1. Morbidity & Mortality: 2012 Chart Book on Cardiovascular, Lung, and Blood Diseases National Heart, Lung, and Blood Institute February, 2012

2. Chapter 5 – Blood Diseases 2  The term blood diseases is used here to mean:  Diseases within the diagnostic categories listed in Diseases of Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism of ICD-10  Hemochromatosis * Blood clotting diseases, most of which are subsumed under CVD, have been excluded. As have other blood diseases, such as bleeding and red blood disorders of the newborn and serum hepatitis.

3. 3 Chart 5–1 Deaths From Blood Diseases, Percent By Subgroup, U.S., 2008 Total Deaths = 10,066 (100%) * Compiled from Vital Statistics of the United States, NCHS. Aplastic Anemia 9.5% Other Anemias 35.3% Coagulation Defects 17.9% Sickle Cell Anemia 5.0% Other Diseases of Blood & Blood-Forming Organs 17.5% Hemochromatosis 1.9% Purpura & Other Hemorrhagic Conditions 8.3% Diseases of White Blood Cells 4.5%

4. Chart 5-3 Hospitalizations for Aplastic Anemia by Primary & Secondary Diagnosis, U.S.  4 Hospitalizations (Thousands) Year  Years 1988–2009.

5. Chart 5–4 Death Rates* for Aplastic Anemia By Race & Sex, U.S., 2004–2007 5 Deaths/100,000 Population * Average annual age-adjusted rates.

6. Chart 5-5 Death Rates* for Aplastic Anemia by Age, Race, & Sex, U.S., 2004–2007  6 Deaths/100,000 Population Age (Years) * Average annual rates.  Rates are unreliable for black males aged 35–54 years and black females aged 35–64 years.

7. Chart 5–6 Hospitalization Rates for Sickle Cell Anemia in Blacks by Age, U.S., 1988–2009 7 Hospitalizations/10,000 Population Year

8. Chart 5–7 Death Rates* for Sickle Cell Anemia in Blacks by Sex, U.S., 1980–1984 to 2003–2007 8 Years Deaths/100,000 Population * Age-adjusted average annual rates.

9. Chart 5–8 Death Rates* for Sickle Cell Anemia in Blacks by Age and Sex, U.S., 2004–2007  9 Deaths/100,000 Population Age (Years) * Average annual rates.  Rates are unreliable for black males aged 5–14 and 65–74 years and black females aged 5–14 and 75–84 years.

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