1. The University of Chicago Institute for Translational Medicine What Your CTSA Can Do for You! Julian Solway, MD ITM Director

2. NCRR-funded Consortium of 55 CTSAs

3. UHI ACCESS Advocate Illinois Institute of Technology Argonne National Laboratory CTSA Solway/Ross CIHDR CTSA Advisory Boards, esp CARC Comp. Cancer Center COMMITTEE ON CLINICAL AND TRANSLATONAL SCIENCE Meltzer (Beyer/Weichselbaum/McNally/Daum) INSTITUTE FOR TRANSLATIONAL MEDICINE Solway/Ross (Gomez/Pollack) Clinical Trials Cluster Schilsky/Cohn/ Stadler Community Translational Science Cluster Burnet/Miller/Ewigman Population Sciences Cluster Thisted/Ross Core Support & Technology Cluster Weiss Training Cluster Beyer/Meltzer/Olopade NorthShore University HealthSystem CHeSS Center for Medical Ethics IGSBCHAS The University of Chicago ITM/CTSA

4. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

5. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match http://itm.uchicago.edu/intranethttp://itm.uchicago.edu/intranet Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

6. What Your CTSA Can Do for You!

8. Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

9. What Your CTSA Can Do for You! Funding MechanismMaximum Award Amt (Approx # Awards/Yr) Principal Characteristics Application Receipt Dates Clinical and Translational Human Subjects Studies $40,000 (11) Proposed research must involve human subjects - i.e., require IRB approval or IRB exemption 10/15/10 01/15/11 04/15/11 07/15/11 Community Collaborative Research Studies$50,000 (4) Must include investigators from both UC and the Community 10/15/10 01/15/11 04/15/11 07/15/11 Short-term Studies by Post-doctoral Clinician- Scientists $5,000 (5) Restricted to clinician- scientists in training (residents or post-doctoral fellows, or equivalent) Any time Collaborative Studies Among NorthShore University HealthSystem and UC Researchers $75,000 (5) Must include investigators from both UC and NorthShore University HealthSystem 10/15/10 01/15/11 04/15/11 07/15/11 Preclinical Pilot Translational Studies$40,000 (3) Intended for preclinical studies of biology or drug or device development 10/15/10 01/15/11 04/15/11 07/15/11 Core Subsidy Mini-Awards$5,000 (25) Must be used to pay charges of a BSD core Any time Community Projects Mini-Awards$5,000 (6) Must be used to pay costs incurred by a community partner in planning, executing, or reporting a research or demonstration project Any time

10. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

11. What Your CTSA Can Do for You! Clinical Resource Center Inpatient studies – intensive nursing, nutritional support, monitoring of all sorts No hospitalization costs or routine supply costs to investigators (except industry supported research) Outpatient studies – wide range of capabilities, including invasive procedures Extension into community anticipated Satellite CRC at NSUHS, less well subsidized Laboratory services including DNA extraction and storage

12. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

13. What Your CTSA Can Do for You! Biostatistics, study design, ethics, epidemiology advice Biotime Clinic – http://biotime.uchicago.eduhttp://biotime.uchicago.edu Free 1 hr consultation, Tues 9–1, walk-in or appt, in Biostats Lab on MARP 3 Research Ethics Consultation service – Dr. Lainie Ross Adult and pediatric Research Subject Advocates Epidemiology advice on individual basis

14. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

15. What Your CTSA Can Do for You! Bioinformatics support and advice Initiative in Biomedical Informatics (iBi) http://ibi.uchicago.eduhttp://ibi.uchicago.edu Wide range of genetic/genomic computation tools and expertise REDCap research data capture system High performance and grid computing TraM – integrating translational data mart http://tram.uchicago.eduhttp://tram.uchicago.edu and related informatics resources … eVelos – clinical trials management system offered through UCCCC TRIDOM – translational research initiative in the Dept of Medicine http://tridom.bsd.uchicago.edu HIRO – human imaging research office in the Imaging Research Institute

16. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

17. What Your CTSA Can Do for You! Community Engagement help Entrée into community through Community Connections, Center for Community Health and Vitality, interface with Chicago Dept of Public Health, NSUHS connections with Lake County Health Dept Advice on Community-involved research and research priorities from Community Advisory and Review Council (CARC) Practice-based research network (South Side, ACCESS, NSUHS) Emerging relationship with Woodlawn Children’s Promise Community

18. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

19. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

20. What Your CTSA Can Do for You!

21. Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

22. What Your CTSA Can Do for You!

23. Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

24. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

25. What Your CTSA Can Do for You! Support your multidisciplinary research with internal capabilities Research navigation – CTSA Discovery Match Pilot and collaborative seed funding and Core lab subsidies Clinical Resource Center Biostatistics, study design, ethics, epidemiology advice Bioinformatics support and advice; Community Engagement help Plumbing behind the walls – informatics, regulatory, community Support your multidisciplinary research with external capabilities ResearchMatch.org CTSAWeb.org Collaboration Opportunities Resource identification, networking, data sharing projects underway “C3” Chicago CTSA interactions – Community, BERD, CER, Training Enhance Training Opportunities Funding for two T32 graduate students (stipend plus waived tuition) per yr $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) MS in Health Studies aimed at fellows and junior faculty (tuition waived) Committee on Clinical and Translational Science with new courses Genetic Basis of Personalized Medicine, Several Informatics Courses Translational Research Workshops; Pipeline programs (KKC, CSU)

26. What Your CTSA Can Do for You! Questions?