1. Gastrointenstinal system http://www.gistsupport.org/about-gist/what-is-gist.php

2. Endodermal origin – mucosis Splanchnic mesoderm – other layers Development of primitive gut http://www.med.muni.cz/histol/MedAtlas_3/bin-release/MedAtlas.html#app=d8c4&92c7-selectedIndex=3&2b7a-selectedIndex=0 liver pankreas http://www.youtube.com/watch?v=qMnpxP6EeIY&feature=related Adventicie

3. Jícen = Esophagus Cubic + sqamous non- cornified epithelia, longitudinal folds Mucin glands Muscle - upper 2/3 striated muscle and lower 1/3 smooth muscle (try to find) Connective tissue on the surface http://www.acm.uiuc.edu/sigbio/project/digestive/early/esophagus.html PAS (Periodic acid–Schiff) - Stains mucin dark pink

4. Muscle Bazal lamina Cubic epithelia Squamous epithelia Lamina propria (Submucosis) Vessel Magn. x40 Adult

5. Embryonic esophagus E2111/5 8th week iud Magn. x5 Mucosis Adventicia Submucosis Muscle

6. Stomach = Žaludek Cylindric epithelia Plenty mucin and serous glands žlázky Epihtelia Lamina propria Muscle Magn. x5

7. Magn. x40 6th week iud stomach Embryo Mucosis Lamina propria Muscle Adventicia

8. http://education.vetmed.vt.edu

9. Mucosis of villi Muscularis Mucosae Mucosis of crypt Lamina propria Muscle Adult Magn. x5 Cylindric epithelia Enterocytes, undifferentiated cells, goblet cells, paneth´s cells, endocrinne cells Small Intestine = Tenké střevo

10. Magn. x5 11th week of iud Mucosis Adventicia Muscle Submucosis Crypt Villi Embryo Proliferation of mucosis of primitive gut is followed by recanalisation

11. Lieberkuhn´s crypts Lamina propria Vessel Muscularis mucosae Submucosis Magn. x5 Large intestine = Tlusté střevo Adult Cylindric epithelia – short folds goblet cells

12. 10,5th week iud Magn. x5 Embryo Mucosis Lamina Propria Muscle Adventicia