1. Medical Mycology Classification of Mycoses
Hugh B. Fackrell
Filename Fungi_classi.ppt

2. Mycology Mycology: Study of fungi Mycoses: fungal infections
Mytoxicosis- intoxicaton

3. Fungi Fission yeasts Budding Yeasts Molds- filamentous
Penicillium, mushrooms
Yeasts- unicellular
Fission yeasts
Budding Yeasts
Dimorphic Fungi

4. Molds & Fleshy Fungi at tip of hyphae vegetative growth from fragments
Thallus: filaments of cells
visible mycelium
Hypha; individual filament
Septate hyphae
Coenocytic hyphae
Growth:
at tip of hyphae
vegetative growth from fragments

5. Vegetative Structures

6. Mycelium Vegetative Hyphae Reproductive Hyphae
aerial hyphae above media
Reproductive spores

7. Molds: Reproduction Asexual Sexual Grow from fragments asexual spores
Sexual spores ( less frequent)
two strains of fungi
fusion of nuclei

8. Asexual Spores
Conidospore
Arthrospore
Blastospore
Chlamydospore

9. Conidiospore Asexual spore Mitosis Not enclosed by a SAC chains
Conidiophore: filament that forms Conidospore

10. ConidioSpores Arthrospores Blastospores
thickened fragments of septate hyphae
Coccidioides
Blastospores
thickened wall
Bud from the parent cell
Candida, Cryptococcus

11. Chlamydospores
Asexual spore contained within hypha

12. Sporangium Sac of spores Sporangiospore- Spores
Sproangiophore- aerial hypha with sporangium

13. Medically Important Fungi
Deuteromycota- no sexual spores
Zygomycota- coenocytic fungi
Ascomycota-
septate
dust like spore
Basidomycota
fleshy base; mushrooms

14. Opportunistic mycoses
Candidiasis
Aspergillosis,
Mucormycosis
Phycomycosis

15. Superficial Fungal Infections
Skin Infections
limited to Stratum corneum
do not penetrate deeper tissues
No inflammation

16. Superficial mycoses Black piedra White piedra Pityriasis vericolor
tinea nigra

17. Cutaneous Mycoses
Dermatophytoses
Dermatomycoses

18. Subcutaneous Mycoses
Caused by trauma [puncture]and introduction of the fungus and bacteria.
Chromoblasomycosis
Phaeohypomycosis
Mycetoma
Sporotrichosis

19. Systemic or Deep Mycoses
Histoplasmosis
Coccidiomycosis
Blastomycosis
Cryptococcosis

20. Cryptococcosis Cryptococcus neoformans Sporadic Pigeons
Meningitis form
fatal

21. Systemic Mycoses: Disease Patterns
Subacute respiratory infection
Acute infection
Severe disseminated infection

22. Systemic Mycoses: Subacute Respiratory Infection
Low fever
Non-productive cough
Mild & self limiting

23. Systemic Mycoses: Acute Infections
Productive cough
purulent sputum
pain in chest
Weight loss.
night sweats
X-ray positive
one,many lesions
consolidation
Differential diagnosis: pneumonia, tumour.

24. Systemic Mycoses: Severe Disseminated Infections
Acute Infections +
spread to other organs
chronic
Differential diagnosis t.b.

25. Presentation Outline Disease Mechanisms Entry Adaptation Propagation
Dissemination
Host Factors
Fungal Factors
Classification of Mycoses
site
route
virulence
Epidemiology
Fungal Diseases