1. KNEE OBJECTIVE STABILITY AND ISOKINETIC THIGH MUSCLE STRENGTH AFTER ANTERIOR CRUCIATE LIGAMENT (ACL) RECONSTRUCTION: A Randomized Six-Month Follow-Up Study M. Sajovic Department of Orthopedics and Sports Trauma Surgery, Celje

2. July 28 - 30, San Francisco 2 OMICS - 3rd Int. Conference & Exhibition on Orthopedics General Teaching Hospital Celje, Slovenia

3. July 28 - 30, San Francisco 3 OMICS - 3rd Int. Conference & Exhibition on Orthopedics Anterior cruciate ligament (ACL) rupture is the most common serious injury of the knee. In the general population, an estimated 1 in 3000 individuals sustains an ACL injury per year in the United States, corresponding to an overall injury rate of approximately 100,000 injuries annually.

4. July 28 - 30, San Francisco 4 OMICS - 3rd Int. Conference & Exhibition on Orthopedics Several risk factors for tearing the ACL have been evaluated in literature. The highest incidence is in individuals 15 to 25 years old who participate in pivoting sports. 70 % of ACL injuries occur in noncontact situations. The risk factors for non-contact ACL injuries fall into four distinct categories: environmental, anatomic, hormonal, and biomechanical.

5. July 28 - 30, San Francisco 5 OMICS - 3rd Int. Conference & Exhibition on Orthopedics The goals of ACL reconstructions are to decrease symptoms, improve function, and return patients to their preinjury level of activity.

6. July 28 - 30, San Francisco 6 OMICS - 3rd Int. Conference & Exhibition on Orthopedics The surgeon has to choose :  graft  fixation

7. July 28 - 30, San Francisco 7 OMICS - 3rd Int. Conference & Exhibition on Orthopedics The most frequently used grafts for intra-articular anterior cruciate ligament (ACL) reconstruction are the autologous patellar tendon (PT) or doubled semitendinosus and gracilis tendons (STG) autografts. There are still controversies about graft selection for primary ACL reconstruction.

8. July 28 - 30, San Francisco 8 OMICS - 3rd Int. Conference & Exhibition on Orthopedics ACL reconstruction Semitendinosus and gracilis tendon autograft (STG) versus Patellar tendon autograft (PT)

9. July 28 - 30, San Francisco 9 OMICS - 3rd Int. Conference & Exhibition on Orthopedics Operative data single technique, different transplant PT transplant Operative data single technique, different transplant PT transplant STG transplant

10. July 28 - 30, San Francisco 10 OMICS - 3rd Int. Conference & Exhibition on Orthopedics RESEARCH ISOKINETIC EVALUATION AND OBJECTIVE STABILITY OF THE KNEE AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION The purpose of this study was to analyze objective stability and isokinetic strength of knee extensor and flexor muscles at 6 months after ACL reconstruction using two different autografts (PT versus STG) with identical fixation (interference screws) in consecutive patients undergoing the same accelerated rehabilitation program. The purpose of this study was to analyze objective stability and isokinetic strength of knee extensor and flexor muscles at 6 months after ACL reconstruction using two different autografts (PT versus STG) with identical fixation (interference screws) in consecutive patients undergoing the same accelerated rehabilitation program.

11. July 28 - 30, San Francisco 11 OMICS - 3rd Int. Conference & Exhibition on Orthopedics From January 2010 to February 2011 57 patients were randomly assigned: Group I ( 29 patients ) Group I ( 29 patients ) STG autograft STG autograft Group II ( 28 patients ) Group II ( 28 patients ) PT autograft PT autograft

12. July 28 - 30, San Francisco 12 OMICS - 3rd Int. Conference & Exhibition on Orthopedics INCLUSION CRITERIA Time from ACL injury to surgery less than 12 months Time from ACL injury to surgery less than 12 months No previous ligamentous injury and surgery of either knee No previous ligamentous injury and surgery of either knee No previous meniscal pathology treated with resection or repair No previous meniscal pathology treated with resection or repair No chondral lesions diagnosed by arthroscopy or MR investigation No chondral lesions diagnosed by arthroscopy or MR investigation

13. July 28 - 30, San Francisco 13 OMICS - 3rd Int. Conference & Exhibition on Orthopedics SURGICAL TECHNIQUE AND REHABILITATION Apart from the graft harvesting the surgical technique was identical Apart from the graft harvesting the surgical technique was identical All procedures were performed by the first author (M.S.) All procedures were performed by the first author (M.S.) Meniscal surgery were performed in 51% of patients in STG group and in 62% of patients in PT group (P =.408). Meniscal surgery were performed in 51% of patients in STG group and in 62% of patients in PT group (P =.408). All the patients were rehabilitated according to the same accelerated protocol with immediate full weight-bearing and full range of motion without use of rehabilitation brace. All the patients were rehabilitated according to the same accelerated protocol with immediate full weight-bearing and full range of motion without use of rehabilitation brace. The rehabilitation program has been completed in the Unitur Spa and Rehabilitation Center Zreče The rehabilitation program has been completed in the Unitur Spa and Rehabilitation Center Zreče

14. July 28 - 30, San Francisco 14 OMICS - 3rd Int. Conference & Exhibition on Orthopedics

15. July 28 - 30, San Francisco 15 OMICS - 3rd Int. Conference & Exhibition on Orthopedics METHODS All postoperative measurements were performed in the Unitur Spa and Rehabilitation Center Zreče by the same senior physical therapist All postoperative measurements were performed in the Unitur Spa and Rehabilitation Center Zreče by the same senior physical therapist Isokinetic strength and endurance of the extensor and flexor muscle groups was measured with the isokinetic dynamometer En – Knee (Enraf – Nonius). Isokinetic strength and endurance of the extensor and flexor muscle groups was measured with the isokinetic dynamometer En – Knee (Enraf – Nonius). Objective AP knee laxity measurements were performed by using the KT-1000 arthrometer (MEDmetric, San Diego, CA) Objective AP knee laxity measurements were performed by using the KT-1000 arthrometer (MEDmetric, San Diego, CA)

16. July 28 - 30, San Francisco 16 OMICS - 3rd Int. Conference & Exhibition on Orthopedics ISOKINETIC TESTING OF THE KNEE Isokinetic measurements of extensor and flexor knee muscles is performed in an open kinetic chain Isokinetic measurements of extensor and flexor knee muscles is performed in an open kinetic chain Testing is always performed on both sides (first healthy then the injured extremity) Testing is always performed on both sides (first healthy then the injured extremity) Measurements are safe and have a high repeatability Measurements are safe and have a high repeatability

17. July 28 - 30, San Francisco 17 OMICS - 3rd Int. Conference & Exhibition on Orthopedics KT-2000 arthrometer (MEDmetric, San Diego, CA)

18. July 28 - 30, San Francisco 18 OMICS - 3rd Int. Conference & Exhibition on Orthopedics METHODS ISOKINETIC AND KNEE LAXITY EVALUATIONS ENDURANCE TEST POWER TEST KT-1000 AP LAXITY 3 months postoperatively 6 months postoperatively angular velocity of 180°/s angular velocity of 60°/s KT- 1000 arthrometer ROM 20°- 90° ROM 10°- 90° 134 N 134 N manual maximum force manual maximum force 25 repetitions 6 repetitions average of three measurements

19. July 28 - 30, San Francisco 19 OMICS - 3rd Int. Conference & Exhibition on Orthopedics ISOKINETIC RESULTS Group STG Group PT P(STG/PT) Average deficit (%) SD Average deficit (%) SD Enduran ce test 180 0 /s Extensor muscles 18.814.614.6 21.5 17.617.617.617.6.527 Flexor muscles 5.213.213.2 3.9 8.68.68.68.6.667.667.667.667 Power test 60 0 /s Extensor muscles 14.014.09.79.7 26.726.726.726.7 10.3.00015.00015 Flexor muscles 3.93.916.816.8 1.4 10.110.110.110.1.497

20. July 28 - 30, San Francisco 20 OMICS - 3rd Int. Conference & Exhibition on Orthopedics KT-1000 measurements at 6 months postoperatively Group STG Group PT P (STG/PT) (STG/PT) Average (mm) SD SD 134 N 1.6 1.5 1.41.41.41.41.6. 509 Manual maximum 1.9 1.6 1.71.71.71.7 1.7. 558. 558

21. July 28 - 30, San Francisco 21 OMICS - 3rd Int. Conference & Exhibition on Orthopedics DISCUSSION Average deficit in flexor muscle strength between the involved and the uninvolved leg was less than 6 % in both groups. This is a very good result, particularly in the STG group, because previous research has found that the hamstring tendons harvest significantly reduces the flexor strength for approximately 1 to 2 years after surgery Average deficit in flexor muscle strength between the involved and the uninvolved leg was less than 6 % in both groups. This is a very good result, particularly in the STG group, because previous research has found that the hamstring tendons harvest significantly reduces the flexor strength for approximately 1 to 2 years after surgery Excellent results resulted from good surgery technique of an experienced surgeon as well as rehabilitation program focusing on due and proper stretching and strengthening of flexor muscles Excellent results resulted from good surgery technique of an experienced surgeon as well as rehabilitation program focusing on due and proper stretching and strengthening of flexor muscles

22. July 28 - 30, San Francisco 22 OMICS - 3rd Int. Conference & Exhibition on Orthopedics CONCLUSION At 6 months after surgery, we found significantly lower isokinetic quadriceps peak torque in the PT group compared with the STG group at angular velocity of 60°/s At 6 months after surgery, we found significantly lower isokinetic quadriceps peak torque in the PT group compared with the STG group at angular velocity of 60°/s We did not find significant difference in flexor muscle power comparing both groups We did not find significant difference in flexor muscle power comparing both groups We did not find significant differences in knee laxity measurements between the two study groups We did not find significant differences in knee laxity measurements between the two study groups No significant correlation was found between the knee objective stability and the isokinetic thigh muscle strength. No significant correlation was found between the knee objective stability and the isokinetic thigh muscle strength.

23. July 28 - 30, San Francisco 23 OMICS - 3rd Int. Conference & Exhibition on Orthopedics THANK YOU FOR YOUR ATTENTION