1. Where to Buy How Neutriderm Works Professionals HyperpigmentationHyperpigmentation Pigmentary Disorders Home Customers Voice Buy Now Contact Home >> Pigmentary Disorders >> Hyperpigmentation What is Hyperpigmentation? Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin. Hyperpigmentation may be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. People with darker Asian, Mediterranean, or African skin tones are also more prone to hyperpigmentation, especially if they have excess sun exposure. Many forms of hyperpigmentation are caused by an excess production of melanin. Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. As the body ages, melanocyte distribution becomes less diffuse and its regulation less controlled by the body. UV light stimulates melanocyte activity, and where concentrations of the cells are denser than surrounding areas, hyperpigmentation is affected. Can also be caused by using skin lightening lotions. Another form of hyperpigmentation is Post inflammatory hyperpigmentation. These are dark and discolored spots that appear on your skin following acne that has healed. How to treat hyperpigmentation A wide variety of treatments are available for Hyperpigmentation unfortunately various side effects persist in all current treatments available. Skin peels including salicylic acid peels, application of dry ice to help fade marks, topical applications for home use including those containing combinations of: lactic, kojic, glycolic acid, hydroquinone, retinoid, corticosteroid, nicotinamide Retin-A or alpha-hydroxy acids *Meladerm® is 2014 All Rights Reserved Company InformationCustomer ServiceConnect with Neutriderm About UAS PharmaceuticalsWhere to Buy About Neutriderm Buy Now ProfessionalsTestimonials Contact Us FAQ’s

2. Where to Buy How Neutriderm Works Professionals Periorbital Melanosis (Under eye darkness) Pigmentary Disorders Home Customers Voice Buy Now Contact Home >> Pigmentary Disorders >> Periorbital Melanosis What is Periorbital Melanosis? Periorbital melanosis (also known as Periorbital Hyperpigmentation) is characterized by dark circles around the eyes, which are common, often familial, and frequently found in individuals with dark pigmentation or Mediterranean ancestry. Atopic patients may also exhibit periorbital pigmentation (allergic shiners) due to lower eyelid venous stasis, and treatment is ineffective. How to treat periorbital melanosis A limited number of treatments are available for Periorbital Hyperpigmentation unfortunately various side effects persist in all current treatments available. Various herbal preparations are available with varying results. A skin lightener, which works by slowing down melanin production and removing existing melanin from the skin. *Meladerm® is 2014 All Rights Reserved Company InformationCustomer ServiceConnect with Neutriderm About UAS PharmaceuticalsWhere to Buy About Neutriderm Buy Now ProfessionalsTestimonials Contact Us FAQ’s

3. Where to Buy How Neutriderm Works Professionals Linea Nigra Pigmentary Disorders Home Customers Voice Buy Now Contact Home >> Pigmentary Disorders >> Periorbital Melanosis What is Linea Nigra? Linea nigra (Latin for "black line") is a dark vertical line that appears on the abdomen during about three quarters of all pregnancies. The brownish streak is usually about a centimeter in width. The line runs vertically along the midline of the abdomen from the pubis to the umbilicus, but can also run from the pubis to the top of the abdomen. [2] Linea nigra is due to increased melanocyte- stimulating hormone made by the placenta, which also causes melasma and darkened nipples. Fair-skinned women show this phenomenon less often than women with darker pigmentation. Before it appears, it may be more faintly visible as a white line, called the linea alba ("white line"). [2] How to treat Linea Nigra There is no treatment for linea nigra as it occurs naturally and tends to fade away, in most cases, after delivery. UV rays and sunlight can cause a darkening of the line even through windows so wearing sunscreen may decrease the darkness of the line. After pregnancy, linea nigra may fade but remain visible for some women. During summer months when midlines may come in contact with sunlight, the line may darken the line so it is important to continue wearing sunscreen in order to keep the darkness of the line to a minimum. A skin lightener, which works by slowing down melanin production and removing existing melanin from the skin may be useful *Meladerm® is 2014 All Rights Reserved Company InformationCustomer ServiceConnect with Neutriderm About UAS PharmaceuticalsWhere to Buy About Neutriderm Buy Now ProfessionalsTestimonials Contact Us FAQ’s