effective at protecting individuals against salt-related cardiovascular disease, the strategy of scenario A (40% reduction over a period of 10 years) seems more accessible and should encourage health authorities to support continuous effort aimed at achieving reduction in sodium consumption.


Download ppt "Mortality benefit from reduction in sodium consumption 1 Hypertension affects one-third of the US population, of which less than half have their blood."

Similar presentations


Ads by Google