1. Prof Desmond Sheridan 1 1

2. 2 2 ESC mission To improve the quality of life of the European population by reducing the impact of cardiovascular disease

3. Prof Desmond Sheridan 3 3 European Cardiac Society Founded in 1950 49 National Societies of cardiology More than 45,000 professional members Founded in 1950 49 National Societies of cardiology More than 45,000 professional members

4. Prof Desmond Sheridan 4 4 ESC Activities Education 1.ESC guidelines for prevention and treatment of CV Disease 2.Seven Scientific Journals 3.ESC Annual Congress - Stockholm Sept 3-7; 25,000 attendees Education 1.ESC guidelines for prevention and treatment of CV Disease 2.Seven Scientific Journals 3.ESC Annual Congress - Stockholm Sept 3-7; 25,000 attendees

5. Prof Desmond Sheridan 5 5 ESC Activities A Heart Plan for Europe 1.Supported the declaration of the Spanish Presidency in 2002 2.Consensus Conference in Partnership with the Irish Presidency 2004 3.Supported the Luxemburg Declaration in 2005 on prevention of CV Disease A Heart Plan for Europe 1.Supported the declaration of the Spanish Presidency in 2002 2.Consensus Conference in Partnership with the Irish Presidency 2004 3.Supported the Luxemburg Declaration in 2005 on prevention of CV Disease

6. Prof Desmond Sheridan 6 6 ESC & CVD Research Creation of a Task Force on the future of CVD Research Conference on the future of CV Research with DG RTD Share the EC’s view on the future of research Creation of a Task Force on the future of CVD Research Conference on the future of CV Research with DG RTD Share the EC’s view on the future of research

7. Prof Desmond Sheridan 7 7 The future of CV Research

8. Prof Desmond Sheridan 8 8 The future of CV Research Investment in cardiovascular research brings results CVD will remain n°1 killer globally - women, underprivileged at high risk Economic cost for the EU (direct & indirect): €300 billion/year Investment in cardiovascular research brings results CVD will remain n°1 killer globally - women, underprivileged at high risk Economic cost for the EU (direct & indirect): €300 billion/year

9. Prof Desmond Sheridan 9 9 The future of CV Research Challenges Clinical Research in EU has declined sharply in recent years EU has lost its dominant position as source of new treatments since 1990 Failing to attract young clinicians to science careers Challenges Clinical Research in EU has declined sharply in recent years EU has lost its dominant position as source of new treatments since 1990 Failing to attract young clinicians to science careers

10. Prof Desmond Sheridan 10 The future of CV Research Research priorities of the next 10 years: 1.Understanding the biological links between atherosclerosis, hypertension, diabetes and obesity 2.Prediction of atherosclerosis plaque behaviour 3.Molecular basis of failing myocardium; Differentiation of CV cells 4.Understanding change in heart rhythm Research priorities of the next 10 years: 1.Understanding the biological links between atherosclerosis, hypertension, diabetes and obesity 2.Prediction of atherosclerosis plaque behaviour 3.Molecular basis of failing myocardium; Differentiation of CV cells 4.Understanding change in heart rhythm

11. Prof Desmond Sheridan 11 The future of CV Research Research priorities of the next 10 years: 5. Individual tailored treatment 6.Gene & stem cell therapy 7.Mechanisms of ageing in the CV system 8.Cardiovascular vulnerability of women Research priorities of the next 10 years: 5. Individual tailored treatment 6.Gene & stem cell therapy 7.Mechanisms of ageing in the CV system 8.Cardiovascular vulnerability of women

12. Prof Desmond Sheridan 12 The future of CV Research Research strategy for Europe: 1.ESC strongly supports FP7 2.ESC supports a doubling of the FP7 budget  Consistent with the Lisbon strategy  to increase R&D spend as % of GDP In Europe  To reverse the decline in Europe’s R&D competitiveness Research strategy for Europe: 1.ESC strongly supports FP7 2.ESC supports a doubling of the FP7 budget  Consistent with the Lisbon strategy  to increase R&D spend as % of GDP In Europe  To reverse the decline in Europe’s R&D competitiveness

13. Prof Desmond Sheridan 13 The future of CV Research Research strategy for Europe: 1.ESC supports the creation of a European research Council to coordinate research in Europe 2.ESC supports the creation of a technology platform for Europe to restore R&D competitiveness Research strategy for Europe: 1.ESC supports the creation of a European research Council to coordinate research in Europe 2.ESC supports the creation of a technology platform for Europe to restore R&D competitiveness

14. Prof Desmond Sheridan 14 The future of CV Research Research needs to be prioritised around the needs of the people of Europe. 1.Health priorities based on causes of death and disability should direct investment. 2.Development of new biotechnologies must be directed to solving the most pressing needs to achieve their full potential. 3.“Blind” technology is not the answer. Research needs to be prioritised around the needs of the people of Europe. 1.Health priorities based on causes of death and disability should direct investment. 2.Development of new biotechnologies must be directed to solving the most pressing needs to achieve their full potential. 3.“Blind” technology is not the answer.

15. Prof Desmond Sheridan 15 The future of CV Research Research strategy for Europe: 1.ESC strongly supports Framework Programme 7 and the need to build a competitive knowledge based Europe. 2.New technologies need to be harnessed around well prioritised health needs in order to optimise their value. Research strategy for Europe: 1.ESC strongly supports Framework Programme 7 and the need to build a competitive knowledge based Europe. 2.New technologies need to be harnessed around well prioritised health needs in order to optimise their value.

16. Prof Desmond Sheridan 16