1. Microarrays for the Masses: Pedagogical Resources for High School through College A. Malcolm Campbell 1,3, Laurie J. Heyer 2,3, Mary Lee S. Ledbetter 4,3, Laura L. M. Hoopes 5,3, Todd T. Eckdahl 6,3, Anne G. Rosenwald 7,3, Edison Fowlks 8,3, Nicholas Dovidio 2, Michael R. Gordon 2, David Moskowitz 2, Mackenzie L. Cowell 1, J. Adam Abele 2, Brian Akin 2, Gavin Taylor 2, Danielle Choi 1, Parul Karnik 2, Peter Lowry 1, Jennifer M. Madden 1, Emily E. Oldham 1,2, B. Daniel Pierce 1, Allison Amore 1, Sheena Bossie 1, Max Citrin 1, Erin Cobain 1, Megan McDonald 1, Marieta Solé 1, Emily Wilson 1, Matt Gemberling 1, Kristen DeCelle 1, Karen Acker 1, Lyana Buckwold 1, Benjamin Whigham 1, Carolyn A. Zanta 9, Kathleen M. Gabric 10, Ben Kittinger 1, Lesli Adler 11, A. Jackie Ryan 1, William T. Hatfield 1,2. 1 Biology Department, 2 Mathematics Department, Davidson College; 3 Genome Consortium for Active Teaching (GCAT), 4 Department of Biology, College of the Holy Cross, Worcester, MA; 5 Department of Biology, Pomona College, Claremont, CA; 6 Department of Biology, Missouri Western State University, Saint Joseph, MO; 7 Department of Biology, Georgetown University, Washington, DC; 8 Department of Biology, Hampton University, Hampton, VA, 9 Howard Hughes Medical Institute Biotechnology Education and Outreach Program, University of Illinois at Urbana-Champaign, Urbana, IL; 10 Hinsdale Central High School, Hinsdale, IL; and 11 Montgomery County Public Schools, Rockville, MD. Wet Lab Simulation & Math Module Open Access Animations & Online Clustering Online Spot SynthesizerResearch Protocols and Chips Thanks to NSF, HHMI, Davidson College, the Waksman Foundation, the James G. Martin Genomics Program, and the Associated Colleges of the South. Do-It-Yourself Teaching Chips MAGIC Tool Software #1741 Top animation is 3 minutes long, bottom one is 30 minutes with interactive questions. Interactive clustering site allows students to explore how clustering works. http://gcat.davidson.edu/Pirelli/index.htm http://gcat.davidson.edu/DGPB/clust/clustering.htm Introductory Curriculum with paper exercise, wet lab simulation is modular and flexible, based on cancer case study. Mathematics module allows students to use math to understand method and basic biology. www.bio.davidson.edu/projects/GCAT/HSChips/HSchips.html Upload spreadsheet, select pattern, and produce tiff files for training and testing student proficiency. www.bio.davidson.edu/projects/GCAT/Spot_synthesizer/Spot_synthesizer.html www.bio.davidson.edu/MAGIC www.bio.davidson.edu/projects/GCAT/DoItYourselfChips/Self_Chips.html www.bio.davidson.edu/GCAT www.bio.davidson.edu/courses/genomics/chip/chip.html Improved display methods, gridding, spot flagging, statistical analysis, and JTreeView connectivity GCAT supports faculty by providing microarrays (HHMI funded) and hands-on, free workshops (NSF funded). Students can design and print their own mini-chips with near 100% success. 2007 workshop participants and one of the their chips. Workshop in 2008 is full and 2009 workshop will accept applications in 2008. macampbell@davidson.edu http://gcat.davidson.edu/masses.html