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ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF RADIONUCLIDES

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Presentation on theme: "ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF RADIONUCLIDES"— Presentation transcript:

1 ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF RADIONUCLIDES
Internal Dosimetry Software

2 Introduction

3 Internal dosimetry software
Internal dosimetry related calculations are complicated Biokinetic models Dosimetric models Direct measurement system calibrations Several software packages have been developed to assist the dosimetrist The interpretation of internal dosimetry data can be a complicated process. Since the determination of intake and committed effective dose depends on the use of biokinetic and dosimetric models, interpretation of dosimetry measurements lends itself to the use of computer processing to expedite the interpretation process. Use of such software also contributes to harmonization of evaluation nationally and internationally.

4 Software is available for various tasks
Lookup tables Dose coefficients Retention fractions, etc. Dosimetry calculations Intake Committed equivalent dose Committed effective dose This unit is intended to give a brief overview of software that can be used for to access the data needed for internal dosimetry calculations - dose coefficients and retention fractions, and conduct dosimetry calculations for determination of intake, committed effective dose and committed equivalent dose. The software used for these applications ranges from simple look-up aids to programmes that embodies the biokinetic and dosimetric models developed by the ICRP. Software is also under development that would allow the use of Monte Carlo techniques for computational calibration of direct measurement systems. The unit will not, however, address software that is used for analysis of photon spectra for direct measurement applications.

5 Dose Coefficients and Intake Fractions

6 Rad_toolbox Available, free of charge at This toolbox provides ready access to data of interest in radiation protection of workers and members of the public. Data include interaction coefficients for a, e- , photon and n radiations, nuclear decay data, biological and physiological data, etc. Other supportive data include dose coefficients for intakes of radionuclides, for inhalation, ingestion for members of the public and workers. The ORNL TM report is included in the download.

7 Dose coefficient workers ex ICRP 68
Rad_toolbox Dose coefficient workers ex ICRP 68 The ICRP now has their database on dose coefficients available on CD ROM. The database contains all dose coefficients of Publication 68 (for workers) and Publication 72 for the public. The database includes 10 different AMADs from 1 nm to 10μm and 10 different integration periods from 1 d to the age of 70 y. It includes text of these publications with search function and all the functionality of electronic documents. The database includes biokinetic models for all elements and the results can be saved as an ASCII file for printing. The current price is EUR or $

8 Dose coefficients for workers
Rad_toolbox Contains dose coefficients for single organs (committed equivalent dose) and Committed effective dose . There is the possibility to transfer the values on an Excel file The ICRP now has their database on dose coefficients available on CD ROM. The database contains all dose coefficients of Publication 68 (for workers) and Publication 72 for the public. The database includes 10 different AMADs from 1 nm to 10μm and 10 different integration periods from 1 d to the age of 70 y. It includes text of these publications with search function and all the functionality of electronic documents. The database includes biokinetic models for all elements and the results can be saved as an ASCII file for printing. The current price is EUR or $ Dose coefficients for workers

9 Dose coefficients for members of the population
Rad_toolbox The ICRP now has their database on dose coefficients available on CD ROM. The database contains all dose coefficients of Publication 68 (for workers) and Publication 72 for the public. The database includes 10 different AMADs from 1 nm to 10μm and 10 different integration periods from 1 d to the age of 70 y. It includes text of these publications with search function and all the functionality of electronic documents. The database includes biokinetic models for all elements and the results can be saved as an ASCII file for printing. The current price is EUR or $ Dose coefficients for members of the population

10 ICRP Database of Dose Coefficients
Contains dose coefficients from ICRP Publications 68 (Workers) and 72 (public), including organ doses Inhalation of 10 different AMADs 10 different integration periods Text of ICRP 68 and 72 with search function Biokinetic models for all elements Results can be saved as ASCII files and printed

11 ICRP Database of Dose Coefficients
The ICRP now has their database on dose coefficients available on CD ROM. The database contains all dose coefficients of Publication 68 (for workers) and Publication 72 for the public. The database includes 10 different AMADs from 1 nm to 10μm and 10 different integration periods from 1 d to the age of 70 y. It includes text of these publications with search function and all the functionality of electronic documents. The database includes biokinetic models for all elements and the results can be saved as an ASCII file for printing. The current price is EUR or $

12 ICRP Database of Dose Coefficients

13 ICRP Database of Dose Coefficients
Characteristics of output

14 ICRP Database of Dose Coefficients
On line help tool: Biokinetic model

15 C. Potter: Health Physics retention fraction CD
Pathway : Only Inhalation Retention/ excretion curves in table form CD-ROM attached to HP Nov issue, Vol. 83 n. 5 Intake retention fraction for stable element for respiratory tract, 24h urine, 24h feces, accumulated urine and accumulated feces (useful for 3 day collection of feces) . Absorption Types F, M, S; 5 μm AMAD. No dose coefficients ! The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

16 C. Potter: Health Physics Intake retention fraction

17 C. Potter: Health Physics retention fraction CD HP Vol 83, 5 Nov. 2002
Biokinetic model parameters

18 IAEA SRS 37 Available, free of charge at
www-pub.iaea.org/MTCD/publications/PDF/Pub1190/Pub1190_web.pdf Tables : www-pub.iaea.org/MTCD/publications/PDF/Pub1190/tables.pdf Characteristics Pathway : Inhalation, ingestion, injection. Absorption types , F, M, S, V. AMAD = 1 and 5 μm. Vapors Tables in logarithmic intervals. The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

19 IAEA SRS 37 Standard worker
Sub-set of radionuclides present in ICRP 68 The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

20 IAEA SRS 37 Retention / excretion function (also skeleton organ)
Dose coefficients for both inhalation, ingestion , injection. The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

21 DCAL Available, free of charge at
DCAL is a comprehensive software system for the calculation of tissue dose and subsequent health risk from intakes of radionuclides or exposure to radionuclides present in environmental media. The system includes extensive libraries of biokinetic and dosimetric data and models representing the current state of the art. DCAL maybe used either in an interactive mode or in a batch mode and is intended for experienced users with knowledge of computational dosimetry. The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

22 DCAL The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

23 Rate of equivalent dose in organs
DCAL Rate of equivalent dose in organs The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table. Activity in organs

24 Committed organ doses and committed effective dose
DCAL Committed organ doses and committed effective dose The CD contained in the November, 2002 issue of the Health Physics Journal is designed to provide an electronic representation of contents, including tables of intake fractions developed from models used in determining dose coefficients based on IRCP Report 68 inhalation models. Each element is rendered in PDF format and can be viewed in Adobe Acrobat Reader. If Acrobat Reader is currently installed on your computer, it will launch automatically when you click the document link. The Code Search Engine accessible from the Top Menu Bar can be used to search the various Intake Retention Fractions by Class and Element. A Print hyperlink at the bottom of each table can be used to print a hard copy of the table.

25 Dose Calculation Software

26 Dose calculation software
Software that can be used to estimate intake and internal doses has been developed using various techniques for different applications Table look-up Biokinetic and dosimetric modeling Inhalation Inhalation or ingestion Single intake Multiple intake

27 MONDAL3 Available free of charge, on request at MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

28 MONDAL3 Calculates intake and committed effective doses a point at a time. Several radionuclides Selection between Inhalation and ingestion Selection between workers and members of the population Mode of intake , acute, chronic, uneven chronic. m(t) values up to 1000 days after intake Radioinuclide available 3H, 32P, 51Cr, 54Mn, 59Fe, 57Co, 58,60Co, 65Zn, 86Rb, 85Sr, 89,90Sr, 95Zr, 106Ru, 110mAg, 124Sb, 125Sb, 125,129,131I, 134,137Cs, 140Ba, 141,144Ce, 203Hg, 226,228Ra, 228,232Th, 234,235,238U, 237Np, 238,239,240Pu, 241Am, 242,244Cm and 252Cf. Selection of AMAD = 0.1, 0.3, 1.0, 3.0, 5.0 e 10 µm for workers = 1.0 µm for member of the population MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

29 MONDAL3 Uneven chronic intake
MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

30 Evaluated intake I = M / m(t)
MONDAL3 Type of measurement m(t) value MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance. Evaluated intake I = M / m(t) t = time of measurement M = measurement value E(50) = e(50) * I

31 Integrated Modules for Bioassay Analysis IMBA
Development began in 1997 by the NRPB Features modular structure, interacting via ASCII data sets Implements latest ICRP biokinetic models Fitting uses maximum likelihood method Use data recorded a being less than some minimum detection level Specify multiple intake regimes In 1994 to 1997, ICRP produced an abundance of new biokinetic models which were more realistic and scientifically justifiable than their predecessors. Impending legislation in the UK, which would encourage Approved Internal Dosimetry Services (ADSs) to implement these new models by Jan 2000, combined with a desire to have a unified approach to the interpretation of bioassay measurements prompted the UK ADS's to look for a way forward. The problem was exacerbated by the complex nature of the new models, and also the scarcity of software available to implement the models. It was out this challenge, that the concept of IMBA (Integrated Modules for Bioassay Analysis) originated in 1997. IMBA is now under development by the NRPB and the U.S. D.O.E. The central feature of the IM13A methodology is its modular structure. IMBA consists of six separate modules: each is an independent executable program which performs a specific task. The modules interact with each other via ASCII data sets. They implement the latest ICRP biokinetic models, and the parameter values required by the models are stored outside of the modules, in data sets. By running the modules in a specific order, it is possible to estimate intakes and calculate doses using the new ICRP biokinetic models. Parameter values used by the modules (e.g. AMAD, Absorption Rates etc) can be changed by editing the appropriate data files.

32 IMBA Each module developed independently by two separate organizations Available in four different editions depending on included additional functions Multiple intake regimes Up to 30 associated nuclides Simultaneous bioassay types

33 IMBA Professional Plus
Present status: IMBA Professional Plus MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

34 IMBA Information available at MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

35 IMBA Information MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

36 IMBA Bioassay calculation
MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

37 From Bioassay to intake From Intake to Bioassay
IMBA Use of multiple data-set for unique evaluation via maximum likelihood From Bioassay to intake From Intake to Bioassay MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

38 IMBA Dose Calculations
MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

39 AIDE AIDE (Activity and Internal Dose Estimates) is a software for calculating activities in compartments and committed doses due to occupational exposures, and for performing intake and dose estimates using bioassay data This software has been continuously developed and tested for more than twenty years. Due to its extensive previous uses and challenges AIDE has proved to be suitable to all sorts of users, from beginners in internal dosimetry through its use in courses promoted by IAEA ARCAL (Harmonization of Internal Dosimetry Procedures (ARCAL LXXVIII),) up to advanced users performing evaluations of dose reconstruction. MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

40 Activity and Internal Dose Calculations, Bioassay Interpretation, and
AIDE This software comprises three basic parts, which will be briefly described below: Activity and Internal Dose Calculations, Bioassay Interpretation, and Edit Models. MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

41 AIDE Activity and internal dose calculations
It has the aim to calculate activities in compatments and committed doses due to occupational exposure for performing intake and dose estimates using bioassay data MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

42 AIDE Bioassay interpretation , intake evaluation chi squared test for fitting, possibility to de-select bioassay values. MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

43 AIDE The Model Editing form: Possibility to edit different model from default ICRP models MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

44 AIDE Detail of an original model: Source->Target fractions and biological half lives A demonstration of AIDE will be performed next week. MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

45 IDEA - System Developed as spin-off project of the Research Center Karlsruhe. Expert system. Based on IDEAS Guidelines. MIRDOSE was developed originally in the1980s and subsequently updated. The main purpose of the MIRDOSE software is to perform calculations needed to obtain dose estimates for the various organs of the body and to help the user apply standardized recognized models and techniques for dosimetry into those calculations. The most recent version – MIRDOSE3 - was released in 1994. More than 1400 copies of the software have been distributed since its development, and copies can be found in almost every nuclear medicine department throughout the world. The programs are among the most frequently cited references in nuclear medicine literature. Unfortunately, it is no longer distributed by the Radiation Internal Dose Information Center (RIDIC) at the Oak Ridge Institute for Science and Education because of concerns about potential FDA interpretation of it as a treatment planning device. Although it has not been widely used recently for radiation protection purposes, it is noted here because of its historical significance.

46 Software Information Contacts
RAD_Toolbox ICRP Database of Dose Coefficients C. Potter. Intake retention fraction Health Physics Sellers of Health Physics

47 Software Information Contacts
DCAL MONDAL3 IMBA

48 Software Information Contacts
IAEA SRS 37 Pub1190_web.pdf DCAL MONDAL3

49 Software Information Contacts
IMBA AIDE Rodolfo Cruz-Suarez at IAEA IDEA-System


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