1. National Institute of Environmental Health Sciences The NIEHS Training and Career Development Programs The NIEHS Training and Career Development Programs Spanning undergraduate summer research to faculty development; future directions.

2. National Institute of Environmental Health Sciences Training and Career Development Opportunities Short-term Training Undergraduate Students (R25) Diversity Pre-doctoral (F31) Individual MD/PhD (F30) Short-term Training: Medical Students (T35) Institutional Training Grants Pre-, Post-doctoral (T32) Individual Post-doctoral (F32) Clinical Investigator Career Awards (K08, K23) Career Transition Awards (K99/R00) Faculty Development (K02, K24, F33, K25) Independent Research Career

3. National Institute of Environmental Health Sciences “Training” = Ruth L. Kirschstein National Research Service Award (NRSA) Fellowships (F- series) T32 Institutional Training Grants (T32 mechanism) Short-Term Research Training for Health-Professional Students (T35 mechanism)

4. National Institute of Environmental Health Sciences National Research Service Awards Authority and Regulations: Section 487 of Public Health Service Act as amended (42 USC 288) and Federal Regulations 42 CFR 66Authority and Regulations: Section 487 of Public Health Service Act as amended (42 USC 288) and Federal Regulations 42 CFR 66 June 3, 1983 plus amendmentsJune 3, 1983 plus amendments

5. National Institute of Environmental Health Sciences Legislative Framework: Training Grants and Fellowships U. S. Citizen or Permanent ResidentU. S. Citizen or Permanent Resident Research or training to undertake research: predoctoral leading to PhD, postdoctoral researchResearch or training to undertake research: predoctoral leading to PhD, postdoctoral research Training on full time basisTraining on full time basis Max time of support: 5 years predoctoral, 3 years postdoctoralMax time of support: 5 years predoctoral, 3 years postdoctoral Public or Nonprofit Private Institution (T32)Public or Nonprofit Private Institution (T32)

6. National Institute of Environmental Health Sciences NRSA Budget Formula Stipend ($21,600 predoctoral, $38,496- $53,112 postdoctoral)Stipend ($21,600 predoctoral, $38,496- $53,112 postdoctoral) Tuition and fees (60% up to $16,000)Tuition and fees (60% up to $16,000) TravelTravel Training related expenses including Health Insurance ($4,200 per predoctoral, $7850 per postdoctoral)Training related expenses including Health Insurance ($4,200 per predoctoral, $7850 per postdoctoral) No direct research fundingNo direct research funding

7. National Institute of Environmental Health Sciences NIEHS NRSA Programs Individual Fellowships 55 total fellowships 27 - F30 Individual Predoctoral MD/PhD Fellowships 13 - F31 Individual Diversity Predoctoral Fellowships 15 - F32 Individual Postdoctoral Fellowships 0 – F33 Individual Senior Fellowships $2.1 M total cost Average: $38,400 total

8. National Institute of Environmental Health Sciences NIEHS NRSA Programs T35 Short-Term Research Training for Health- Professional Students Research training grants for short-term predoctoral positions reserved specifically to provide full-time, health-related research training experiences during the summer or other "off-quarter" periods. 4 T35s 28 med students total $1.0 M total cost

9. National Institute of Environmental Health Sciences NRSA Programs T32 Institutional Training Grants 48 T32 Programs 271 predoctoral trainees 147 postdoctoral trainees $16.4 M total cost Average program 6 predocs 3 postdocs $350,000 total cost Program size span: 2 predocs + 1 postdoc to 20 predocs + 8 postdocs

10. National Institute of Environmental Health Sciences Kirschstein-NRSA training grants and fellowships Funding in current and constant dollars – NIH total

11. National Institute of Environmental Health Sciences Kirschstein-NRSA training grants and fellowships Pre- and Post-Doctoral full-time training positions awarded

12. National Institute of Environmental Health Sciences TF 12 PRE AND POST-DOCTORAL POSITIONS AS A PERCENT OF ALL KIRSCHSTEIN-NRSA POSITIONS Number of individuals appointed to institutional training positions are estimates Fiscal Year Percent of all Positions

13. National Institute of Environmental Health Sciences TF 13 Number of individuals appointed to institutional training positions are estimates PRE AND POST-DOCTORAL KIRSCHSTEIN-NRSA RESEARCH TRAINING POSITIONS BY PARTICIPATING INSTITUTES AND CENTERS FY 2007 Number of Positions Participating NIH Institutes and Centers

14. National Institute of Environmental Health Sciences NIEHS Mission Statement The mission of the NIEHS is to reduce the burden of human illness and disability, by understanding how the environment influences the development and progression of human disease. The mission of the NIEHS is to reduce the burden of human illness and disability, by understanding how the environment influences the development and progression of human disease.

15. National Institute of Environmental Health Sciences Recent Directions in Training (2006 Announcement) Recent Directions in Training (2006 Announcement) Multidisciplinary and InterdisciplinaryMultidisciplinary and Interdisciplinary Focus on environmental exposures in human health, human biology and human disease processesFocus on environmental exposures in human health, human biology and human disease processes Emphasis on gene x environment interactions and genomicsEmphasis on gene x environment interactions and genomics Defined focus on NIEHS mission areaDefined focus on NIEHS mission area

16. National Institute of Environmental Health Sciences Trainee Research Projects NIEHS relevant exposures: industrial chemicals or byproducts, metals, pesticides, air pollutants, other inhaled toxicants like particulates or fibers, ambient exposuresNIEHS relevant exposures: industrial chemicals or byproducts, metals, pesticides, air pollutants, other inhaled toxicants like particulates or fibers, ambient exposures Belongs to other NIH Institutes: alcohol, drugs of abuse, pharmaceuticals, infectious or parasitic agents, ionizing radiation, chemotherapeutics, etc.Belongs to other NIH Institutes: alcohol, drugs of abuse, pharmaceuticals, infectious or parasitic agents, ionizing radiation, chemotherapeutics, etc.

17. National Institute of Environmental Health Sciences Training Areas Toxicologically related biomedical sciences and Environmental Medicine: 29 programs; 165 pre + 95 post slotsToxicologically related biomedical sciences and Environmental Medicine: 29 programs; 165 pre + 95 post slots Environmental Epidemiology, Biostatistics and Bioinformatics: 12 programs; 72 pre + 32 post slotsEnvironmental Epidemiology, Biostatistics and Bioinformatics: 12 programs; 72 pre + 32 post slots Environmental Pathology: 4 programs; 18 pre + 13 post slotsEnvironmental Pathology: 4 programs; 18 pre + 13 post slots Human Genes and the Environment: 3 programs; 16 pre + 9 post slotsHuman Genes and the Environment: 3 programs; 16 pre + 9 post slots

18. National Institute of Environmental Health Sciences Models for Training in Toxicological Sciences Interdisciplinary Graduate ProgramInterdisciplinary Graduate Program PhD in Toxicology offered by curriculum or Institute independent of Departmental affiliation, often answering to University AdministrationPhD in Toxicology offered by curriculum or Institute independent of Departmental affiliation, often answering to University Administration Faculty, coursework drawn from multiple Departments, specific core curriculumFaculty, coursework drawn from multiple Departments, specific core curriculum

19. National Institute of Environmental Health Sciences Models for Training in Toxicological Sciences Multidisciplinary Graduate ProgramMultidisciplinary Graduate Program Faculty participants from multiple Departments, coordinating administrative structure for training programFaculty participants from multiple Departments, coordinating administrative structure for training program Students receive degrees through DepartmentsStudents receive degrees through Departments Common seminar series, journal clubs, core course(s) in toxicologyCommon seminar series, journal clubs, core course(s) in toxicology

20. National Institute of Environmental Health Sciences Moving Environmental Health Forward: Insights and Opportunities NIEHS Stakeholder Community Workshop in JulyNIEHS Stakeholder Community Workshop in July Stakeholder workshop report: 12 strategic goals identified, then prioritized by voteStakeholder workshop report: 12 strategic goals identified, then prioritized by vote Strategic Plan web site: http://www.niehs.nih.gov/about/od/strate gicplan/index.cfmStrategic Plan web site: http://www.niehs.nih.gov/about/od/strate gicplan/index.cfm http://www.niehs.nih.gov/about/od/strate gicplan/index.cfm http://www.niehs.nih.gov/about/od/strate gicplan/index.cfm

21. National Institute of Environmental Health Sciences Top 6 Topics and Scores Understanding how early life environmental exposures impact development and health across life span (83)Understanding how early life environmental exposures impact development and health across life span (83) Lead the advancement for state-of-the art for characterizing exposure to promote health and prevent disease (71)Lead the advancement for state-of-the art for characterizing exposure to promote health and prevent disease (71) Attract, train, and retain the next generation of environmental health scientists and professionals (65)Attract, train, and retain the next generation of environmental health scientists and professionals (65) Connecting environmental influences to disease through the study of epigenomics and epigenetic mechanism as an opportunity and important long-term goal for NIEHS (62)Connecting environmental influences to disease through the study of epigenomics and epigenetic mechanism as an opportunity and important long-term goal for NIEHS (62) Identify NIEHS as the Prevention Institute within NIH, through research, training, and education that leads to exposure reduction and disease prevention (60)Identify NIEHS as the Prevention Institute within NIH, through research, training, and education that leads to exposure reduction and disease prevention (60) Provide leadership and resources in translating and communicating scientific knowledge on the role of the environment on human health (60)Provide leadership and resources in translating and communicating scientific knowledge on the role of the environment on human health (60)

22. National Institute of Environmental Health Sciences Training and Career Development Opportunities Short-term Training Undergraduate Students (R25) Diversity Pre-doctoral (F31) Individual MD/PhD (F30) Short-term Training: Medical Students (T35) Institutional Training Grants Pre-, Post-doctoral (T32) Individual Post-doctoral (F32) Clinical Investigator Career Awards (K08, K23) Career Transition Awards (K99/R00) Faculty Development (K02, K24, F33, K25) Independent Research Career

23. National Institute of Environmental Health Sciences Training and Career Development Opportunities Undergraduates – Summer researchUndergraduates – Summer research Graduate students – training grants, targeted individual fellowshipsGraduate students – training grants, targeted individual fellowships Postdoctorals – training grants, individual fellowshipsPostdoctorals – training grants, individual fellowships Career Transition – Career Development Awards (K series)Career Transition – Career Development Awards (K series) Faculty DevelopmentFaculty Development