2. Phosphoribosyl Pyrophosphate (PRPP) Inosine Monophosphate (IMP) Amidophosphoribosyl -transferase (commitment step) 5-phosphoribosylamine Adenylo- succinate Adenine Xanthosine Monophosphate (XMP) Guanine Xanthine Inosine Hypo- xanthine Uric Acid Adenylosuccinate synthase Adenylosuccinate lyase AMP deaminase Nucleotidase Purine Nucleosidase/Phosph orylase IMP dehydrogenase GMP reductase GMP synthase Guanase Xanthine oxido- reductase Xanthine oxoreductase Complex Pathway Pentose Phosphate Pathway

3. AMP deaminase: Missing EC 3.5.4.6, an adenosine monophosphate deaminase. Both JGI and Manatee call an adenosine deaminase with EC 3.5.4.- Guanase: Missing EC 3.5.4.3, a guanine deaminase. RAST calls a hypothetical protein with EC 3.5.4.3 AT THE EXACT SAME BASE PAIRS that JGI and Manatee called an adenosine deaminase. Xanthine oxidoreductase: Missing EC 1.17.3.2 or 1.17.1.4. Xanthine oxoreductase: Same EC numbers as Xanthine Oxidoreductase OVERARCHING QUESTIONS: Is it an adenosine monophosphate deaminase or a guanine deaminase? What is xanthine and why does our organism appear to have no ability to do anything with it (same with other halophiles)?

4. BLAST Result for adenosine / guanine deaminase: Most were cytidine deaminases… But the second highest result was a guanine deaminase! Conclusion: Possibly a guanine deaminase?